DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP006350

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_557013.3	Gene:	AgaP_AGAP006350 / 3290147	VectorBaseID:	AGAP006350	Length:	319	Species:	Anopheles gambiae

Alignment Length:	183	Identity:	44/183 - (24%)
Similarity:	68/183 - (37%)	Gaps:	48/183 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   734 SLNFTRLHRDDAGIYSCSASNSQGGATLNITVVVEYG--TTIKSVSENIVV--NPGEDAMLSCTV 794
            :|...|..|.|..||.|..|.....:.....:|::|.  ||...:.|..:|  ..|::..|:|.|
Mosquito   107 TLKLRRTRRKDTDIYECQISTMPVKSLQLYLIVLDYHFLTTTTQILEGTIVYGYKGQNVNLTCIV 171

  Fly   795 ----EGKPLTEEHVKW----ERVGYDMTVKTSTTFANG-TSYLHIKDAKREDVGNFRCVADNRVD 850
                :.:|   .|:.|    :.|.|:...|...:..|. |||..|:.|:.:|.||:.|
Mosquito   172 NHNYDRRP---SHIVWYHQKDIVAYESLRKRGRSSLNSITSYHLIRSAEFDDAGNYTC------- 226

  Fly   851 NPTNRDILLIVKFAPEI-AKTPTLLRAASGTGERGRLPCRAQGSPKPQFIWRQ 902
                         |||: ....|::....|..:.||           ...|||
Mosquito   227 -------------APELYPSASTIVHILDGRWDGGR-----------DVRWRQ 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352	8/32 (25%)
		IGc2	692..757	CDD:197706	8/22 (36%)
		Ig	788..849	CDD:143165	19/69 (28%)
		Ig	885..960	CDD:143165	4/18 (22%)
		FN3	967..1051	CDD:238020
AgaP_AGAP006350	XP_557013.3	Ig	45..139	CDD:299845	8/31 (26%)
		IG_like	46..126	CDD:214653	7/18 (39%)
		IG_like	157..227	CDD:214653	21/92 (23%)
		Ig	165..>226	CDD:143165	18/63 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910