DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rasp and SPAC24H6.01c

DIOPT Version :9

Sequence 1:	NP_523898.1	Gene:	rasp / 44098	FlyBaseID:	FBgn0024194	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_592951.3	Gene:	SPAC24H6.01c / 2541508	PomBaseID:	SPAC24H6.01c	Length:	583	Species:	Schizosaccharomyces pombe

Alignment Length:	571	Identity:	121/571 - (21%)
Similarity:	208/571 - (36%)	Gaps:	137/571 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SRLPDRSLLTRCEIFVYFGVYIAYIVVGLYKIYGLRDHIVKEAKF--------QFPEGWSLYPFS 58
            |.:|::|.....|...||.|.::.:.:..:||     |.|...|.        ....||.   |.
pombe    46 SAVPEKSAFGSIEFIFYFSVILSILTIACFKI-----HYVSSPKHPNYKNIEKYLKPGWL---FG 102

  Fly    59 QRRRDDSNDELENFGDFIVSFWPFYLLHVAVQGFIRWKRPRLQCLGFIGVC--ALALSVNLDWSS 121
            | :.|.::.:...|.:.:    |..||.:.|..|: |   ||..|.|....  .||:..|.....
pombe   103 Q-KVDSADFQYSAFRENM----PILLLVIIVYNFL-W---RLVKLVFTKNTNDELAIKNNYRLCF 158

  Fly   122 MVLLVTLIASYYIVSLLSLKFLVWLLSAG-----------WILCINVMQKNVWWTDRVGYTE--- 172
            .:|...|:....::.:|::..:.:|:|..           |.|.|:|    |::.:...|.:
pombe   159 SLLFALLVYGTGVIYVLTIALINYLISKSLKNSIFNPLLTWTLDISV----VFFKEYFAYCKFSS 219

  Fly   173 ------------------YVLVIVTM----------SWSVLRGCSYSLSKIGAKQEDLTR----- 204
                              |||..:||          .||:........:.|..|..:.|.
pombe   220 LHPGLGFLDQYTGILERWYVLFNITMLRLVSFNMDYYWSLKHNSEKLNTLIFDKDREPTTLTFRE 284

  Fly   205 ----------YSLVQYLGYAMYFPCLTYGPIISYQRFAARREDEVQNWLGF--VGGVLRSAIWWL 257
                      |:|..:|.|..|.|....|||||:..|.::.:....:.|.:  :...:|..:..|
pombe   285 RVDYSCLDEDYNLKNFLTYIFYAPLYLAGPIISFNNFMSQMKYPTVSTLKYRNLLYAIRFLVCVL 349

  Fly   258 VMQCALHYFYIHYMSRDVRMVEMMDSVFW-QHSA------GYFMGQFFFLYYVVTYGLGIAFAVQ 315
            .|:..|||.|:..:|:|..         | |:||      .:.:....:|..::.:.|...:::.
pombe   350 TMEFLLHYAYVTAISKDGN---------WNQYSAVESAMISFIVLFMTWLKLLIPWRLFRLWSLI 405

  Fly   316 DGI-PAPNRPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAAAKFGATALTFAFVFV 379
            |.| |..|..||:...:.....|:.:......:|.:.||..|.|...|....|    :.|.||.:
pombe   406 DDIEPPENIVRCMCNNYSAVGFWRAWHRSFNRWLIRYIYVPLGGSNHSILNLF----IIFTFVAL 466

  Fly   380 WHGCYTYVLIWSILNFLCLAAEKV--FKT----FTAMPEYQRWTQRHLGAVGAQ-RLYAMLATQL 437
            ||.....:..|..|..|.:..|::  |.:    .|..|.|     |::...||. .:|.|:...|
pombe   467 WHDISWELFAWGWLIVLFILPERLCCFMSRRTGLTKHPYY-----RYISGFGAALNIYFMIICNL 526

  Fly   438 FIPAAFSNVYFIGGQEIGDFL------MRGAYLSGVGNYVALCFCSYCFFQ 482
            .       .:.:|...|.:.|      ::|| :|.:..::.........||
pombe   527 I-------GFAVGIDGIKNVLVSFFLTLKGA-MSAIAAFIMFFSAVQIMFQ 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rasp	NP_523898.1	MBOAT	128..444	CDD:281107	81/389 (21%)
SPAC24H6.01c	NP_592951.3	MBOAT	<1..229	CDD:294479	42/203 (21%)
SPAC24H6.01c	NP_592951.3	DltB	203..583	CDD:224610	83/397 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	56	1.000	Domainoid score	I3159
eggNOG	1	0.900	-	-		E1_COG1696
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2012
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002917
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102319
Panther	1	1.100	-	-	LDO	PTHR13285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1684
SonicParanoid	1	1.000	-	-		X2607
TreeFam	1	0.960	-	-
	10	9.850