DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and Gm609

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_011244156.1	Gene:	Gm609 / 208166	MGIID:	2685455	Length:	312	Species:	Mus musculus

Alignment Length:	187	Identity:	44/187 - (23%)
Similarity:	64/187 - (34%)	Gaps:	63/187 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   623 NNTSKPGLWGGTVSTLEFRVNVTQEMNGQVYTCQSANEALQRS----AHEAVSLDVLYRPKFVPP 683
            :||.:..:.||.:|..   .|.|...|.:..|.|....:|.::    :|:       |..|.:||
Mouse    29 HNTYERAVLGGNISIF---CNFTSLENVEQITWQKIQGSLPQNIGTYSHK-------YGEKILPP 83

  Fly   684 PSSTAVGVEGESLQVSLQTRANPTPVTYKWTKDGTTIPQDGDHRIFADGGSLNFTRLHRDDAGIY 748
            ..:        .||..:.     .|.||..|..|.|.                      :|...|
Mouse    84 YVN--------RLQCKIL-----EPSTYFMTIQGVTF----------------------EDEACY 113

  Fly   749 SCSAS----NSQGGAT-LNITVVVEYGTTIKSVSENIVVNPGEDAM--LSCTVEGKP 798
            .|..:    .|.||.| |.|..|.|..|.::|.       ||.:.:  |.|:..|||
Mouse   114 KCLFNTFPHGSHGGQTCLTIITVSELVTELRSA-------PGSEDLHSLLCSAVGKP 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845	11/46 (24%)
		IG_like	585..666	CDD:214653	11/46 (24%)
		I-set	678..767	CDD:254352	20/93 (22%)
		IGc2	692..757	CDD:197706	12/68 (18%)
		Ig	788..849	CDD:143165	5/13 (38%)
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
Gm609	XP_011244156.1	Ig1_MRC-OX-2_like	38..132	CDD:319317	29/138 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910