DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sns and cadm1a

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:NP_001107023.2 Gene:cadm1a / 569931 ZFINID:ZDB-GENE-080505-2 Length:446 Species:Danio rerio


Alignment Length:410 Identity:100/410 - (24%)
Similarity:158/410 - (38%) Gaps:119/410 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 LRLLAVIVLASAPVPSHAQQ---QKFRTTPHDLQVLEGAEAMMRCEVANVAGAVQWTKDGFALGF 113
            |..|.:::..||.:.:.|.|   |.......::.|:||..|.:.|.|.|...:|           
Zfish    15 LATLLILITISAAIHTGAAQYPVQSQNLISDNVSVVEGETATISCRVKNNDDSV----------- 68

  Fly   114 SAVIPGFPRYSVLGDRKQGIY--------------------NLRI--SNASINDDADYQCQV--G 154
                     ..:|...:|.||                    .||:  ||.|::|:..|.||:  .
Zfish    69 ---------IQLLNPNRQTIYFKDVRPLKDARFQLVNFSDNELRVSLSNVSLSDEGRYVCQLYTD 124

  Fly   155 PARLNSAIRANAKLTVISPPASIEIKGYSHNSKVEVREN-----QDLQLKCIVANAKPAAQIVWY 214
            |.:     .|.|.:||:.||.         |..:|.||:     .:.::.|....:||||.|.|.
Zfish   125 PPQ-----EAYADITVLIPPG---------NPIIESREDIVSEGNETEITCTSMGSKPAATIRWM 175

  Fly   215 RGNVEYKPEKREDTVEESTAKRFTTTSSLKLKPGPDDDYTEYTCQARHKALSP-------DMPMR 272
            :|:.|.:.:.:   ||.:..|.||.||.|:|....:||.....|...|.|:..       ::..:
Zfish   176 KGDKELQGKSK---VELTYDKMFTVTSWLRLTVTREDDGVPVVCIVDHPAVKDFQAQKYLEVQYK 237

  Fly   273 ATVQLSVLYPPGPPYIEGYSAGETLRRGQTVELMCRSRGGNPPAQLIWYKNGSQI--RMAYRTSG 335
            ..||:.|.:|.||           :|.|:.:||.|.::|...|.|:.|.:....:  ......|.
Zfish   238 PEVQIVVDFPSGP-----------IREGENLELTCLAKGKPEPQQVNWVRVDDDVPSHAVITGSD 291

  Fly   336 RLSENIYTFTAEAGDNKA---RFRCEASNVMSQNPLKAEVELSVLFAPTHVTVMGPTEARVGDIV 397
            ...||:         ||:   .:||.||     |||....:..:||....:|...         :
Zfish   292 LFIENL---------NKSYNGTYRCVAS-----NPLGEAYDDYILFVRDALTTTP---------I 333

  Fly   398 PLTCTT----APSNPPAEIK 413
            |.|.||    |.::||..|:
Zfish   334 PTTTTTTTISATTSPPDVIQ 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352 24/120 (20%)
Ig 76..155 CDD:299845 21/102 (21%)
IG_like 186..279 CDD:214653 28/104 (27%)
Ig 197..279 CDD:299845 25/88 (28%)
IG_like 296..376 CDD:214653 21/84 (25%)
Ig 300..361 CDD:299845 16/65 (25%)
Ig 380..454 CDD:299845 9/38 (24%)
IG_like 490..573 CDD:214653
Ig 501..560 CDD:299845
Ig 584..666 CDD:299845
IG_like 585..666 CDD:214653
I-set 678..767 CDD:254352
IGc2 692..757 CDD:197706
Ig 788..849 CDD:143165
Ig 885..960 CDD:143165
FN3 967..1051 CDD:238020
cadm1aNP_001107023.2 Ig 41..135 CDD:299845 24/118 (20%)
IG_like 46..135 CDD:214653 24/113 (21%)
Ig 156..237 CDD:299845 23/83 (28%)
Ig_3 243..311 CDD:290638 22/92 (24%)
IG_like 247..324 CDD:214653 25/101 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.