DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rasp and hhatlb

DIOPT Version :9

Sequence 1:	NP_523898.1	Gene:	rasp / 44098	FlyBaseID:	FBgn0024194	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001070858.2	Gene:	hhatlb / 792224	ZFINID:	ZDB-GENE-050506-130	Length:	537	Species:	Danio rerio

Alignment Length:	515	Identity:	110/515 - (21%)
Similarity:	217/515 - (42%)	Gaps:	76/515 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RSLLTRCEIFVYFGVYIAYIVVGLYKIYGLRDHIV---------KEAKFQFPEGWSLYPFSQRRR 62
            ::.|.|.|:::|      .:|:.|..::..: :|.         |..|.....||.   :|.|:.
Zfish     4 KAALPRYELYIY------NVVLCLAMLWAAK-YIFDVSSSNSNRKSFKSSVQPGWY---YSGRKM 58

  Fly    63 DDSNDE----LENFGDFIVSFWPFYLL-HVAVQGFIRWKRPRLQCLGFIGVCALALSVNLDWSSM 122
            |.::.|    ...|.:.|:    |.|. ||..........|:.:.|.|:....||:..::.|:.:
Zfish    59 DTADVEWMMWFSTFREHII----FALSGHVIFGKICSLLAPQYRSLVFMVYGVLAVWSSMGWAYV 119

  Fly   123 VLLVTLIASYYIVSLLSLKFLVWLLSAGW-ILCINVMQKNVWWTDRVGYT------EYVLVIVTM 180
            :|:::.....|.:||:.|::|.:  :||. .|....|:..:.|  :.|:.      ..:|.....
Zfish   120 MLILSHCVLLYSISLVKLRWLCF--TAGLSTLATFKMEPFISW--QAGFVTGGFELRPLLFYGGC 180

  Fly   181 SWSVLRGCSYSLSKIGAKQEDLTRYSLVQYLGYAMYFPCLTYGPIISYQRF--------AARRED 237
            .::::|..|::|.....|..:   ||:::.|.:..|.|...:|||:::.:|        ..|::.
Zfish   181 GFTIMRCMSFALENCEKKDGN---YSILELLKFNFYLPFFYFGPIMTFDKFYVQANNPNLTRKDG 242

  Fly   238 EVQN-------WLGFVGGVLRSAIWWLVMQCALHYFYIHYMSRDVRMVEMMDSVFWQ-HSAGYFM 294
            |:.|       .||.:          :::...||:.||..:..|:::::.:..  |. ....|..
Zfish   243 EMWNISIQALLHLGVI----------IIVAVLLHFMYILSIPSDMKLLKHISD--WALVGLAYLN 295

  Fly   295 GQFFFLYYVVTYGLGIAFAVQDGIPAPNRPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGK 359
            ..:.::...|.:|:....:..|.:..|..|:||..::.:|:  .:||.|:.:||.:.:|..|.||
Zfish   296 LLYDWVKAAVMFGVINTVSKLDHLEPPKPPKCITLLYVFSE--AHFDRGINDFLCKYVYNYLGGK 358

  Fly   360 RSSAAAKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEK-VFKTFTAMPEYQRWTQRHLGA 423
            ..:...:..|:..|:..:.:|.|....|.||:.||...|..|. ..|.||..|...  .:..:..
Zfish   359 HENILDELIASLCTYGIMALWLGPGWVVFIWAFLNCFGLNFELWTVKFFTMEPFIS--IEMAISD 421

  Fly   424 VGAQRLYAMLATQLFIPAAFSNVYFIGGQEIGDFLMRGAYLSGVG-NYVALCFCSYCFFQ 482
            ..::|:.|:..|..|......||..:...|....:.:...|.|.. ..:.:.|.:||..|
Zfish   422 SMSRRIRAVFNTFNFWTIVLYNVLALNSLEFAKLVAKRLLLKGFPFTTITVMFVTYCLIQ 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rasp	NP_523898.1	MBOAT	128..444	CDD:281107	73/339 (22%)
hhatlb	NP_001070858.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1696
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D205353at33208
OrthoFinder	1	1.000	-	-		FOG0002917
OrthoInspector	1	1.000	-	-		otm25345
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1684
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.910