DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and fipi

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	427	Identity:	104/427 - (24%)
Similarity:	166/427 - (38%)	Gaps:	85/427 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   667 HEAVSLDVLYRPKFVPPPSSTAVGVEGESLQVSLQTRANPTPVTYKWTKDGTTIPQDGDHRIFAD 731
            ||::||.         |...:.|....|||.|  |.|:....|...|......|.::...||..:
  Fly    22 HESLSLS---------PAEHSVVRYTNESLIV--QCRSPDPKVELHWKSPKGEIIREHKGRIHIE 75

  Fly   732 GGS-----LNFTRLHRDDAGIYSCSASNSQGGA--TLNITVVVEYGTTIKSVSENIVVNPGEDAM 789
            ..|     :.|..:...|.|.:||.|::   |:  :.:..::|....|....:..:.|..||.|.
  Fly    76 QTSTEQLKIVFAHIALADKGNWSCEAAD---GSLHSKSFDLIVYQKITFTENATVMTVKEGEKAT 137

  Fly   790 LSCTVEGKPLTEEHVKWERVGYDMTVKTS-----TTFANGTSYLHIKDAKREDVGNFRCVA---D 846
            :.|.|:|:|  :.:|.|...|..::...:     ...|:|   |.|....:.|.|.:.|.|   :
  Fly   138 ILCEVKGEP--QPNVTWHFNGQPISAGAADDSKFRILADG---LLINKVTQNDTGEYACRAYQVN 197

  Fly   847 NRVDNPTNRDILLIVKFAPEIAKTPTL-LRAA--SGTGERGRLPCRAQGSPKPQFIW-RQDKKDL 907
            :...:...|.:|:.::..|..:|||.: |:.|  :||   ..|.|.|...|...|.| |:..|..
  Fly   198 SIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGT---ATLMCEALAEPPANFTWYRKHNKLH 259

  Fly   908 PINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARNELGEAVETVRLEITSQPDPPLS 972
            ..||.|       .|.|.:|.|:|.:..:..:.:..|.|.|||:||....|.|||...:|..|.:
  Fly   260 SNNRLY-------TIQSDSYWSSLTIHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSPAN 317

  Fly   973 LNILNVTHDTVTLAWTPGFDGGLKA------------SYRVRYRM-------------ADREQYK 1012
            ..:.....:|        ||..|.|            .:|:.|..             |.|:.|.
  Fly   318 FQLRGFNSNT--------FDVVLSAPRGPPDSPMGVNGFRIEYMTEMEFKTDAGKWTNARRKDYA 374

  Fly  1013 YIDGLPNSHKLTIGGLRMNTLYLFSVMSWNELGQSSY 1049
            :.:|.    ...:..|..:|:||....|.|..|.|.:
  Fly   375 FEEGA----TFLLTNLEPDTVYLVRAASRNLAGFSDF 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352	21/95 (22%)
		IGc2	692..757	CDD:197706	18/69 (26%)
		Ig	788..849	CDD:143165	16/68 (24%)
		Ig	885..960	CDD:143165	24/75 (32%)
		FN3	967..1051	CDD:238020	21/108 (19%)
fipi	NP_787975.1	IG_like	33..115	CDD:214653	20/86 (23%)
		I-set	128..202	CDD:254352	19/78 (24%)
		Ig	133..>193	CDD:299845	17/64 (27%)
		IG_like	228..307	CDD:214653	28/88 (32%)
		Ig	235..305	CDD:143165	24/76 (32%)
		FN3	312..415	CDD:238020	21/108 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910