DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP001201

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_321956.5	Gene:	AgaP_AGAP001201 / 1281967	VectorBaseID:	AGAP001201	Length:	322	Species:	Anopheles gambiae

Alignment Length:	251	Identity:	63/251 - (25%)
Similarity:	103/251 - (41%)	Gaps:	42/251 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 AMMRCEVANVAG-AVQW--TKDGFALGFSA-VIPGFPRYSVLGDRKQGIYNLRISNASINDDADY 149
            |:::|.|.:... .|.|  .:|...|..:. ...|..|:||:.......::|:|..|...|...|
Mosquito    21 AVLKCRVKHKGDRTVSWMRKRDLHILTSNIYTYTGDQRFSVIHPPDSDDWDLKIEYAQQKDSGIY 85

  Fly   150 QCQVG-PARLNSAIRANAKLTVISPPASIEIKGYSHNSKVEVRENQDLQLKCIVANAKPAAQIVW 213
            :|||. ..::|.|:..:. ...:|..|..:|.|   :.:|.|::...:.|.|:| |.. |:.|.|
Mosquito    86 ECQVNTEPKINLAVYLDV-TDFLSTAARAKIIG---SQEVHVKKGSTISLSCVV-NVH-ASSISW 144

  Fly   214 Y-------------RGNVEYKPEKREDTVEESTAKRFTTTSSLKLKPGPDDDYTEYTCQARHKAL 265
            |             ||.:..:.||.|.          .|:|.|.|......|...|||
Mosquito   145 YVYHGSSIVDFDSARGGISLETEKTEG----------GTSSRLMLTRATLRDSGNYTC------- 192

  Fly   266 SPDMPMRATVQLSVLYPPGPPYIEGYSAGETLRRGQTVELMCRSRGGNPPAQLIWY 321
            .|...:.|:||:.||....|..:: .|:|......||:.|:..|......::||::
Mosquito   193 VPTGAISASVQVHVLNGEHPAAMQ-TSSGVPCPTHQTLILLFVSLNSCNVSKLIFF 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352	21/85 (25%)
		Ig	76..155	CDD:299845	19/70 (27%)
		IG_like	186..279	CDD:214653	27/105 (26%)
		Ig	197..279	CDD:299845	25/94 (27%)
		IG_like	296..376	CDD:214653	6/26 (23%)
		Ig	300..361	CDD:299845	6/22 (27%)
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
AgaP_AGAP001201	XP_321956.5	Ig	9..97	CDD:299845	19/75 (25%)
		IG_like	10..92	CDD:214653	19/70 (27%)
		IG_like	118..206	CDD:214653	27/106 (25%)
		IGc2	126..199	CDD:197706	22/91 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910