DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and CG30350

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster

Alignment Length:	127	Identity:	27/127 - (21%)
Similarity:	56/127 - (44%)	Gaps:	25/127 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1129 AELTEDSSNTPNLVIIGISLAA--------FGFLLVNASLVAWFFVHQRRKKVAETTNQPAKTAT 1185
            |:|||....|..|.:.....||        .|.|:|| .:..|   ||.|:::      ....:|
  Fly    16 AQLTEQERLTAQLKVKERKKAAKAKPKKILGGLLMVN-HMKMW---HQHRERI------KGAIST 70

  Fly  1186 IEMYAPSSYNDTVTGETLSSVSEKSESYSNEGSSQPEYIDEVRKKAASTYLVEGSDMPPPRY 1247
            ::..||:.....:||  ::::.::::::.....:..:.:.|:.:    |....|: :.|.||
  Fly    71 VDAEAPNFQAARITG--VNNLRDEAQTFMKRTKANIQLLVEISR----TMRTHGA-INPFRY 125

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590	12/79 (15%)
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3515
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900