DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and tmigd1

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	NP_001091718.1	Gene:	tmigd1 / 559127	ZFINID:	ZDB-GENE-080303-6	Length:	251	Species:	Danio rerio

Alignment Length:	224	Identity:	62/224 - (27%)
Similarity:	98/224 - (43%)	Gaps:	60/224 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 TIICDSSSSNPPA--KLSWWKDG----IPIEGINNTS----KPGLWGGTVSTLEFRVNVTQEMNG 650
            |:.|.:.:::|.:  :|.|:::|    :|.|.:.:.|    :|               ||:|.:|
Zfish    45 TLTCMTDNTDPSSQQELQWFRNGARVKLPEENMMSRSSLCVQP---------------VTKEDDG 94

  Fly   651 QVYTCQSANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGV---EGESLQVSLQTRANPTPVTYK 712
            .|:|||...:|   |.:..|..||.|     ||..:..:.|   |.....:|.:.|||| |||..
Zfish    95 AVFTCQLKGDA---SVNSTVEFDVSY-----PPDLNDTIEVFVQETNDAVLSCEVRANP-PVTVV 150

  Fly   713 WTKDGTTIP-QDGDHRIFADG--GSLNFTRLHRD-DAGIYSC---SASNSQGGATLNITV---VV 767
            |.|||..:. ..|.::...:|  ..|...:|.|| ..|:|.|   ||.....|.|..:||   |:
Zfish   151 WKKDGEVLDLTTGSYKSTNNGITAQLTIPKLKRDVHQGLYVCETKSAMYGVTGRTFQVTVEDRVI 215

  Fly   768 EY--GTTIKSVSENIVVNPGEDAMLSCTV 794
            .:  |.||..|           .:::||:
Zfish   216 GFPLGPTIAGV-----------VVVACTI 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845	19/79 (24%)
		IG_like	585..666	CDD:214653	19/79 (24%)
		I-set	678..767	CDD:254352	31/101 (31%)
		IGc2	692..757	CDD:197706	24/71 (34%)
		Ig	788..849	CDD:143165	2/7 (29%)
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
tmigd1	NP_001091718.1	Ig	43..>100	CDD:299845	16/69 (23%)
		IG_like	129..210	CDD:214653	26/81 (32%)
		Ig	135..193	CDD:143165	20/58 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910