DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and clmp

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	NP_001008177.1	Gene:	clmp / 493539	XenbaseID:	XB-GENE-973667	Length:	332	Species:	Xenopus tropicalis

Alignment Length:	209	Identity:	52/209 - (24%)
Similarity:	83/209 - (39%)	Gaps:	49/209 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   617 IPIEGINNTSKPG------LWGGTVSTLEFRVN----VTQEMNGQV--------------YTCQS 657
            :.||.::|.|..|      ..||.|...|....    |::.:.|..              |.|:.
Frog    47 LDIEWLSNISDHGKQVLLSYSGGQVYNAENHKGRYSFVSKYLEGDASLFIRSLQPSDAGQYICKV 111

  Fly   658 ANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEGESLQVSLQTRANPTPVTYKWT----KDGT 718
            .|....:.:.  :::.||.:|..: ..||....:||:::.::.::.|...|:.|:|.    ||..
Frog   112 KNAGQYQWSF--ITVIVLVKPSEL-ACSSEGAQLEGKNVTLNCKSTAGTKPLNYRWVRVNLKDNV 173

  Fly   719 TIPQDGDHRIFADGGSLNFTRLH---RDDAGIYSCSASNSQGGATLNITVVVEYGTTIKSVSENI 780
            ..|.....||    |..|...||   :.|.|.|.|..||..|..|.::.|      |::|||
Frog   174 ERPVQSTARI----GPENQLLLHNLSKTDNGSYRCEVSNEVGKRTCDVDV------TVQSVS--- 225

  Fly   781 VVNPGEDAMLSCTV 794
              |.|..|.::|.|
Frog   226 --NTGILAGVACGV 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845	14/72 (19%)
		IG_like	585..666	CDD:214653	14/72 (19%)
		I-set	678..767	CDD:254352	27/95 (28%)
		IGc2	692..757	CDD:197706	21/71 (30%)
		Ig	788..849	CDD:143165	3/7 (43%)
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
clmp	NP_001008177.1	V-set	29..127	CDD:369466	14/81 (17%)
		Ig_3	136..208	CDD:372822	21/75 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910