DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sns and Gpa33

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	NP_067623.1	Gene:	Gpa33 / 59290	MGIID:	1891703	Length:	319	Species:	Mus musculus

Alignment Length:	230	Identity:	52/230 - (22%)
Similarity:	88/230 - (38%)	Gaps:	43/230 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   772 TIKSVSENIVVNPGEDAMLSCTV-------EG--------KPLTEEHVKWERV--------GYDM 813
            |:::..:.:....|....|.||.       ||        :..||..|.|..|        .|:.
Mouse    23 TVETTQDILRAARGRSVTLPCTYNTYVSDREGFIQWDKLLRSQTERVVTWNFVTKKYIYGNRYEN 87

  Fly   814 TVKTSTTFANGTSYLHIKDAKREDVGNFRCVADNRVDNPTNRD--ILLIVKFAPEIAKTPTLLRA 876
            .|:.|.......:.:.|.....:|.|.:.|......|...|..  :.|:|...|  :|....::.
Mouse    88 RVRVSNDAELSNASITIDQLTMDDNGTYECSVSLMSDQDVNAKSRVRLLVLVPP--SKPDCSIQG 150

  Fly   877 ASGTGERGRLPCR-AQGSPKPQFIWRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPAD 940
            ....|...:|.|. |:|||.||:.|          ::|..:.::|.:........|::..::...
Mouse   151 EMVIGNNIQLTCHSAEGSPSPQYSW----------KSYNAQNQQRPLTQPVSGEPLLLKNISTET 205

  Fly   941 YGAYECVARNELGEAVETVRLEITSQPDPPLSLNI 975
            .|.|.|.:.|::|  :|:  ..||..|.|| |:||
Mouse   206 AGYYICTSSNDVG--IES--CNITVAPRPP-SMNI 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165	17/83 (20%)
		Ig	885..960	CDD:143165	18/75 (24%)
		FN3	967..1051	CDD:238020	6/9 (67%)
Gpa33	NP_067623.1	V-set	31..138	CDD:284989	21/106 (20%)
		IG_like	31..137	CDD:214653	21/105 (20%)
		IG_like	151..226	CDD:214653	20/88 (23%)
		IGc2	154..218	CDD:197706	17/73 (23%)
		Shisa	<240..>262	CDD:290619
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	267..319
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910