DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP001126

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_322033.4	Gene:	AgaP_AGAP001126 / 1282038	VectorBaseID:	AGAP001126	Length:	276	Species:	Anopheles gambiae

Alignment Length:	219	Identity:	50/219 - (22%)
Similarity:	85/219 - (38%)	Gaps:	38/219 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 TTPHDLQVLEGAEAMMRCEVANVAG-AVQWTKDG----FALGFSAVIPGFPRYSVLGDRK-QGIY 134
            |.|.::..|.|...::.|:|.|:.. .|.|.:..    ..:|         ||:...|:: :.::
Mosquito    37 TVPSNITGLVGKTVLLNCKVKNLGNRTVSWVRHRDIHLLTVG---------RYTYTSDQRFEAMH 92

  Fly   135 N-------LRISNASINDDADYQCQVGPARLNSAIRANAKLTVISPPASIEIKGYSHNSKVEVRE 192
            :       |||..|...|...|:||:.   ....|.....||::.|..  ||.|   ...:.:.:
Mosquito    93 SPHTEEWTLRIRYAQRKDSGIYECQIS---TTPPIGHFVYLTIVEPVT--EING---GPDLFINK 149

  Fly   193 NQDLQLKCIVANA-KPAAQIVWYRGNVEYKPEKREDTVEESTAKRFTTTSSLKLKPGPDDDYTEY 256
            ...:.|.|||..| :|...:||.....:...:.....:...|.|...|||.|.::.....|...|
Mosquito   150 GSTINLTCIVKYAPEPPPAVVWKHNRDDINFDSPRGGISLVTEKGILTTSRLLVQKAIASDSGLY 214

  Fly   257 TCQARHKALSPDMPMRATVQLSVL 280
            ||:       |.....|:|::.:|
Mosquito   215 TCE-------PSNANPASVRVHIL 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352	23/106 (22%)
		Ig	76..155	CDD:299845	21/91 (23%)
		IG_like	186..279	CDD:214653	21/93 (23%)
		Ig	197..279	CDD:299845	21/82 (26%)
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
AgaP_AGAP001126	XP_322033.4	V-set	37..133	CDD:284989	24/107 (22%)
		IG_like	39..121	CDD:214653	20/93 (22%)
		IGc2	150..222	CDD:197706	19/78 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910