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Protein Alignment sns and AgaP_AGAP002104

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_320937.5	Gene:	AgaP_AGAP002104 / 1281351	VectorBaseID:	AGAP002104	Length:	1055	Species:	Anopheles gambiae

Alignment Length:	1271	Identity:	269/1271 - (21%)
Similarity:	416/1271 - (32%)	Gaps:	354/1271 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 SVLYPPGPPYIEGYSAGETLRRGQTVELMCRSR---GGNPPAQLIWYKNGSQIRMAYRTSGRLSE 339
            |:|..|.|.::     .|.: :|...:|.|...   .|:....:||||....|
Mosquito    17 SLLIIPAPLHL-----SEAV-QGTVGQLECNITSPISGDRAILVIWYKGAQTI------------ 63

  Fly   340 NIYTFTAEAGDNKARFRCEASNVMSQNPLKAEVELSVLFAPTHVTVM------GPTEARVGDIVP 398
            ..|||  :|.|.:     |.|:..|.:.......    |.|.....|      .||::.:
Mosquito    64 PFYTF--DARDVR-----EGSHRSSNSSFDGRTN----FYPNRTPAMLEILQTKPTDSGI----- 112

  Fly   399 LTCTTAPSNPPAEIKWMVGGRQVRNATSKTIVSPEGGWTTTSNITAVVEPNKRSLVVICHGLNMQ 463
            ..|.......|           .||              |...:|.:|.|.|..:|
Mosquito   113 YRCRVDFHKSP-----------TRN--------------TRVQLTVIVPPEKLLIV--------- 143

  Fly   464 LTENVVSTHTINVLYPPAPPLISGYMEGQIIPAGSVQKLLCVSSGGNPLATLTWYKNDKRINSV- 527
               :...:|..:.:..|       |.||..|      .:.|:|:||.||..:.|:..:|.||:.
Mosquito   144 ---DEKGSHIRHYILGP-------YNEGATI------NITCISTGGRPLPKVQWWYENKVINNTS 192

  Fly   528 IRAADKSVSAEITI-------LANVSDNQAQYRCEASNSATEIPLFQSTTLSVHFAPETVKIRIE 585
            :..:||.|...:.:       |.:|      :.|:|:|:....|:..|.||.::..|.:|:::.:
Mosquito   193 VVLSDKRVKNTLVLHRLERKHLKSV------FTCQAANNNVTNPISASITLDMNLRPLSVRLQGK 251

  Fly   586 PEELRPGMEATIICDSSSSNPPAKLSWWKDGIPIEGINNTSKPGLWGG-TVSTLEFRVNVTQEMN 649
            ...|.......:.|:...|.|...::|||....:.|.:.|:.|.  |. |||.|.||..:..:
Mosquito   252 NRPLSANHTYDLQCEVLGSRPAPTITWWKGSTQMRGHHETTDPD--GNVTVSILSFRPTIDDK-- 312

  Fly   650 GQVYTCQSANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEGESLQVSLQTRANPTPVTYKWT 714
            |:..:|:         |..||
Mosquito   313 GKYLSCR---------AEMAV-------------------------------------------- 324

  Fly   715 KDGTTIPQDGDHRIFADGGSLNFTRLHRDDAGIYSCSASNSQGGATLNITVVVEYGTTIKSVSEN 779
                 ||..|..    ||..|:          ||...            .|.:||||.....|.
Mosquito   325 -----IPDAGKE----DGWKLD----------IYHVP------------VVTLEYGTNYNYTSS- 357

  Fly   780 IVVNPGEDAMLSCTVEGKPLTEEHVKWERVGYDMTVKTSTTFANGTSYLHIKDAKREDVGNFRCV 844
              :..|.|....|.::..|...: |.|...|.::....|.........|.:::..|...|.:.||
Mosquito   358 --IPEGVDVYFECNIKSNPWVYK-VIWRHYGKELVNNPSEGVTVSNQSLVLQNVSRNRAGQYTCV 419

  Fly   845 ADNRVDNPTNRDILLIVKFAPEIAKTPTLLRAASGTGERGRLPCRAQGSP-KPQFIWR-----QD 903
            ..||..:..:..:.|.:|||| :.:...:.....|..|..::.|..:.:| ...|.|:     .:
Mosquito   420 GSNREGDGESNPVHLDIKFAP-VCRPGLVTTYNVGRNELAKIVCELEANPSNVTFTWKYNTSVSE 483

  Fly   904 KKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARNELGEAVETVRLEI--TSQ 966
            ..|:|.:     ||...:..|:.:     ...|...|||...|..|||:|...|.....:  ..:
Mosquito   484 SLDIPAS-----EVLSDRTKSVAH-----FKPVTEKDYGTLLCWGRNEIGAQTEPCLFNLIPAGK 538

  Fly   967 PDPPLSLNILNVTHDTVTLAWTPGFDGGLKASYRVR-YRMADREQYKYIDGLPNSHKLTIGGLRM 1030
            |||..:..|||.|.|.:.:....|:||||...:::. |.:..|:|...|..  .|....:.||..
Mosquito   539 PDPLSNCTILNQTFDMLQIECLEGYDGGLPQVFQIELYVIGSRQQMTSIKS--TSPAFDLKGLEP 601

  Fly  1031 NTLYLFSVMSWNELGQSSYLPDLARAETKEAPPPSHPASSLGGGPPTTSQ-TPLGGTSGMLLVGV 1094
            ...|...:.:.|..|.|.  |...:|.|.:.|......|.:  .||...| .|..||    |:||
Mosquito   602 GVGYNIILTAKNSKGSSD--PTYLQAFTLKNPEKQTDLSLV--YPPALLQIKPFIGT----LLGV 658

  Fly  1095 GAGIVVVLLNVFVIGCCLHKRNEKRLKR--GLELMPAELTEDSSNTPNLVIIGISLAAFGFLLVN 1157
            .|.|:.:   ..:|.|....|......|  |..:.    |.|:|        |||.:     :.:
Mosquito   659 VAAIISI---ASIIVCVTRLRGSAGRDRDCGSNMS----TNDAS--------GISQS-----IPD 703

  Fly  1158 ASLVAWFFVHQRRKKVAETTNQPAKTATIEMYAPSSYNDTVTGETLSSVSEKSESYSNEGSSQPE 1222
            |.|.        |::...:.:...|...|...|...:        |....||:..:.|..:....
Mosquito   704 ADLA--------REQCNGSIDSIEKNPDIIPQAKLLH--------LLKEDEKAFEWLNNAAHPRL 752

  Fly  1223 YIDEVRKKAASTYLVEGSDMPPPRYQKDGTLPVIYPNNVVNACTLPHPRHNNGSAAIHMTRDDQM 1287
            |     ..||......|..:||      ......|......|  |...............:..|.
Mosquito   753 Y-----ATAAMAEQQSGGLLPP------SAAAATYDTRAFYA--LARDAQQQQQQQQQQQQQQQN 804

  Fly  1288 LISKGVYIPSPSPAPPPDGSYYNMNSDRYLSYPPMEYPAALDFTAQPMPM-------AHLQPMTV 1345
            .:.:.||     |....||.          ||.||.      .|....|:       .|...:|.
Mosquito   805 CMQQNVY-----PVASSDGQ----------SYIPMH------GTIISTPIVGGYGSDGHKHDLTY 848

  Fly  1346 TSLATNGGPTLIGNGSVAAVAGGSG--TLRRG----ILRGVVGVP-QPDVTHHTSTVGGSPMQML 1403
            ..|:.:||            .||:|  .|..|    .:...:|.| |.|:.....|: .:.:.:.
Mosquito   849 ADLSISGG------------GGGAGMPKLNPGQPQMYVSATLGRPRQSDIKRSEPTI-YAQIDLA 900

  Fly  1404 HDLHPVNLSASTLTTSTTLNGSLPTATAT-LPRQPHGILKDPNRNKQQQQQQQQQQQQQQLQHQQ 1467
            |  || .:.::.|..:.....|:|.:.|| ||.....:|        |||||.....|..||...
Mosquito   901 H--HP-GVHSTNLVYTNAPRHSIPISHATGLPVSGAHLL--------QQQQQHTVPVQSPLQRAP 954

  Fly  1468 QLLNASLV---------GVGVPVSAPLGSLQILNLP 1494
            .....||.         |..:|||   |.....|.|
Mosquito   955 DSGQPSLTERYPPPPLFGGSLPVS---GQQHCANEP 987

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.