DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and syg-1

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:NP_001123159.1 Gene:syg-1 / 180555 WormBaseID:WBGene00006365 Length:730 Species:Caenorhabditis elegans


Alignment Length:600 Identity:139/600 - (23%)
Similarity:227/600 - (37%) Gaps:148/600 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 IKWQQHATKRRRCRQHWIKHLQLLRLLAVIVLASAPVPSHAQQQKFRTTPHDLQVLEGAEAMMRC 93
            ::||.           |    .||.|..::.....       ||:....|.|.....|..|::.|
 Worm     2 VRWQT-----------W----PLLLLFQLVTCQQL-------QQRIVEAPKDTLAAVGETAILTC 44

  Fly    94 EVANVAGAVQWTKDGFALGF--SAVIPGFPRYSVLGDRKQGIYNLRISNASINDDADYQCQVGPA 156
            .|.:..|.|||.||.|.||.  ...:||..||.::|....|.|||.|||.::.||.|:.||:..:
 Worm    45 RVEHQQGPVQWMKDDFGLGTDRDKPLPGNKRYRMVGSAANGEYNLEISNVTLFDDDDFACQISES 109

  Fly   157 -RLNSAIRANAKLTVI---SPPASIEIKGYSHNSKVEVRENQDLQLKCIVANAKPAAQIVW---- 213
             ...:.:.:.|||||:   :||..::    ||:| ::......:...|:....||...|.|    
 Worm   110 DHAKAVVSSKAKLTVLVRPTPPKIVK----SHHS-LKAIAGDPITQSCLSRKGKPPPTIGWAIAS 169

  Fly   214 ----------------YRGNVEYKPEKREDT----VEEST------------AKRFTTTSSLKLK 246
                            ..|.:..|||..::|    |.|:|            :..::..|:|...
 Worm   170 DEHGKHIVSWLGESRSKFGGIHAKPEISQETVIAHVNETTQVEEGGNNSREDSSIYSIMSNLSFI 234

  Fly   247 PGPDDDYTEYTCQARHKALSPDMPMRATVQLSVLYPPGPPYIEGYSAGE-TLRRGQTVELMCRSR 310
            |.|:||:....|.::|... |:.....:|:||:.|   .|.|....|.: .||...:..|.| :.
 Worm   235 PRPEDDHKYLICISQHMTF-PNKIEVDSVKLSLRY---APQINLTVASKLPLRENGSALLAC-NV 294

  Fly   311 GGNP--PAQLIWYKNGSQIRMAYRTSGRLSENIYTF-TAEAGDNKARFRCEASNVMSQNPLKAEV 372
            ...|  ..::.|||...::|   .|...|     || |.:..|:.....|||:|.:...  :..:
 Worm   295 NAKPLDNVKISWYKGNQKLR---ETGDTL-----TFETLKMEDHNRDIFCEATNEIGTT--RGSI 349

  Fly   373 ELSVLFAPTHVTVMGPTEARVGDIVPLTCTTAPSNPPAEIKWMVGGRQV-----RNATSKTIVSP 432
            :|:|.|....::.....|...||.....|.|. :||...|.|..|....     .|.|.:.:.:.
 Worm   350 KLNVAFGARIMSTSQDKEVNEGDNAFFHCATL-ANPAPAIFWTRGDSDEIIGHGENLTLENVRTW 413

  Fly   433 EGGWTTTSNITAVVEPNKRSLVVICHGLNMQLTENVVSTHTINVLYPPAPPLISGYMEGQIIPA- 496
            :.|   ..|.||.||..::.  ::.|.|:::                 .||.:|  |:.::..: 
 Worm   414 QQG---NYNCTATVEGFRKQ--ILSHYLHIR-----------------GPPTVS--MKDEVSASL 454

  Fly   497 GSVQKLLCVSSGGNPLATLTWYKNDKRIN------------------SVIRAADKSVSAEITILA 543
            ....:::|..||......:.|..|.|.||                  |:::..|..         
 Worm   455 DEATEIICEISGRPKTNNVRWTVNGKEINFNNGRITVHQYPKPYGKESILKIKDLK--------- 510

  Fly   544 NVSDNQAQYRCEASN 558
              .::...|.|.|:|
 Worm   511 --EEDFGVYNCSANN 523

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352 35/99 (35%)
Ig 76..155 CDD:299845 32/80 (40%)
IG_like 186..279 CDD:214653 25/128 (20%)
Ig 197..279 CDD:299845 24/117 (21%)
IG_like 296..376 CDD:214653 20/82 (24%)
Ig 300..361 CDD:299845 16/63 (25%)
Ig 380..454 CDD:299845 18/78 (23%)
IG_like 490..573 CDD:214653 13/87 (15%)
Ig 501..560 CDD:299845 13/75 (17%)
Ig 584..666 CDD:299845
IG_like 585..666 CDD:214653
I-set 678..767 CDD:254352
IGc2 692..757 CDD:197706
Ig 788..849 CDD:143165
Ig 885..960 CDD:143165
FN3 967..1051 CDD:238020
syg-1NP_001123159.1 I-set 24..124 CDD:254352 35/99 (35%)
Ig 30..124 CDD:299845 34/93 (37%)
Ig <151..265 CDD:299845 23/114 (20%)
Ig_2 276..353 CDD:290606 21/87 (24%)
IG_like 283..353 CDD:214653 19/80 (24%)
IG_like 363..427 CDD:214653 18/67 (27%)
Ig_2 368..438 CDD:290606 19/75 (25%)
Ig 440..528 CDD:299845 17/96 (18%)
IG_like 450..535 CDD:214653 13/84 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D141865at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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