DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and obscnb

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:XP_021326058.1 Gene:obscnb / 572412 ZFINID:ZDB-GENE-070119-5 Length:6781 Species:Danio rerio


Alignment Length:1466 Identity:285/1466 - (19%)
Similarity:485/1466 - (33%) Gaps:417/1466 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 QQHQQQQQQQQQQQHIKWQQHATKRRRCRQHWIKHLQLLRLLAV--------------------- 57
            |.|.:......|   :.|.::..:.|..:::........|:|.:                     
Zfish   755 QMHTEVSNSNVQ---VVWMKNGKELRMGKKYEATSADRKRILTIHNVDQEDVGIYECICDGDKMS 816

  Fly    58 IVLASAPVPSHAQQQKF----RTTPHDLQVLEGAEAMMRCEVANVAGAVQWTKDGFALGFSAVIP 118
            :.||....|:     ||    |..|.:...|.| :.::.||||:...||.|.|:           
Zfish   817 VQLALKEEPA-----KFVNKPRAQPQESDALVG-DVVLSCEVASAGSAVVWKKE----------- 864

  Fly   119 GFPRYSVLGDRK-----QGIY-NLRISNASINDDADYQCQVGPARLNSAIRANAKLTVISPPASI 177
               :..:..|::     ||.. .|.|..|..:|:..|.|:....::...::........|     
Zfish   865 ---QTEITEDKRTTFISQGTQRKLVIRGAKQSDEGHYSCETAEDKMTFLVKIKETRAAFS----- 921

  Fly   178 EIKGYSHNSKVEVRENQDLQLKCIVANAKPAAQIVWYRGNVEYKPEKREDTVE-ESTAKRFTTTS 241
              ...|:..:|:|..:|...|.|.|::||  .::.|::...:..|.|   ||: ||..|    :.
Zfish   922 --NKESYQKEVKVSISQKATLSCEVSDAK--TEVKWFKDGKQLNPSK---TVQMESKGK----SR 975

  Fly   242 SLKLKPGPDDDYTEYTCQARHKALSPDM---PMRATVQLSVLYPPGPPYIEGYSAGETLRRGQTV 303
            .|.|:.....|..||||:..::.|...:   .::||....          :.|.....:...|..
Zfish   976 QLVLENVEKKDAGEYTCEVGNEKLLFKVRVEDLQATFSNK----------DSYQKEVKVATSQKA 1030

  Fly   304 ELMCRSRGGNPPAQLIWYKNGSQIRMAY--------RTSGRLSENIY-----TFTAEAGDNKARF 355
            .|.|..  .:...::.|:|:|.|:..:.        :|...:.||:.     .:|.|||:.|..|
Zfish  1031 TLSCEV--SDIKTEVKWFKDGKQLSSSKTVHMESKGKTRQLIVENVEKKDAGEYTCEAGNEKLVF 1093

  Fly   356 RCEASNVMSQNPLKAEVELSVLFAPTH-VTVMGPTEARVGDIVPLTCTTAPSNPPAEIKWMVGGR 419
            :.:..::.:....|...:..|..|.:. .|:.|    .|.||            ..|:||...|:
Zfish  1094 KIKVEDIQAIFSNKDSYQKEVKVATSQKATLSG----EVSDI------------KTEVKWFKDGK 1142

  Fly   420 QVRNATSKTIVSPEGGWTTTSNITAVVEPNKRSLVV-----------ICHGLNMQL-----TENV 468
            |:  ::.||:.....|.|             |.|:|           ||...|.:|     .|::
Zfish  1143 QL--SSGKTVHMESKGKT-------------RQLIVENVEKKDAGEYICEAGNEKLVFKIRVEDI 1192

  Fly   469 VSTHTINVLYPPAPPLISGYMEGQIIPAGSVQKLLCVSSGGNPLATLT-----------WYKNDK 522
            .:|                     .....|.||.:.|::  :..|||:           |:|:.|
Zfish  1193 QAT---------------------FFDKDSYQKEVKVAT--SQKATLSCEVSDIKTEVKWFKDGK 1234

  Fly   523 RINS--VIRAADKSVSAEITILANVSDNQA-QYRCEASNSA---------TEIPLFQSTTLSVHF 575
            :::|  .:....|..:.:: |:.||....| :|.|||.|..         .:.|:|...:..   
Zfish  1235 QLSSSKTVHMESKGKTRQL-IVENVEKKDAGEYTCEAGNEKLSFKIKVEDIQAPIFNKDSYQ--- 1295

  Fly   576 APETVKIRIEPEELRPGMEATIICDSSSSNPPAKLSWWKDGIPIEGINNTSKPGLWGGTVSTLEF 640
              :.||:...       .:.|:.|:.|......|  |:|||..:    ::||.........|.:.
Zfish  1296 --KEVKVSAT-------QKTTLSCEVSDIKTEVK--WFKDGKQL----SSSKTVHMESKGKTRQL 1345

  Fly   641 RVNVTQEMNGQVYTCQSANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEGESLQVSLQTRAN 705
            .|...::.:...|||::.||.|......|...|:  :..|:...:.........|.:.:|....:
Zfish  1346 VVENVEKKDAGEYTCEAGNEKLAFKIQVAAQPDI--QAAFINKDTYQKEVKVAVSQKATLNCEVS 1408

  Fly   706 PTPVTYKWTKDGTTIPQDG--DHRIFADGGSLNFTRLHRDDAGIYSCSASNSQGGATLNITVVVE 768
            .|....||.|||..:....  |.........|....:.:.|||.|:|...|.:....:.:|.:..
Zfish  1409 DTKTEVKWFKDGKQLSSSKTVDTETKGKTRQLILENVEKKDAGEYTCEVGNEKLTFKVQVTDIQA 1473

  Fly   769 YGTTIKSVSENIVVNPGEDAMLSCTVEGKPLTEEHVKWERVGYDM-TVKTSTTFANG-TSYLHIK 831
            ..|...|..:.:.|...|.|.|||.|..   .:..|||.:.|..: :.||....:.| |..|.:.
Zfish  1474 AFTNKDSYQKEVKVTTSEKANLSCEVSD---LKTEVKWFKDGKQLSSSKTVHMESKGKTRQLILD 1535

  Fly   832 DAKREDVGNFRCVADNR-------VDNP----TNRDILLIVKFAPEIAKTPTLLRAASGTGERGR 885
            :.:::|.|.:.|.|.|.       |..|    ||:|     .:..|:..:         ...:..
Zfish  1536 NVEKKDAGEYTCEAGNEKLVFKILVTEPKAAFTNKD-----SYQKEVKVS---------ASHKAT 1586

  Fly   886 LPCRAQGSPKPQFIWRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARN 950
            |.|.. ...|.:..|.:|.|.|..::|...|.:.:       ...|:|:.....|.|.|.|.|.|
Zfish  1587 LSCEV-SDLKTEVKWFKDGKQLISSKTVHMESKGK-------TRQLVVENAEKKDAGEYTCEAGN 1643

  Fly   951 ELGEAVETVRLEITSQPDPPLSLNILNVTHDTV-------------------TLAWTPGFDGGLK 996
            |  :.|..:::|     |........::|.:||                   ::.|   |..|::
Zfish  1644 E--KLVFKIQVE-----DVATKFQKASMTKETVMFESAEKVILKTEVMSESCSVKW---FKDGVE 1698

  Fly   997 ASYRVRYRMADREQYKYIDGLPNSHKLTIGGLRMNTLYLFSVMSWNELGQSSYLPDLARAETKEA 1061
            .....:|.|....:         |..|.:..........:|..|.::...       .:.:.|||
Zfish  1699 LKDGSKYEMKQEGR---------SRILIVKSSESKDTGTYSCQSADDKVD-------FKVQVKEA 1747

  Fly  1062 P----PPSHPASSLGGGPPTTSQTPLGGTSGMLLVGVGAGIVVVLLNVFVIGCCLH--------K 1114
            |    .|..|.|:                              ||.:...:.|.|:        |
Zfish  1748 PFKFVGPLQPVSA------------------------------VLESTMTLSCSLNKATGNILWK 1782

  Fly  1115 RNEKRLKRGLEL-----------------------MPAELTEDSSNT------PNLVIIGISL-- 1148
            .|.|.:|.|...                       ...|..:|.::|      |.||.....|  
Zfish  1783 HNGKEVKPGGRFSIRTDGTNCILTVSAVAQEDEGEYSCECKDDKTSTKVTIKAPRLVRFTTKLNN 1847

  Fly  1149 --------AAFGFLLVNASL-VAWFFVHQRRKKVAETTNQPAKTATIEMYAPSSYNDTVTGETLS 1204
                    |.|...:....: |.|.     |..|....:...|.|    ...||::.|:|..|..
Zfish  1848 VVANEGKDAIFKCSITPPDVSVRWL-----RNDVPIMASPKFKIA----QGGSSHSLTITAVTQE 1903

  Fly  1205 SVSEKSESYSNEGSSQPEYIDEVRKKAASTYLVEGSDMPPPRYQKDGTLPVIYPNNVVNACTLPH 1269
            ...|.|             :|...|.:.:|..|:  .:|....:|...:.|...|.|.....|..
Zfish  1904 DAGEIS-------------VDAEGKVSKATLQVQ--QLPVTFTKKLADVTVQEQNTVRLEVELSK 1953

  Fly  1270 PR------------HNNGSAAIHMTRDDQMLISKGV 1293
            |.            ...|:..||:....|.|:.|.|
Zfish  1954 PSKDVKWMKNGVVLQQGGNLEIHVDGAKQTLVLKSV 1989

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352 23/106 (22%)
Ig 76..155 CDD:299845 20/84 (24%)
IG_like 186..279 CDD:214653 26/96 (27%)
Ig 197..279 CDD:299845 23/85 (27%)
IG_like 296..376 CDD:214653 17/92 (18%)
Ig 300..361 CDD:299845 16/73 (22%)
Ig 380..454 CDD:299845 15/74 (20%)
IG_like 490..573 CDD:214653 23/105 (22%)
Ig 501..560 CDD:299845 19/72 (26%)
Ig 584..666 CDD:299845 18/81 (22%)
IG_like 585..666 CDD:214653 18/80 (23%)
I-set 678..767 CDD:254352 18/90 (20%)
IGc2 692..757 CDD:197706 16/66 (24%)
Ig 788..849 CDD:143165 19/69 (28%)
Ig 885..960 CDD:143165 19/74 (26%)
FN3 967..1051 CDD:238020 13/102 (13%)
obscnbXP_021326058.1 I-set 10..99 CDD:254352
I-set 110..199 CDD:254352
I-set 282..362 CDD:333254
I-set 369..452 CDD:333254
I-set 459..>523 CDD:333254
FN3 547..634 CDD:238020
Ig 762..809 CDD:319273 5/49 (10%)
IG 836..901 CDD:214652 19/79 (24%)
I-set 928..997 CDD:333254 23/77 (30%)
I-set 1020..1089 CDD:333254 14/70 (20%)
I-set 1112..1181 CDD:333254 21/99 (21%)
I-set 1204..1273 CDD:333254 18/71 (25%)
I-set 1296..1365 CDD:333254 17/81 (21%)
Ig 1401..1469 CDD:319273 15/67 (22%)
I-set 1483..1552 CDD:333254 20/71 (28%)
Ig 1585..1644 CDD:319273 16/66 (24%)
Ig 1689..1732 CDD:319273 8/54 (15%)
I-set 1750..1833 CDD:333254 15/112 (13%)
I-set 1840..1923 CDD:254352 19/104 (18%)
I-set 1930..1999 CDD:333254 13/60 (22%)
I-set 2018..2091 CDD:333254
I-set 2107..2190 CDD:333254
I-set 2196..2279 CDD:333254
I-set 2285..2368 CDD:333254
I-set 2374..2458 CDD:333254
I-set 2464..2547 CDD:333254
I-set 2553..>2620 CDD:333254
I-set 2643..2725 CDD:333254
I-set 2732..2815 CDD:333254
I-set 2820..2905 CDD:333254
I-set 2912..2995 CDD:333254
IG_like 3007..3084 CDD:214653
I-set 3090..3160 CDD:333254
I-set 3178..3260 CDD:333254
I-set 3266..3349 CDD:333254
IG_like 3389..>3452 CDD:214653
I-set 3471..3541 CDD:333254
I-set 3560..3630 CDD:333254
I-set 3649..3719 CDD:333254
I-set 3739..3808 CDD:333254
I-set 3828..3910 CDD:333254
IG 3926..4000 CDD:214652
I-set 4007..4090 CDD:254352
I-set 4095..>4162 CDD:333254
I-set 4186..4269 CDD:254352
I-set 4275..4358 CDD:333254
IG 4370..4449 CDD:214652
IG_like 4461..4538 CDD:214653
I-set 4636..>4700 CDD:333254
FN3 4725..4818 CDD:238020
I-set 4825..4906 CDD:333254
IQ 5065..5087 CDD:197470
I-set 5104..5177 CDD:254352
I-set 5331..5421 CDD:254352
I-set 5469..5559 CDD:254352
I-set 5583..5678 CDD:333254
SH3_Obscurin_like 5807..5869 CDD:212958
RhoGEF 5899..6075 CDD:321997
PH_Obscurin 6084..6208 CDD:270059
I-set 6216..6308 CDD:254352
I-set 6310..6399 CDD:333254
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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