DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and Igsf9

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:NP_001100667.1 Gene:Igsf9 / 304982 RGDID:1304566 Length:1179 Species:Rattus norvegicus


Alignment Length:1274 Identity:261/1274 - (20%)
Similarity:416/1274 - (32%) Gaps:424/1274 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   380 PTHVTVMGPTEARVGDIVPLTCTTAP--SNPPAE-IKWM-----------------------VGG 418
            |..|:|:|    |.|:...|.|...|  ..||.. |:|:                       ||.
  Rat    24 PEVVSVVG----RAGESAVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGR 84

  Fly   419 RQVRNATSKTIVSPEG------GWTTTSNITAVVEPNKRSLVVICHGLNMQLTENVVSTHTINVL 477
            .:::...|..|   ||      ||...           |.|.:..|..............|:|  
  Rat    85 VRLQTGASLQI---EGLRVEDQGWYEC-----------RVLFLDQHSPEQDFANGSWVHLTVN-- 133

  Fly   478 YPP----APPLISGYMEGQIIPAGSVQKLLCVSSGGNPLATLTWYKNDKRINS------------ 526
            .||    .|||:....|.:.:      .|.||:. |:|...:||....:.:..            
  Rat   134 SPPQFQETPPLVLEVKELEAV------TLRCVAL-GSPQPYVTWKFRGQDLGKGQGQVQVRNGTL 191

  Fly   527 VIRAADKSVSAEITILANVSDNQAQYRCEASNSATEIPLFQSTTLSVHFAPETVKIRIEPEELRP 591
            .||..::..:.:             |.|:|  |:||..:..:|.|.| ..|..:.:......:..
  Rat   192 WIRRVERGSAGD-------------YTCQA--SSTEGSVTHTTQLLV-LGPPVIVVPPNNNTVNA 240

  Fly   592 GMEATIICDSSSSNPPAKL--SWWKDGIPIEGINNTSKPGLWGGTVSTLEFRVNV---------- 644
            ..:.::.|.:.:.  ||.|  ||::|.|.:..|             |.|:.||.:          
  Rat   241 SQDVSLACRAEAY--PANLTYSWFQDRINVFHI-------------SRLQSRVRILVDGSLWLQA 290

  Fly   645 TQEMNGQVYTCQSANEALQRSAHEAVSLDVLY--RPKFVPPPSSTAVGVEGESLQVSLQTRANPT 707
            ||..:...|||..:| ........:..|.|||  :...:||.:...:|:.|   .:....||||.
  Rat   291 TQPDDAGHYTCVPSN-GFPHPPSASAYLTVLYPAQVTVMPPETPLPIGMRG---VIRCPVRANPP 351

  Fly   708 PVTYKWTKDGTTIPQD-------GDHRIFADGGSLNFTRLHRDDAGIYSCSASNSQGGATLNITV 765
            .:...|||||..:..|       |..      |||.....:.|..|.|||:..||.|        
  Rat   352 LLFVTWTKDGQALQLDKFPGWSLGPE------GSLVIALGNEDALGEYSCTPYNSLG-------- 402

  Fly   766 VVEYGTTIKSVSENIVVNPGEDAMLSCTVEGKPLTEEHVKWERVGYDMTVKTSTTFANGTSYLHI 830
                                       |....|:|.           :.:|....|.:     ..
  Rat   403 ---------------------------TAGSSPVTR-----------VLLKAPPAFID-----QP 424

  Fly   831 KDAKREDVGNFRCVADNRVDNPTNRDILLIVKFAPEIAKTPTLLRAASGTGERGRLPCRAQGSPK 895
            |:...::||               ||:|                           :||.|:|.|.
  Rat   425 KEEYFQEVG---------------RDLL---------------------------IPCSARGDPP 447

  Fly   896 PQFIWRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARNELGE-AVETV 959
            |...|.:..:.|.         .:.::||   .::||:..:....:|.:||.|||.:.. .:.|.
  Rat   448 PIVSWAKVGRGLQ---------GQAQVDS---NNSLILRPLTKEAHGRWECSARNAVAHVTISTN 500

  Fly   960 RLEITSQPDPPLSLNILNVTHDTVTLAWTPGFDGGLKASYRVRY----RMADREQYKYID-GLP- 1018
            ...:.:.|....:::::.:... ..::|.||||||....:.|.|    :..||..:.::. .:| 
  Rat   501 VYVLGTSPHVVTNVSVVPLPKG-ANVSWEPGFDGGYLQRFSVWYTPLAKRPDRAHHDWVSLAVPM 564

  Fly  1019 NSHKLTIGGLRMNTLYLFSVMSWNELGQSSY-------------LPDLARAETKEAPPPSHPASS 1070
            .:..|.:.||:..|.|.|||::.|:||...:             .|.:.|....|.|||..|...
  Rat   565 GATHLLVPGLQAYTQYQFSVLAQNKLGSGPFSEIVLSIPEGLPTTPAVPRLPPTEMPPPLSPPRG 629

  Fly  1071 LGGGPPTTSQTPLG------------------------GTSGMLLVGVG-AGIVVVLLNVFVIGC 1110
            |     ...:||.|                        |:.|..::..| ||..:.||...:|..
  Rat   630 L-----VAVRTPRGVLLHWDPPELIPERLDGYILEGRQGSQGWEILDQGVAGTEIQLLVPGLIKD 689

  Fly  1111 CLHKRNEKRL------------------KRGLELMPAELTEDSSNTPNLVIIGISLAAFGFL--L 1155
            .|:   |.||                  ..|||:.|:. |:.....|..|:.|: :....||  .
  Rat   690 VLY---EFRLVAFADSYVSDPSNIANISTSGLEVYPSR-TQLPGLLPQPVLAGV-VGGVCFLGVA 749

  Fly  1156 VNASLVAWFFVHQRRKKVAETTNQPAKTATIEMYAPSSYNDTVTGETLSSVSEKSESYSNEGSSQ 1220
            |..|::|...:::||  .|....:..:.....:::|..               :|..:|..||..
  Rat   750 VLVSILAACLMNRRR--AARRHRKRLRQDPPLIFSPRG---------------RSGPHSAPGSDS 797

  Fly  1221 PEYIDEVRKKAASTYLVEGSDMP-------------PPRYQKDGTL------------------- 1253
            |   |.|.|     :.::||.:|             ||....|..|                   
  Rat   798 P---DSVTK-----FKLQGSPVPSLRQSLLWGEPARPPSPHPDSPLGRGPLPLEPICRGPDGRFV 854

  Fly  1254 --PVIYPNNVVNACTLPHPRHNNGSAAIHMTRDDQMLISKGV-----------------YIPSPS 1299
              |.:.|...........||  ..:..:..:.|.......||                 .:|||.
  Rat   855 MGPTVAPPQEKLCLERSEPR--TSAKRLAQSLDCSSSSPSGVPQPLCITDISPVGQPPAAMPSPL 917

  Fly  1300 PAPPPDGSYYN------MNSDRYLSYPPMEYPAAL---DFT-AQPMPMAHLQP---MTVTSLATN 1351
            |.|.|...|.:      ||.|.  .:||:|.|...   ||. :.|.|.:...|   ...|:|...
  Rat   918 PGPGPLLQYLSLPFFREMNVDG--DWPPLEEPTPASPPDFMGSHPCPTSSFLPPPDSPPTNLRAV 980

  Fly  1352 GGPTLIGNGSVAA---VAGGSGTLRRGILRGVV-GVPQPDVTHHTSTVGGSPMQMLHDLHPVNLS 1412
            ...||:|.|..:.   .|....|||..:|.|:: ..|:..:|..:|..|.:..     |.|.:.:
  Rat   981 LPGTLMGVGVSSEPPYTALADWTLRERVLPGLLSAAPRGSLTSQSSGRGSASF-----LRPPSTA 1040

  Fly  1413 AST----LTTSTTLNGSLPTATATLPRQPHGILKDPNRN 1447
            .|.    |:.:.....|..:.....||:.|.:.....||
  Rat  1041 PSAGGSYLSPAPGDTSSWASGPERWPRREHVVTVSKRRN 1079

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653
Ig 197..279 CDD:299845
IG_like 296..376 CDD:214653
Ig 300..361 CDD:299845
Ig 380..454 CDD:299845 22/105 (21%)
IG_like 490..573 CDD:214653 18/94 (19%)
Ig 501..560 CDD:299845 12/70 (17%)
Ig 584..666 CDD:299845 19/93 (20%)
IG_like 585..666 CDD:214653 19/92 (21%)
I-set 678..767 CDD:254352 26/95 (27%)
IGc2 692..757 CDD:197706 22/71 (31%)
Ig 788..849 CDD:143165 8/60 (13%)
Ig 885..960 CDD:143165 19/75 (25%)
FN3 967..1051 CDD:238020 24/102 (24%)
Igsf9NP_001100667.1 IG 28..110 CDD:214652 19/99 (19%)
Ig strand A 136..139 CDD:409353 1/2 (50%)
IG_like 143..223 CDD:214653 20/101 (20%)
Ig strand A' 145..148 CDD:409353 0/2 (0%)
Ig strand B 154..161 CDD:409353 3/12 (25%)
Ig strand C 167..172 CDD:409353 2/4 (50%)
Ig strand C' 175..177 CDD:409353 0/1 (0%)
Ig strand D 183..187 CDD:409353 0/3 (0%)
Ig strand E 189..193 CDD:409353 0/3 (0%)
Ig strand F 202..210 CDD:409353 3/22 (14%)
Ig strand G 213..223 CDD:409353 2/9 (22%)
Ig_3 226..305 CDD:404760 19/93 (20%)
putative Ig strand A 226..230 CDD:409353 1/3 (33%)
putative Ig strand A' 235..239 CDD:409353 0/3 (0%)
putative Ig strand B 241..251 CDD:409353 1/9 (11%)
putative Ig strand C' 267..270 CDD:409353 0/2 (0%)
putative Ig strand D 279..282 CDD:409353 0/2 (0%)
putative Ig strand E 284..290 CDD:409353 0/5 (0%)
putative Ig strand F 297..305 CDD:409353 3/7 (43%)
putative Ig strand G 310..319 CDD:409353 1/8 (13%)
Ig 322..407 CDD:416386 27/128 (21%)
Ig strand A' 324..328 CDD:409353 0/3 (0%)
Ig strand B 333..347 CDD:409353 2/16 (13%)
Ig strand C 353..359 CDD:409353 1/5 (20%)
Ig strand C' 362..364 CDD:409353 0/1 (0%)
Ig strand D 371..374 CDD:409353 0/2 (0%)
Ig strand E 378..382 CDD:409353 3/3 (100%)
Ig strand F 391..399 CDD:409353 4/7 (57%)
Ig 418..503 CDD:416386 26/143 (18%)
Ig strand A 418..421 CDD:409353 0/2 (0%)
Ig strand A' 427..430 CDD:409353 0/2 (0%)
Ig strand B 436..443 CDD:409353 3/33 (9%)
Ig strand C 449..454 CDD:409353 1/4 (25%)
Ig strand C' 457..459 CDD:409353 0/1 (0%)
Ig strand D 462..466 CDD:409353 0/3 (0%)
Ig strand E 469..473 CDD:409353 1/3 (33%)
Ig strand F 482..490 CDD:409353 4/7 (57%)
Ig strand G 493..503 CDD:409353 1/9 (11%)
FN3 508..599 CDD:238020 24/91 (26%)
FN3 625..715 CDD:238020 17/97 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 766..807 10/63 (16%)
PHA03247 <777..1062 CDD:223021 63/316 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 819..846 4/26 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 869..895 4/27 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 942..979 11/36 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1016..1079 12/67 (18%)
PDZ-binding. /evidence=ECO:0000250 1177..1179
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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