DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and f11r.1

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	NP_001004667.1	Gene:	f11r.1 / 323696	ZFINID:	ZDB-GENE-030131-2416	Length:	292	Species:	Danio rerio

Alignment Length:	255	Identity:	58/255 - (22%)
Similarity:	94/255 - (36%)	Gaps:	51/255 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   692 EGESLQVSLQTRANPTP-VTYKWTKD----GTTIPQDG------DHRIFADGGSLNFTRLHRDDA 745
            ||..||.|..:....|| |.:|: ||    .|.:..||      ..|:......|.|.::.|.|.
Zfish    33 EGVDLQCSYTSDFGATPRVEWKF-KDLKGSQTLVYFDGKPTGQYTGRVTMYDKGLRFNKVTRADT 96

  Fly   746 GIYSC--SASNSQGGATLNITVVVEYGTTIKSVSENIVVNPGEDAMLSC-------------TVE 795
            |.|.|  |.|...|..|:.:||:|.....:..:..::..:  .:..|:|             ..:
Zfish    97 GDYDCEVSGSGGYGENTIKLTVLVPPAKPVSRIPSSVTTS--SNVRLTCFDPVGSPPSTYKWYKD 159

  Fly   796 GKPLTEEHVK---WERVGYDMTVKTSTTFANGTSYLHIKDAKREDVGNFRCVADNRVDNPTNRDI 857
            ..||.|:..|   ::.:.|.|.|      .||.  |......:.|.|::.|.|.|....|...|.
Zfish   160 NTPLPEDPTKFPAFKNLTYKMNV------FNGN--LEFPSVSKMDTGSYFCEASNGEGVPQRGDE 216

  Fly   858 L-----------LIVKFAPEIAKTPTLLRAASGTGERGRLPCRAQGSPKPQFIWRQDKKD 906
            :           ::......:.....||.......::|.||..::...|||.::.|.:.|
Zfish   217 VKMEVRDLNVGGIVAGVIVALLAVGLLLFGLWYASKKGYLPKLSETKQKPQAVYTQPQTD 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352	28/87 (32%)
		IGc2	692..757	CDD:197706	24/77 (31%)
		Ig	788..849	CDD:143165	17/76 (22%)
		Ig	885..960	CDD:143165	7/22 (32%)
		FN3	967..1051	CDD:238020
f11r.1	NP_001004667.1	Ig	22..119	CDD:299845	27/86 (31%)
		IG_like	25..118	CDD:214653	26/85 (31%)
		IG_like	130..210	CDD:214653	17/89 (19%)
		Ig	139..210	CDD:143165	17/78 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910