DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP009253

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_320040.3	Gene:	AgaP_AGAP009253 / 1280215	VectorBaseID:	AGAP009253	Length:	258	Species:	Anopheles gambiae

Alignment Length:	254	Identity:	58/254 - (22%)
Similarity:	94/254 - (37%)	Gaps:	55/254 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 IVLASAPVPSHAQQQKFRTTPHD------------LQVLEGAEAMMRCEVANVAG-AVQWTKDG- 108
            :.:|..|.|..:.|...|.||.|            :..|.|..|.:.|.|.|:.. .|.|.:..
Mosquito    27 VPMALRPSPPSSSQSNLRRTPLDRGPHFDLSASKNITALVGKTAYLNCRVKNIGNKTVSWVRHRD 91

  Fly   109 ---FALGFSAVIPGFPRYSVLGDRK-QGIYN-------LRISNASINDDADYQCQVGPARLNSAI 162
               ..:|         |::...|:: |.::|       |:|......|...|:||:.   ....:
Mosquito    92 IHLLTVG---------RFTYTSDQRFQAVHNPQTDDWSLQIRYPQKRDTGVYECQIS---TTPPV 144

  Fly   163 RANAKLTVISPPASIEIKGYSHNSKVEVRENQDLQLKCIVANA-KPAAQIVWYRGN-VEYKPEKR 225
            ..:..|.|:.|..:  |.|.   ..:.:.....:.|.|||.|: :|.:.|.|...| |..:.|..
Mosquito   145 GHSMFLAVVEPITT--IVGV---PDLYINTGSTVNLTCIVRNSPEPPSTIFWTHNNQVSGEGEIN 204

  Fly   226 EDT----VEESTAKRFTTTSSLKLKPGPDDDYTEYTCQARHKALSPDMPMRATVQLSVL 280
            .|:    |...|.|...|||.|.::.....|..:|.|       ||.....:|:.:.:|
Mosquito   205 YDSPRGGVSVITEKGELTTSYLLIQRARTTDSGKYVC-------SPSNADPSTINVHIL 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352	24/121 (20%)
		Ig	76..155	CDD:299845	22/103 (21%)
		IG_like	186..279	CDD:214653	25/98 (26%)
		Ig	197..279	CDD:299845	25/87 (29%)
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
AgaP_AGAP009253	XP_320040.3	IG_like	59..147	CDD:214653	19/99 (19%)
		Ig	62..143	CDD:299845	19/92 (21%)
		IG_like	163..255	CDD:214653	25/98 (26%)
		IGc2	170..246	CDD:197706	24/82 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910