Protein Alignment Patj and inaD

DIOPT Version :10

• Sequence 1: NP_477342.1
• Gene: Patj / 44100
• FlyBaseID: FBgn0067864
• Length: 871
• Species: Drosophila melanogaster
• Sequence 2: XP_061501956.1
• Gene: inaD / 1269413
• VectorBaseID: AGAMI1_001959
• Length: 780
• Species: Anopheles gambiae
• Alignment Length: 775
• Identity: 165/775 - (21%)
• Similarity: 265/775 - (34%)
• Gaps: 259/775 - (33%)

  Fly   257 ELERYLISTGYPEIFGESS--------------TASTPQTTTEDDRFVYRGETSMLIDPNIDLEE 307
            ||:.|......|...|:|:              ||.||..|               :.|..|.:.
Mosquito    41 ELDHYRTKAKIPSDSGKSNRKLPLCYPVAKPAPTARTPADT---------------VPPPADAKR 90

  Fly   308 -----------LLALPETEKLQ--------VELKKDANGLGITIAGYVCE--KEELSGIFVKSVS 351
                       :.|||.:.||:        |..|.:.:..|.:|.|....  .:..||:|:||:.
Mosquito    91 SPSKERTAEMTVSALPGSVKLEGWGPEKKVVIEKTEKSSFGFSIVGGKVNVGGDVTSGLFIKSII 155

  Fly   352 PGSAADLSGRIRVNDRIIEVDGQSLQGYSNHQAVELLKKSGQVVNL---RLERYLRGPKFEQLQQ 413
            |.|.||..|.:::.|||:.|:..||:..|:.:||..:|.:...:.|   .|||.:|......:.|
Mosquito   156 PESPADKCGELKIGDRILAVNENSLENASHEKAVNYIKTANDRIVLVVQSLERTVREQTNPMVLQ 220

  Fly   414 AIAANDKLPSSAP-------GTPSRAPMPTP------------VATTSSATTTPSRSITRELE-- 457
            ........||..|       |.|.:.|:.||            ..:|.|..::.....:||:|
Mosquito   221 KKVPPPVTPSKTPEVEYIQDGKPKKQPVATPEDNKTLSVPKARQESTDSENSSDDEEDSREMEGK 285

  Fly   458 --------------------EEALPAPEAFMTTPPSV-----------------TTMTTTTLSSF 485
                                ||.....:.:..|...:                 .:..|..||..
Mosquito   286 TFTKAGVEIDRASAGNTKIGEEDAEEEDDYGYTMKKIKKRYAGLGEVDVCTILRDSNETCGLSLC 350

  Fly   486 G--------------------AGKQLVAVRDSLDGSTKII-----------------PT-EVVPL 512
            |                    ||..|....:.|:.:..::                 || :.:.|
Mosquito   351 GHRDRTRMACLIAGINPKGAAAGTSLTVGDEVLEVNGTVLHGRCHLNCSVMIKNLASPTLKFIVL 415

  Fly   513 ADKTEAKNSGVITRHKYYTDPELSDDAETEIIRKWQKIVGSDVEVIVAQIKKFAVGGLGISLEGT 577
            ..||...:..|.....:.||.:.:|:    |:.|::     ||:.|.  :||      |.|..|.
Mosquito   416 RKKTSPDDMAVKPVKHFPTDIDYTDN----IMEKFK-----DVKTIT--VKK------GTSSLGI 463

  Fly   578 VDVEGGREVRPHHYIRSILPDGPVGVNGVLRSGDELLEVNGERLLGMNHLEVVAILKELPLDVRM 642
            :.:||...:.......|.:.:|.......|:.||.||.||.:.|||.|:.....:||:....:.:
Mosquito   464 MIIEGKHSIAGQGIFISDIQEGSTAEKSGLKIGDMLLAVNRDSLLGCNYETAAGLLKKAEGVITL 528

  Fly   643 -VCGRNR--------NSSLLPFSDDTLKKLSNNFENLLPATDRL-------------------VK 679
             :|..|:        |.:.:|.:..:.||..   |....||.|.                   :|
Mosquito   529 KICNPNKEKESDKPANGTAVPGTTPSKKKTE---EMATLATSRAGTPHGTKPEPSPTKEVIDPLK 590

  Fly   680 AKSDGS------LATAGS-----VADG-DSVAAAAASFSKLKSRS-------------------- 712
            |..:.:      :.|.|.     ||.| ||:..:.|:...:..:|
Mosquito   591 APINDNDFTVIDIPTEGKPLGIIVAGGCDSLVKSGAAVMDILPQSVVEKDNRLQIFDQIVEINGF 655

  Fly   713 -----------------LEPLTGLAMWSSQPQIIELVKGD------RGLGFSILDYQDPLDPNDT 754
                             |.|...|.::.:.|...|.|:.|      :.||.:.      ...|..
Mosquito   656 KVNNTCTSEAIKRAVKQLHPKVRLIVYRANPPTTETVEVDLMKKPGKNLGLTF------RAGNPK 714

  Fly   755 LIVIRSLVPGGVAQLDGRLIPGDRLLFVNSINLENASLDQAVQALKGASKGVVRIGVAKP 814
            .|||.||||||.|:.|||:..||.:..:|..:||...::|....||.| :|.|.:.:.:|
Mosquito   715 GIVITSLVPGGSAEFDGRIQLGDIVSHINGDSLEAGGIEQCASLLKTA-QGKVGLRILRP 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Patj	NP_477342.1	L27	12..70	CDD:470651
		PDZ2_MUPP1-like	148..227	CDD:467155
		PDZ3_MUPP1-like	315..401	CDD:467253	29/98 (30%)
		PDZ4_MUPP1-like	556..646	CDD:467156	24/90 (27%)
		PDZ5_MUPP1-like	719..816	CDD:467157	33/102 (32%)
inaD	XP_061501956.1	None