DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rasp and hhatla

DIOPT Version :9

Sequence 1:	NP_523898.1	Gene:	rasp / 44098	FlyBaseID:	FBgn0024194	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_957181.1	Gene:	hhatla / 393861	ZFINID:	ZDB-GENE-040426-1865	Length:	511	Species:	Danio rerio

Alignment Length:	509	Identity:	104/509 - (20%)
Similarity:	209/509 - (41%)	Gaps:	63/509 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RSLLTRCEIFVYFGVY-IAYIVVGLYKIYGLRDHIVKEAKFQFPE----GWSLYPFSQRRRDDSN 66
            ::.|.|.|:::|..|. :|.:....:.|....:::.:.|   |.|    ||..:   .||.|.|:
Zfish     4 KAALPRIELYIYTAVLGLALLWAASWIIEASSENVNRRA---FRENVKPGWHYF---GRRMDVSD 62

  Fly    67 DELENFGDFIVSFWPF--YLL-----HVAVQGFIRWKRPRLQCLGFIGVCALALSVNLDWSSMVL 124
            .|      :::.|..|  ::|     ||..........|:.:.|.::...|||:.:.:.|:.:.|
Zfish    63 FE------WVMWFTTFRNHILFALSGHVIFAKICSMLSPKNRSLIYMMYGALAVLITMGWTYISL 121

  Fly   125 LVTLIASYYIVSLLSLKFLVWLLSAGWILCINVMQKNVWWTDRVGYT------EYVLVIVTMSWS 183
            :::.....|.|:|:..|:|.::.....:....:...:.|   :.|:.      :.:|......:|
Zfish   122 ILSHCIVLYSVALVKKKWLCFVAGLTSLATFKMEPFSGW---QEGFVTGSFDLQDILFYGGCGFS 183

  Fly   184 VLRGCSYSLSKIGAKQEDLTRYSLVQYLGYAMYFPCLTYGPIISYQRF--------AARREDEVQ 240
            ::|..|::|.....|..:   ||.:..:.|..|.|...:||::::.||        ..|:|.|:.
Zfish   184 IMRCMSFALENCEKKDGN---YSFMDLIKYNFYLPFFFFGPVMTFDRFHEQANNPNLTRKEREMW 245

  Fly   241 N----WLGFVGGVLRSAIWWLVMQCALHYFYIHYMSRDVRMVEMMDSVFWQHSAGYFMGQFFFLY 301
            |    .|..:|.:       ||:....|:.||..:..|:::::.:..  |. .||.......:.:
Zfish   246 NITIHALVHLGAI-------LVVDVFFHFLYILTIPGDLKLLKQLSD--WS-LAGLAYSNLVYDW 300

  Fly   302 YVVTYGLGIAFAVQ--DGIPAPNRPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAA 364
            .......|:...|.  |.:..|..|:||..::.:::  .:||.|:.::|.:.:|..:.....|..
Zfish   301 VKAAVMFGVINTVSRLDHLDPPQPPKCITMLYVFAE--THFDRGINDWLCKYVYDYIGENHDSII 363

  Fly   365 AKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEKVFKTFTAMPEYQRWTQRHLGAVGAQRL 429
            .:..||..|||...:|.|....|.|||..|...|..|.......::|.:.......:....::|:
Zfish   364 KELLATICTFAVTTLWLGPCDIVYIWSFFNCFGLNFELWVAKLFSLPPFSTIENNLMSEAMSRRI 428

  Fly   430 YAMLATQLFIPAAFSNVYFIGGQEIGDFLMRGAYLSGVG-NYVALCFCSYCFFQ 482
            ..:.....|......||..:...:....:.:...|.|.. :.:::.|.:||..|
Zfish   429 RGLFNAVNFWQIILYNVLALNSLDFAQLVAKRLLLKGFPLSTLSVLFVTYCGVQ 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rasp	NP_523898.1	MBOAT	128..444	CDD:281107	67/335 (20%)
hhatla	NP_957181.1	MBOAT	127..449	CDD:294479	69/339 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1696
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D205353at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25345
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1684
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.910