DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and tutl

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:NP_001303307.1 Gene:tutl / 46015 FlyBaseID:FBgn0010473 Length:1536 Species:Drosophila melanogaster


Alignment Length:1327 Identity:266/1327 - (20%)
Similarity:471/1327 - (35%) Gaps:344/1327 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   357 CEASNVMSQNPLKAEVELSVLFAPTHVTVMGPTEARVGDIVPLTCTTAPSN-----PPAE----- 411
            |.|  :.:|:..:...|......|..:.....::.| |||...|.||.|::     .||:     
  Fly    13 CRA--LSTQHNTEKSKEQQQQSQPLEIPEQRASKCR-GDIDRTTTTTIPASKTLTASPAKTAAFT 74

  Fly   412 IKWMVGGRQVRNATSKTIVSP--EGGWTTTSNITAVVEPNKRSLVVICHGLNMQ---LTENVVST 471
            :|.....|..|.|...:|..|  .|..:|.:....|::....||:.:. ..|.|   :.|:.|..
  Fly    75 VKTTRRRRSRRRAEGSSICVPIRRGQGSTPTPTIQVLQFVLVSLLALL-AKNAQAHNIPEDAVHI 138

  Fly   472 HTI---------NVLYP---PAPPLISGYMEGQIIPAGSVQKLLCVSSGGNPLATLTWYKN---- 520
            ..|         :|.:|   |.|.::....:              ||..|:.|....||::    
  Fly   139 TAILGEGVIFNCHVEFPNDHPVPYVLQWDKK--------------VSETGSDLPIYIWYESYPEH 189

  Fly   521 -----DKRINSVIRAADKSVSAEITILANVSD-NQAQYRCEASNSATEIPLFQSTT---LSVHFA 576
                 ..|::.|  :.|....:....|.|:.: :|..|.|:......:....::.|   |.||..
  Fly   190 IEEGYKGRVSRV--SQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAP 252

  Fly   577 PETVKIRIEPEEL---RPGMEATIICDSSSSNPPAKLSWWKDGIPIE-----GINNTSKPGLWGG 633
            |   :..:.||::   ..|....:.|.:..: |..::.|:||..|::     ||.|       .|
  Fly   253 P---RFSVTPEDIIYVNLGDSIILNCQADGT-PTPEILWYKDANPVDPSPTVGIFN-------DG 306

  Fly   634 TVSTLEFRVNVTQEMNGQVYTCQSANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEGESLQV 698
            |    |.|::..:..:...|||.:.|...|.| |.|..:........|||.:.|.  :|||.:..
  Fly   307 T----ELRISTIRHEDIGEYTCIARNGEGQVS-HTARVIIAGGAVIMVPPTNQTK--LEGEKVIF 364

  Fly   699 SLQTRANPTPVTYKWTKDGT------------TIPQDGDHRIFADGGSLNFTRLHRDDAGIYSCS 751
            |.:.:|.|..||.:|.::|:            ||.:|         |||....:..||:|.|.|.
  Fly   365 SCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKD---------GSLIINPIKPDDSGQYLCE 420

  Fly   752 ASNSQGG-ATLNITVVVEYGTTIKSVSENIVVNPGEDA-MLSCTVEGKPLTEEHVKW---ERVGY 811
            .:|..|. .:.:..:.|||...: :.:..:...|...| ::.|.::..|.. ::|.|   :|:..
  Fly   421 VTNGIGDPQSASAYLSVEYPAKV-TFTPTVQYLPFRLAGVVQCYIKSSPQL-QYVTWTKDKRLLE 483

  Fly   812 DMTVKTSTTFANGTSYLHIKDAKREDVGNFRCVADNRVDNPTNRDIL-LIVKFAPEIAKTPTLLR 875
            ...:|.....|||:  |.......|..|.:.|...|.........:: ::|:..|.....|..|.
  Fly   484 PYQMKDIVVMANGS--LLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLY 546

  Fly   876 AASGTGERGRLPC---RAQGSPKPQFIW-RQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKV 936
            ... .|:...:.|   .|:|:.:|...| ||:.:.|..::..:.::.         ...:.::.:
  Fly   547 QRK-VGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKIS---------GGNITIENL 601

  Fly   937 APADYGAYECVARNELGEAVETVRLEIT-SQPDPPLSLNILNVTHDTVTLAWTPGFDGG--LKAS 998
            ...|:|.|:||..||:...:...:|.|. :||..|.::. ...|..::||.|.||:.||  .|..
  Fly   602 RREDFGYYQCVVSNEVATLMAVTQLVIEGTQPHAPYNIT-GKATESSITLQWLPGYSGGSEYKQD 665

  Fly   999 YRVRYRMADREQYKYIDGLPN-SHKLTIGGLRMNTLYLFSVMSWNELGQS--SYLPDLARAETKE 1060
            |.:.:|.|....::.|...|: |.::||.||...|.|.|.|:..|.||..  |.:..:...|...
  Fly   666 YTIWFREAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVRTLEDAP 730

  Fly  1061 APPPSHPASSLGGGPPTTSQTPLGGTSGMLLVGVGAGIVVVLLNVFVIGCCLHKRNEKRLKRGLE 1125
            |.|.:..|::   .||.:.                                            .:
  Fly   731 AAPRNVKAAT---QPPDSF--------------------------------------------FQ 748

  Fly  1126 LMPAE----------LTEDSSNT-----PNLVI----------IGISLAAFGFL------LVNAS 1159
            |||.|          ...||..|     |.|.:          :.::..:.|||      |..|.
  Fly   749 LMPDEADLLAYFDIYFHTDSRGTLVYSPPKLRVKGPKPGPPRNVSVTEVSNGFLITWQSPLERAH 813

  Fly  1160 LVAWFFVHQRRKKVAETTN----QPAKTATIEMYAPSSYNDTVTGET--LSSVSEKSESYSNEGS 1218
            :|.::.:..|.....:|.|    :|.:|..:       ..:.|.|.|  ...::...:||.:...
  Fly   814 IVKFYTIKYRTDAQWKTLNRGQIRPEETQYL-------VKNLVGGRTYYFRVLANSEKSYESSDE 871

  Fly  1219 SQPEYIDEVRKKAASTYLVEG------------------SDMPPPRYQKDGTLPVIYPNNVVNAC 1265
            .:......|:.||.:..:|.|                  :.....:.:|:..:......:..|..
  Fly   872 VKFPVPARVKHKAITAGVVGGILFFIVAIILSVCAVKICNKRKRRKQEKEFNMVACRITDARNIA 936

  Fly  1266 TLPHPRHNNGSAAIH-----MTRDDQMLISK--GVYIPSPSPAPPPD------GSYYNMNSD--- 1314
            ...|..||..:.:|.     :.:..|..||.  .:.|.......|||      ..|.:.|.:   
  Fly   937 ANNHHLHNRSTGSISSGQVPLKKYKQTRISSLTAILIAILHWIWPPDRCTNCHSIYSSPNLEDGD 1001

  Fly  1315 ---------------------RYLSYPPMEYPAALDFTAQPMPMAHL------------QPMTVT 1346
                                 |::.  .:|..:.|.::.|.:...::            ..::..
  Fly  1002 EDDGGGGRRRSVSRIQRSLDGRFVL--DVEGVSKLGYSQQTLESGNVDVVDGGLFERRNSNVSQK 1064

  Fly  1347 SLATNGG---------------PTLIGNGSVAAVAGGSGTLRRGILRGVV-------GVPQPDVT 1389
            |.:.:||               ..|:.:.|..::...:.: .||.|:|::       .||....:
  Fly  1065 SSSDDGGFLSRRNFITARASWRRPLVASSSQLSLQSAADS-ARGFLQGLLKIGAKQSAVPPNSQS 1128

  Fly  1390 HHTSTVGGSPMQMLHDLHPVNLSASTLTTSTTLNGS--------LPTATATLPRQPHGILKDPNR 1446
            :....|.|:..|.:  |.|       .|:|..|.|:        :.|.:.:|.:|..  |..|:|
  Fly  1129 YFDEAVSGARYQNV--LRP-------YTSSNNLYGNADRSRPLHINTISGSLSQQQQ--LYTPSR 1182

  Fly  1447 NKQQQQQQQQQQQQQQLQHQQQLLNAS 1473
            ..:......||.|    .|.||||.:|
  Fly  1183 ISRIFSSSPQQLQ----PHHQQLLLSS 1205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653
Ig 197..279 CDD:299845
IG_like 296..376 CDD:214653 4/18 (22%)
Ig 300..361 CDD:299845 2/3 (67%)
Ig 380..454 CDD:299845 21/85 (25%)
IG_like 490..573 CDD:214653 16/95 (17%)
Ig 501..560 CDD:299845 14/68 (21%)
Ig 584..666 CDD:299845 21/89 (24%)
IG_like 585..666 CDD:214653 21/88 (24%)
I-set 678..767 CDD:254352 27/101 (27%)
IGc2 692..757 CDD:197706 22/76 (29%)
Ig 788..849 CDD:143165 15/64 (23%)
Ig 885..960 CDD:143165 15/78 (19%)
FN3 967..1051 CDD:238020 29/88 (33%)
tutlNP_001303307.1 V-set 137..250 CDD:284989 21/128 (16%)
IG_like 137..229 CDD:214653 19/107 (18%)
I-set 253..341 CDD:254352 25/103 (24%)
IGc2 268..331 CDD:197706 18/74 (24%)
I-set 346..437 CDD:254352 27/101 (27%)
Ig 349..437 CDD:299845 27/98 (28%)
Ig 459..530 CDD:299845 14/73 (19%)
IG_like 549..628 CDD:214653 17/88 (19%)
IGc2 551..617 CDD:197706 15/74 (20%)
FN3 633..725 CDD:238020 29/92 (32%)
FN3 786..874 CDD:238020 16/94 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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