DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP012716

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_001230517.1	Gene:	AgaP_AGAP012716 / 4397681	VectorBaseID:	AGAP012716	Length:	166	Species:	Anopheles gambiae

Alignment Length:	153	Identity:	82/153 - (53%)
Similarity:	106/153 - (69%)	Gaps:	3/153 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   619 IEGINNTSKPGLWGGTVSTLEFRVNVTQEMNGQVYTCQSANEALQRSAHEAVSLDVLYRPKFVPP 683
            |.|.||:||.||||||||:||.::|:||:|:|.||||||.||.||||.:.||:|.|||.|:|..|
Mosquito    12 IAGTNNSSKAGLWGGTVSSLELKLNITQDMDGHVYTCQSTNEMLQRSINVAVNLPVLYEPRFQTP 76

  Fly   684 PSSTAVGVEGESLQVSLQTRANPTPVTYKWTKDGTTIP---QDGDHRIFADGGSLNFTRLHRDDA 745
            ..:...||.||.|.|:|....||:.:.|.|||:|.||.   ..|:.||.::|..||.|:|.|.||
Mosquito    77 AETVVHGVAGEPLTVALVATGNPSSIAYTWTKNGQTIASTGSSGEPRIVSEGPILNITKLERTDA 141

  Fly   746 GIYSCSASNSQGGATLNITVVVE 768
            |:|:|.|.||||.|.:|||:.|:
Mosquito   142 GVYTCEAVNSQGSAMINITLQVK 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845	32/46 (70%)
		IG_like	585..666	CDD:214653	32/46 (70%)
		I-set	678..767	CDD:254352	42/91 (46%)
		IGc2	692..757	CDD:197706	31/67 (46%)
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
AgaP_AGAP012716	XP_001230517.1	I-set	71..163	CDD:254352	42/91 (46%)
AgaP_AGAP012716	XP_001230517.1	Ig	86..163	CDD:299845	37/76 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3515
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D141865at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820