DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and Il1rl1

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:NP_001020773.1 Gene:Il1rl1 / 17082 MGIID:98427 Length:567 Species:Mus musculus


Alignment Length:481 Identity:107/481 - (22%)
Similarity:156/481 - (32%) Gaps:144/481 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   629 GLWGGTVSTLEFRVNVTQEMNGQVYTCQSANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEG 693
            |||...:.||...:.||:                                     .|.::.|:|.
Mouse     8 GLWALAILTLPMYLTVTE-------------------------------------GSKSSWGLEN 35

  Fly   694 ESLQVSLQTRANPT-PVTYKWTKDGTTIPQDGDHRIFADGGSLNFTRLHRDDAGIYSC--SASNS 755
            |:|.|....|...| ||.:.::....:||....:|||.....|.|.....:|:|||:|  .:.|.
Mouse    36 EALIVRCPQRGRSTYPVEWYYSDTNESIPTQKRNRIFVSRDRLKFLPARVEDSGIYACVIRSPNL 100

  Fly   756 QGGATLNITVVVEYGTTIKSVSENIVVNPGEDAMLSCTVEGK--------PLTEEH-----VKWE 807
            .....||:|:      ..|..|.||     .|.::..||.|.        |..:.:     |:|.
Mouse   101 NKTGYLNVTI------HKKPPSCNI-----PDYLMYSTVRGSDKNFKITCPTIDLYNWTAPVQWF 154

  Fly   808 RVGYDMTVKTSTTFANGTSYLHIKDAKREDVGNFRCVADNRVDNPTNRDILLIVKFA-------- 864
            :   :........|....|||.|.:...:|.|::.| .....:|.||..:.....|.        
Mouse   155 K---NCKALQEPRFRAHRSYLFIDNVTHDDEGDYTC-QFTHAENGTNYIVTATRSFTVEEKGFSM 215

  Fly   865 -PEIAKTPTLLRAASGTGERGRLPCRAQGSPKPQF----IWRQDKKDLPINRTY----------- 913
             |.|...|.........|:...:.|.|.......|    :|:       ||:|.           
Mouse   216 FPVITNPPYNHTMEVEIGKPASIACSACFGKGSHFLADVLWQ-------INKTVVGNFGEARIQE 273

  Fly   914 ---KYEVEERKIDSLTYESTLIVDKVAPADYG-AYECVARNELGEAVETVRLEITSQPDPPLSLN 974
               :.|.....:|.||  |.|.:..|...|.. .|:|:|.|..|....|:||. ..||....|:.
Mouse   274 EEGRNESSSNDMDCLT--SVLRITGVTEKDLSLEYDCLALNLHGMIRHTIRLR-RKQPIDHRSIY 335

  Fly   975 ------------------ILNVTHDTVTLAW----TP---GFDGGLKASYRVRYRM-----ADRE 1009
                              :|.|....|.|.|    ||   ..||.|..:|.:..|:     |...
Mouse   336 YIVAGCSLLLMFINVLVIVLKVFWIEVALFWRDIVTPYKTRNDGKLYDAYIIYPRVFRGSAAGTH 400

  Fly  1010 QYKYI------DGLPN--SHKLTIGG 1027
            ..:|.      |.|.|  .:||.|.|
Mouse   401 SVEYFVHHTLPDVLENKCGYKLCIYG 426

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653
Ig 197..279 CDD:299845
IG_like 296..376 CDD:214653
Ig 300..361 CDD:299845
Ig 380..454 CDD:299845
IG_like 490..573 CDD:214653
Ig 501..560 CDD:299845
Ig 584..666 CDD:299845 7/36 (19%)
IG_like 585..666 CDD:214653 7/36 (19%)
I-set 678..767 CDD:254352 26/91 (29%)
IGc2 692..757 CDD:197706 21/67 (31%)
Ig 788..849 CDD:143165 14/73 (19%)
Ig 885..960 CDD:143165 21/93 (23%)
FN3 967..1051 CDD:238020 23/99 (23%)
Il1rl1NP_001020773.1 Ig 33..97 CDD:416386 20/63 (32%)
Ig strand B 37..42 CDD:409353 2/4 (50%)
Ig strand C 51..55 CDD:409353 2/3 (67%)
Ig strand C' 60..62 CDD:409353 0/1 (0%)
Ig strand D 70..74 CDD:409353 3/3 (100%)
Ig strand E 76..80 CDD:409353 1/3 (33%)
Ig strand F 89..97 CDD:409353 4/7 (57%)
Ig2_IL1R-like 124..210 CDD:409415 18/89 (20%)
Ig strand B 135..139 CDD:409415 0/3 (0%)
Ig strand C 150..154 CDD:409415 1/3 (33%)
Ig strand E 170..174 CDD:409415 3/3 (100%)
Ig strand F 184..189 CDD:409415 1/5 (20%)
Ig strand G 201..204 CDD:409415 0/2 (0%)
Flexible linker. /evidence=ECO:0000250 204..216 1/11 (9%)
Ig <291..324 CDD:416386 10/32 (31%)
Ig strand E 291..294 CDD:409353 1/2 (50%)
Ig strand F 305..310 CDD:409353 2/4 (50%)
Ig strand G 318..321 CDD:409353 0/2 (0%)
TIR 385..540 CDD:396246 11/42 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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