DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and Nectin4

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:XP_017454387.1 Gene:Nectin4 / 498281 RGDID:1559826 Length:509 Species:Rattus norvegicus


Alignment Length:444 Identity:100/444 - (22%)
Similarity:153/444 - (34%) Gaps:111/444 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    83 VLEGAEAMMRC----EVANVAGAVQWTK----DG---FALGFSA----VIPGF---------PRY 123
            |:.|.:|.:.|    :.....|.|.|.:    :|   .||..|.    |.|.:         || 
  Rat    41 VVLGQDAKLPCFYRGDPDEQVGQVAWARVDPNEGTRELALLHSKYGLHVSPAYEDRVEQPPPPR- 104

  Fly   124 SVLGDRKQGIYNLRISNASINDDADYQCQVG--PARLNSAIRANAKLTVISPPASIEIKGYSHNS 186
                |...|...||  ||...|:.:|:|:|.  ||   .:.:|..:|.|:.||..      |.|.
  Rat   105 ----DPLDGSILLR--NAVQADEGEYECRVSTFPA---GSFQARMRLRVL
VPPLP------SLNP 154

  Fly   187 KVEVRENQDLQL--KCIVANAKPAAQIVWYRGNVEYKPEKREDTVEESTAKRFTTTSSLKLKPGP 249
            ...:.|.|.|.|  .| .|...||..:.|   :.|.|..:...:.:.|  :....||...|.|..
  Rat   155 GPPLEEGQGLTLAASC-TAEGSPAPSVTW---DTEVKGTQSSRSFKHS--RSAAVTSEFHLVPSR 213

  Fly   250 DDDYTEYTCQARHKALSPDMPMRATVQLSVLYPPGPPYIEGYSAGETLRRGQTVELMCRSRGGNP 314
            ..:....||...|..|..|..:..|:|::.|.......:|..:.....|.|.|  |.|.|. |.|
  Rat   214 SMNGQPLTCVVSHPGLLQDQRITHTLQV
AFLAEASVRGLEDQNLWHVGREGAT--LKCLSE-GQP 275

  Fly   315 PAQLIWYKNGSQIRMAYRTSGRLSENIYTFTAEAGDNKARFRCEASNVMSQNPLKAEVEL----- 374
            |.:..|.:....:....|..|    :...|.....::...:.|..||.:|....:..||:     
  Rat   276 PPKYNWTRLDGPLPSGVRVKG----DTLGFPPLTTEHSGVYVCHVSNELSSRASQVTVEVLADPE 336

  Fly   375 ----SVLFAPTHVTVMGPTEARVGDIV------------------------PLTCT--------- 402
                .|......|.|:|...|.:..::                        .||.|         
  Rat   337 DPGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLH 401

  Fly   403 ---TAPSNPPAEIKWMVGGR------QVRNATSKTIVSPEGGWTTTSNITAVVE 447
               |.|.:.|.|   .||.|      .:::.:|.:::|.|....:.|.:|.|.|
  Rat   402 SHHTDPRSQPEE---SVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVRE 452

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352 29/112 (26%)
Ig 76..155 CDD:299845 25/97 (26%)
IG_like 186..279 CDD:214653 23/94 (24%)
Ig 197..279 CDD:299845 20/83 (24%)
IG_like 296..376 CDD:214653 19/88 (22%)
Ig 300..361 CDD:299845 13/60 (22%)
Ig 380..454 CDD:299845 21/110 (19%)
IG_like 490..573 CDD:214653
Ig 501..560 CDD:299845
Ig 584..666 CDD:299845
IG_like 585..666 CDD:214653
I-set 678..767 CDD:254352
IGc2 692..757 CDD:197706
Ig 788..849 CDD:143165
Ig 885..960 CDD:143165
FN3 967..1051 CDD:238020
Nectin4XP_017454387.1 IgV_1_Nectin-4_like 37..145 CDD:409471 29/113 (26%)
Ig strand B 47..51 CDD:409471 1/3 (33%)
Ig strand C 63..67 CDD:409471 1/3 (33%)
Ig strand E 109..113 CDD:409471 1/3 (33%)
Ig strand F 123..128 CDD:409471 2/4 (50%)
Ig strand G 137..140 CDD:409471 1/2 (50%)
IgC1_2_Nectin-3-4_like 148..241 CDD:409501 25/104 (24%)
Ig strand B 166..170 CDD:409501 1/3 (33%)
Ig strand C 179..183 CDD:409501 1/6 (17%)
Ig strand E 205..209 CDD:409501 1/3 (33%)
Ig strand F 219..224 CDD:409501 2/4 (50%)
Ig strand G 234..237 CDD:409501 0/2 (0%)
Ig 265..328 CDD:409353 15/69 (22%)
Ig strand B 265..269 CDD:409353 2/5 (40%)
Ig strand C 278..282 CDD:409353 0/3 (0%)
Ig strand E 298..301 CDD:409353 0/2 (0%)
Ig strand F 311..316 CDD:409353 1/4 (25%)
Ig strand G 325..328 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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