DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and RGD1624210

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:XP_038954996.1 Gene:RGD1624210 / 686977 RGDID:1624210 Length:548 Species:Rattus norvegicus


Alignment Length:517 Identity:106/517 - (20%)
Similarity:176/517 - (34%) Gaps:141/517 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 GAEAMMRCEVANVAGA-----VQWTKDGFALGFSAV-------------IPGF-PRYSVLGDR-K 130
            |.||::.|.|..|...     ::|.:..|:   .||             :||: .|.|::.|: .
  Rat    55 GGEAILPCSVFPVMSVENMEELRWFRTRFS---EAVFVYRDQEEQKEGQLPGYSQRTSLVKDQFH 116

  Fly   131 QGIYNLRISNASINDDADYQCQVGPARLNSAIRANAKLTVISPPASIEIKGYSHNSKVEVRENQD 195
            :|...:||.|...:|...|.|.......:.......|:..:.....:.|||         .|...
  Rat   117 EGKAAVRIQNVQESDSGIYVCHFKQGHFHEEAILELKVA
AMGSVPEVYIKG---------PEEGG 172

  Fly   196 LQLKCIVANAKPAAQIVWYRGNVEYKPEKREDTVEESTAKRFTTTSSLKLKPGPDDDYTEYTCQA 260
            :.:.|:.:...|..|:.|.....|..|...| |:.|.....|:|.:||.|:   |......||..
  Rat   173 VCVVCMTSGWYPEPQVHWRDSRGEDLPASSE-TLHEDAEGLFSTETSLVLR---DSSVRNVTCST 233

  Fly   261 RHKALSPDMPMRATVQLSVLYPPGPPYIEGYSAGETLRRGQ-----TVELMCRSRGGNPPAQLIW 320
            .:..|..:..| |.|.....:|...|:....|  |.|:..|     |..|:.|:.......|..|
  Rat   234 FNPILGQEK
AM-AMVIPEPFFPQASPWKADIS--EILKMMQVLLLLTSCLLMRAHSARLRLQWKW 295

  Fly   321 -----YKNGSQIRM--AYRTSGRLSENI---------------------------YTFTAEAGDN 351
                 .|:.||:..  |.||:..|.|.:                           :|||.:.|. 
  Rat   296 SHFQLEKDESQMTKEDALRTASALREELDRRKAAYNRAWRKAHLYADWRKEHFQTWTFTLDPGS- 359

  Fly   352 KARFRCEASNVMSQNPLKAEVELSVLFAPTHVTVMGPTEARVGDI---VPLTCTTAPSNPPAEIK 413
                 ...:.|:||:.::...:.:::......:|:|......|..   |.|      :|.... |
  Rat   360 -----AHPTLVISQDRMRVTRKDTIVCLDGLFSVLGTKGISSGRYYWEVKL------ANGEGS-K 412

  Fly   414 WMVGGRQVRNATSKT---IVSPEGG-WT---TTSNITAVVEPNKRSL----------VVICHG-- 459
            |::|  ..|....:.   ..|||.| ||   ::....|.|:..:.||          |.:.:.  
  Rat   413 WILG--VCREGVERKGFYFESPEKGFWTVGQSSCGYFAYVDRGRASLSIRQAPQSVGVFVDYDEG 475

  Fly   460 ----LNMQLTENVVSTHTINVLYPPAPPLISGYMEGQIIP---------AGSVQKLLCVSSG 508
                .||....::.|.|..:             :.|.::|         :.:|..:.|||.|
  Rat   476 DISFYNMSDMSHIFSFHKAS-------------LSGTLLPYFRLMSGNVSMTVSSMACVSEG 524

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352 23/103 (22%)
Ig 76..155 CDD:299845 22/88 (25%)
IG_like 186..279 CDD:214653 22/92 (24%)
Ig 197..279 CDD:299845 21/81 (26%)
IG_like 296..376 CDD:214653 22/118 (19%)
Ig 300..361 CDD:299845 18/99 (18%)
Ig 380..454 CDD:299845 20/93 (22%)
IG_like 490..573 CDD:214653 7/28 (25%)
Ig 501..560 CDD:299845 4/8 (50%)
Ig 584..666 CDD:299845
IG_like 585..666 CDD:214653
I-set 678..767 CDD:254352
IGc2 692..757 CDD:197706
Ig 788..849 CDD:143165
Ig 885..960 CDD:143165
FN3 967..1051 CDD:238020
RGD1624210XP_038954996.1 IgV_MOG_like 41..155 CDD:409378 23/102 (23%)
Ig strand B 58..62 CDD:409378 1/3 (33%)
Ig strand C 74..79 CDD:409378 0/4 (0%)
Ig strand E 120..124 CDD:409378 0/3 (0%)
Ig strand F 134..139 CDD:409378 2/4 (50%)
Ig strand G 147..150 CDD:409378 0/2 (0%)
Ig 158..242 CDD:416386 22/96 (23%)
SPRY_PRY_C-I_1 353..506 CDD:293968 33/180 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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