DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patj and mpz-4

DIOPT Version :9

Sequence 1:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster
Sequence 2:	NP_500654.1	Gene:	mpz-4 / 177255	WormBaseID:	WBGene00019165	Length:	402	Species:	Caenorhabditis elegans

Alignment Length:	419	Identity:	90/419 - (21%)
Similarity:	146/419 - (34%)	Gaps:	112/419 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 QAIELVNDGTGLGFGIIGARNSGVIVKTILPGG--------VADKDGRLRSGDHILQIGDVNLHE 204
            :.|:.|.:..|...|.|.||...|:   ||.|.        :.:....|...|.|.|:|.||.|.
Worm    19 EGIDTVWERPGFKKGEIEARVKDVV---ILRGEPVPNSYKMLVEATFELPKKDKITQLGLVNRHG 80

  Fly   205 MVSEQVAAVLRQSGTHVRLVVARPVEQSVPTPQYALEPGTAVVP---TRVLVDPAELERYL-IST 265
            :|:              |:..|.|.:.       |:.||..::.   |.|..|..:|..:: .:|
Worm    81 LVT--------------RVHYASPFKG-------AILPGDIILQVNGTTVSFDEKQLTEHVDETT 124

  Fly   266 GYPEIFGESSTASTPQTTTEDDRFVYRGETSMLIDPNIDLEELL-ALPETE--------KLQVEL 321
            |...:.....|.....|||.....| |...|:..|..:.:.::| :..||:        |.::..
Worm   125 GGASLQSNVKTVKRKPTTTPKTEPV-RAPHSLYPDFKVVVGKILNSKSETKITVLVARLKNRMST 188

  Fly   322 KKDANGL------GITIAGYVCEKEELSGIFVKSVS---------PGSAADLSGRIRVNDRIIEV 371
            .|..||:      .|.:|.....|....|:.|:.|.         |.|.:..|  :.:.:.||.|
Worm   189 SKIPNGILATQDHTIDLAILYQFKYLQLGLNVQQVDRKVVVNYTIPDSVSHCS--LNIGEAIIAV 251

  Fly   372 DGQSL-----------QGYSNHQAVELLKK-----------SGQVVNL-----RLERYLRGPKFE 409
            |.:.:           :|:..:..:.||.:           .||:.|:     |.:..|.|...:
Worm   252 DDKPINTLADNRQRFREGFEANGWIRLLVEYPNTDPIKNMVRGQLANVMRTAERPQYLLCGDVRK 316

  Fly   410 QLQQAIAA--NDKL------PSSAPGTPSRAPMPTPVATTSSATTT---PSRSITRELEEEALPA 463
            ...:.|.|  |.|.      ....||...:        ..|.|..|   |:.......||..:||
Worm   317 YFVEGIEALKNGKALAPILKEEEGPGEVGK--------KKSDAKVTKKDPAVGFNNTTEEFFIPA 373

  Fly   464 ---PEAFMTTPPSVTTMTTTTLSSFGAGK 489
               .:.|:..||..|.:|.:..|:....|
Worm   374 EWNSKLFVWLPPLKTKVTESASSNMPVKK 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492	19/79 (24%)
		PDZ_signaling	318..400	CDD:238492	23/123 (19%)
		PDZ_signaling	557..643	CDD:238492
		PDZ_signaling	726..807	CDD:238492
mpz-4	NP_500654.1	PDZ	<81..130	CDD:381812	13/69 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900