DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and HLA-DPB1

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:NP_002112.3 Gene:HLA-DPB1 / 3115 HGNCID:4940 Length:258 Species:Homo sapiens


Alignment Length:212 Identity:43/212 - (20%)
Similarity:78/212 - (36%) Gaps:70/212 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   179 IKGYSHNSKVEVRENQDL-QLKCIVANAKPAAQIVWYRGNVEYKPEKREDTVEESTAKRFTTTSS 242
            ::.|.:|.:...|.:.|: :.:.:....:|||: .|         ..::|.:||..|.       
Human    54 LERYIYNREEFARFDSDVGEFRAVTELGRPAAE-YW---------NSQKDILEEKRAV------- 101

  Fly   243 LKLKPGPDDDYTEYTCQARHK-ALSPDMPMRATVQLSVLYPP---GPPYIEGYSAGETLRRGQTV 303
                  ||.       ..||. .|...|.::..||..|...|   ||  ::.::.          
Human   102 ------PDR-------MCRHNYELGGPMTLQRRVQPRVNVSPSKKGP--LQHHNL---------- 141

  Fly   304 ELMCRSRGGNPPA-QLIWYKNGSQIRMAYRTSGRLSENI-----YTF--------TAEAGDNKAR 354
             |:|......|.: |:.|:.||.:     .|:|.:|.|:     :||        |.:.||   .
Human   142 -LVCHVTDFYPGSIQVRWFLNGQE-----ETAGVVSTNLIRNGDWTFQILVMLEMTPQQGD---V 197

  Fly   355 FRCEASNVMSQNPLKAE 371
            :.|:..:....:|:..|
Human   198 YTCQVEHTSLDSPVTVE 214

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653 18/94 (19%)
Ig 197..279 CDD:299845 16/82 (20%)
IG_like 296..376 CDD:214653 19/90 (21%)
Ig 300..361 CDD:299845 17/74 (23%)
Ig 380..454 CDD:299845
IG_like 490..573 CDD:214653
Ig 501..560 CDD:299845
Ig 584..666 CDD:299845
IG_like 585..666 CDD:214653
I-set 678..767 CDD:254352
IGc2 692..757 CDD:197706
Ig 788..849 CDD:143165
Ig 885..960 CDD:143165
FN3 967..1051 CDD:238020
HLA-DPB1NP_002112.3 Beta-1 30..121 18/96 (19%)
MHC_II_beta 42..114 CDD:395773 17/89 (19%)
IgC1_MHC_II_beta_HLA-DP 121..216 CDD:409594 25/115 (22%)
Beta-2 122..215 25/114 (22%)
Ig strand B 140..144 CDD:409594 1/14 (7%)
Ig strand C 155..159 CDD:409594 1/3 (33%)
Ig strand E 186..190 CDD:409594 0/3 (0%)
Ig strand F 197..202 CDD:409594 1/4 (25%)
Ig strand G 212..215 CDD:409594 1/3 (33%)
Connecting peptide 216..225
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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