DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sns and AgaP_AGAP012059

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:XP_320464.4 Gene:AgaP_AGAP012059 / 1280607 VectorBaseID:AGAP012059 Length:464 Species:Anopheles gambiae


Alignment Length:492 Identity:115/492 - (23%)
Similarity:174/492 - (35%) Gaps:125/492 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   678 PKFVPPPSSTAVGVEGESLQVSLQTR-----ANP-------TPVTYK------------------ 712
            |:....|....:.|....||.:|.|.     .||       .|.|.|                  
Mosquito     3 PQMAASPVVVQLAVAFVVLQAALGTNRQIVTGNPAAGSFLSVPTTVKRYENDTVLLPCYHNAPYR 67

  Fly   713 ---WTKDGTTIPQDGDHRIFAD-----------GGSLNFTRLHRDDAGIYSCSASNSQGGATLNI 763
               |::|...:.   |.| :.|           .|||..|.:..||.|.|:|......|.|:.:.
Mosquito    68 YVRWSRDDLLLV---DSR-YPDLRTPPRMRLWPNGSLEVTEVQTDDTGDYTCEIMTDGGKASQHH 128

  Fly   764 TVVVEYGTTIKSVSEN-IVVNPGEDAMLSCTVEGKPLTEEHVKW-ERVGYDMTVKTSTTFANGTS 826
            .:.|::..|.....|: |.:..|:.....|.|.|.|  :.:||| .:||:  ||:....|.|...
Mosquito   129 AIEVQFQATAAIYPEDPIDIRVGQILEAVCQVTGMP--QPYVKWMMQVGH--TVEPLPHFRNERK 189

  Fly   827 YLHIKDAKREDVGNFRCVADNRVDNPTNRDILLIVKFAPEI-AKTPTLLRAASGTGERGRLPCRA 890
             |::....|...|..:|.|.|.|..|.:..:.:||.|.||| .|:||:   .:..||.|.|.|..
Mosquito   190 -LNVLIEDRTFSGPLQCTATNGVGEPASAAVEVIVNFVPEIEVKSPTV---HTRIGETGLLECLV 250

  Fly   891 QGSPKPQFIW-----------RQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAY 944
            ...|.....|           |..|.|..:.:...|.|:..:         |.:..:..||.|.|
Mosquito   251 TAHPAASIHWFHHGLPVVYDRRIVKLDTLVTKHQYYTVQRHQ---------LAIRSLRDADLGQY 306

  Fly   945 ECVARNELGEAVETVRLEITSQP-----------DPPLSLNILNVTHDTVTLAWTPGFDGGLKAS 998
            ||.|.|.:|  :...:||:|.:|           ..|...|.:..|.....|           ..
Mosquito   307 ECKAGNRVG--IAGAQLELTGRPMVASFKPAAEMSSPTRHNFIWQTESHSPL-----------IE 358

  Fly   999 YRVRYRMADR-----------EQYKYID---------GLPNSHKLTIGGLRMNTLYLFSVMSWNE 1043
            |::::|....           :|:.:.:         |..:|...|:.||:..::|...|:|.|.
Mosquito   359 YKLKFRRVPSGNVTPGRRTLPQQFAWKELIIPSDGSYGPLHSSGYTLEGLQPTSVYEVIVLSRNR 423

  Fly  1044 LGQS--SYLPDLARAETKEAPPPSHPASSLGGGPPTT 1078
            .|.|  |.:...|.....|..|.|...:|......||
Mosquito   424 YGWSDPSNILRFATGGEVEIEPGSEADTSSSSSVQTT 460

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653
Ig 197..279 CDD:299845
IG_like 296..376 CDD:214653
Ig 300..361 CDD:299845
Ig 380..454 CDD:299845
IG_like 490..573 CDD:214653
Ig 501..560 CDD:299845
Ig 584..666 CDD:299845
IG_like 585..666 CDD:214653
I-set 678..767 CDD:254352 28/132 (21%)
IGc2 692..757 CDD:197706 23/108 (21%)
Ig 788..849 CDD:143165 19/61 (31%)
Ig 885..960 CDD:143165 19/85 (22%)
FN3 967..1051 CDD:238020 20/116 (17%)
AgaP_AGAP012059XP_320464.4 IG_like 45..132 CDD:214653 19/90 (21%)
Ig 56..125 CDD:299845 15/72 (21%)
IG_like 149..223 CDD:214653 22/78 (28%)
Ig 158..222 CDD:299845 21/68 (31%)
I-set 227..324 CDD:254352 30/110 (27%)
IGc2 240..315 CDD:197706 21/83 (25%)
FN3 <348..437 CDD:238020 17/99 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.