DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP009183

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_319953.4	Gene:	AgaP_AGAP009183 / 1280143	VectorBaseID:	AGAP009183	Length:	317	Species:	Anopheles gambiae

Alignment Length:	223	Identity:	51/223 - (22%)
Similarity:	77/223 - (34%)	Gaps:	80/223 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 FRTTPHDL---QVLEGAEAMMRCEVANVA-GAVQW--TKDGFALGFSAVIPGFPRYSVLGDRKQG 132
            |.|..|..   ||  |:.|::.|.|.|:. |.|.|  .||     :..:..||..||  .|.:..
Mosquito    91 FETDNHTTIASQV--GSIAVLPCAVRNIGEGVVSWIRRKD-----YHLLTIGFTTYS--SDERFN 146

  Fly   133 I--------YNLRISNASINDDADYQCQVGPARLNSAIRANAKLTVISPPASIEIKGYSHNSKVE 189
            |        :.|:|....:.|...|:|||.                ..||.||.:|.....:|.|
Mosquito   147 IIHSEDTEEWPLQIKYVQLRDAGLYECQVS----------------THPPTSIFVKLDVVEAKAE 195

  Fly   190 V--------RENQDLQLKC-IVANAKPAAQIVWYRGN--VEYKPEKREDTVEESTAKRFTTTSSL 243
            :        :....|:|.| :|.:.:|...|.||..|  :.|...:..:...|:
Mosquito   196 IFGPSEKYLKPGSMLRLTCRVVQSNEPPLYIFWYHNNRMINYDAHRGVNVSTEA----------- 249

  Fly   244 KLKPGPDDDYTE-------------YTC 258
                  |:.|:|             |:|
Mosquito   250 ------DNRYSELVISHTNTLNSGNYSC 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352	28/109 (26%)
		Ig	76..155	CDD:299845	27/92 (29%)
		IG_like	186..279	CDD:214653	18/97 (19%)
		Ig	197..279	CDD:299845	15/78 (19%)
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
AgaP_AGAP009183	XP_319953.4	IG_like	102..189	CDD:214653	30/111 (27%)
		Ig	104..189	CDD:299845	28/107 (26%)
		IG_like	199..276	CDD:214653	16/90 (18%)
		Ig	210..275	CDD:143165	16/79 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910