DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and Il1rl2

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:NP_598259.2 Gene:Il1rl2 / 171106 RGDID:621782 Length:561 Species:Rattus norvegicus


Alignment Length:674 Identity:129/674 - (19%)
Similarity:207/674 - (30%) Gaps:249/674 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   678 PKFVPPPSSTAVGVEGESLQVSLQTRANPT--PVT-----YKW--TKDGTTIPQDGDHRIFADGG 733
            |.||...:.|.|.:..|.:........|.|  |||     ..|  |...:.|..:...||..|..
  Rat    16 PLFVAAGNCTDVYMHHEMISEGQPFPFNCTYPPVTNGAVNLTWHRTPSKSPISINRHVRIHQDQS 80

  Fly   734 SLNFTRLHRDDAGIYSCSASNSQGGATLNITVVVEYGTTIKSVSENIVVNP----------GEDA 788
            .:.|..|..:|:|||.|...::.....:.|.:.|.......|.:|...:|.          |:..
  Rat    81 WILFLPLALEDSGIYQCVIKDAHSCYRIAINLTVFRKHWCDSSNEESSINSSDEYQQWLPIGKSG 145

  Fly   789 MLSCTV---EGKPLTEEHVKWERVGYDMTVKTSTTFANGTSYLHIKDAKREDVGNFRCVA----- 845
            .|:|.:   |...|  :.:||.: |.: .:|.|..|....:.|.:.:...||.|::.|.|     
  Rat   146 SLTCHLYFPESCVL--DSIKWYK-GCE-EIKVSKKFCPTGTKLLVNNIDVEDSGSYACSARLTHL 206

  Fly   846 -------------------DNRVDN---PTNRDILLIVKFAPEIAKTPTLLRAA--SGTGERGRL 886
                               ..|:.|   |.|..|        |:....||:...  :.|.|...|
  Rat   207 GRIFTVRNYIAVNTKEVGSGGRIPNITYPKNNSI--------EVQLGSTLIVDCNITDTKENTNL 263

  Fly   887 PCRAQGSPKPQFIWRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARNE 951
            .|           ||       :|.|                   :||     ||  |....|  
  Rat   264 RC-----------WR-------VNNT-------------------LVD-----DY--YNDSKR-- 282

  Fly   952 LGEAVETVRLEITSQPDPPLSLNILNVTHDTVTLAWTPGFDGGLKASYRVRYRMADREQYKYIDG 1016
            :.|.:|| .|.:.:.....:::..|.|..:.....:|  ...|:.|:|.:..|.|          
  Rat   283 IQEGIET-NLSLRNHILYTVNITFLEVKMEDYGHPFT--CHAGVSAAYIILKRPA---------- 334

  Fly  1017 LPNSHKLTIGG------LRMNTLYLFS------VMSWNELGQSSYLPDLARAETKEAPPPSHPAS 1069
             |:.....|||      |.::.||:::      |:.:.....::..||..:........|.:|..
  Rat   335 -PDFRAYLIGGLMAFLLLAVSILYIYNTFKVDIVLWYRSTFHTAQAPDDEKLYDAYVLYPKYPRE 398

  Fly  1070 SLGGGPPTTSQTPLGGTSGMLLVGVGAGIVVVLL----------NVFVIGCCLHKRNE------- 1117
            |.|....|                    :|:.:|          .:|:.|     |:|       
  Rat   399 SQGHDVDT--------------------LVLKILPEVLEKQCGYKLFIFG-----RDEFPGQAVA 438

  Fly  1118 ----KRLKRGLELMPAELTEDSSNTPNLVIIGISLAAFGFLLVNASLVAWFFVHQRRKKVAETTN 1178
                :.:|....||              |::....::|.||                        
  Rat   439 SVIDENIKLCRRLM--------------VLVAPETSSFSFL------------------------ 465

  Fly  1179 QPAKTATIEMYAPSSYNDTVTG--ETLSSVSEKSESYSNEGSSQPEYIDEVRKKAASTYLVEGS- 1240
               |..|.|..|  .||..|..  :.:....|:.:.|    |:.||.|..:|:|..:... :|. 
  Rat   466 ---KNLTEEQIA--VYNALVQDGMKVILIELERVKDY----STMPESIQYIRQKHGAIQW-DGDF 520

  Fly  1241 -----------------DMPPPRY 1247
                             .|||.||
  Rat   521 TEQAQCAKTKFWKKVRYHMPPRRY 544

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653
Ig 197..279 CDD:299845
IG_like 296..376 CDD:214653
Ig 300..361 CDD:299845
Ig 380..454 CDD:299845
IG_like 490..573 CDD:214653
Ig 501..560 CDD:299845
Ig 584..666 CDD:299845
IG_like 585..666 CDD:214653
I-set 678..767 CDD:254352 25/97 (26%)
IGc2 692..757 CDD:197706 19/73 (26%)
Ig 788..849 CDD:143165 16/87 (18%)
Ig 885..960 CDD:143165 15/74 (20%)
FN3 967..1051 CDD:238020 16/95 (17%)
Il1rl2NP_598259.2 Ig 26..115 CDD:416386 21/88 (24%)
Ig strand A' 31..35 CDD:409353 1/3 (33%)
Ig strand B 39..44 CDD:409353 0/4 (0%)
Ig strand C 55..59 CDD:409353 0/3 (0%)
Ig strand C' 64..66 CDD:409353 0/1 (0%)
Ig strand D 74..78 CDD:409353 2/3 (67%)
Ig strand E 80..84 CDD:409353 0/3 (0%)
Ig strand F 93..101 CDD:409353 4/7 (57%)
Ig strand G 104..115 CDD:409353 1/10 (10%)
Ig 133..222 CDD:416386 17/92 (18%)
Ig strand A 135..140 CDD:409353 0/4 (0%)
Ig strand B 145..149 CDD:409353 1/3 (33%)
Ig strand C 161..166 CDD:409353 2/4 (50%)
Ig strand C' 169..171 CDD:409353 0/2 (0%)
Ig strand D 176..180 CDD:409353 1/3 (33%)
Ig strand E 182..187 CDD:409353 1/4 (25%)
Ig strand F 196..205 CDD:409353 2/8 (25%)
Ig strand G 208..221 CDD:409353 0/12 (0%)
Ig 230..330 CDD:416386 31/156 (20%)
Ig strand A 230..233 CDD:409353 1/2 (50%)
Ig strand A' 238..241 CDD:409353 1/10 (10%)
Ig strand B 246..255 CDD:409353 2/8 (25%)
Ig strand C 262..268 CDD:409353 4/23 (17%)
Ig strand C' 270..273 CDD:409353 1/21 (5%)
Ig strand E 296..303 CDD:409353 0/6 (0%)
Ig strand G 322..330 CDD:409353 3/7 (43%)
TIR 389..539 CDD:396246 34/222 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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