DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP009829

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_318941.4	Gene:	AgaP_AGAP009829 / 1279247	VectorBaseID:	AGAP009829	Length:	284	Species:	Anopheles gambiae

Alignment Length:	181	Identity:	49/181 - (27%)
Similarity:	73/181 - (40%)	Gaps:	35/181 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 LKAEVELSVLFAPTHVTVMGPTEARVGDIVPLTCTTAPSNPPAE---IKWMVGGRQVRNATSKTI 429
            |:...:|.:......|:|  |...|.||...|.|......  ||   :||..|.|:....|.|.|
Mosquito     1 LRISADLVITLKDVRVSV--PVAIRRGDNANLICHYDMEG--AELYSVKWYKGKREFFRYTPKEI 61

  Fly   430 ----------VSPEGGWTTTSNITAV-VEP---NKRSLVVICHGLNMQLTENVVSTHTINVL-YP 479
                      :|.|...:..|::|.| |||   .|.|..|   ..::...:.::.:..:.|: .|
Mosquito    62 PALKSFVVAGLSVERPLSNGSHLTLVAVEPAATGKYSCEV---SADLPSFDTMIVSSEMEVVDVP 123

  Fly   480 PAPPLISG----YMEGQIIPAGSVQKLLCVSSGGNPLATLTWYKNDKRINS 526
            ...|||:|    |..|.::...      |.|....|.|.|||..:||:||:
Mosquito   124 VTKPLITGIKQFYRIGDVVLGN------CTSYNSKPAANLTWLLDDKKINA 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653	2/7 (29%)
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845	27/90 (30%)
		IG_like	490..573	CDD:214653	12/37 (32%)
		Ig	501..560	CDD:299845	11/26 (42%)
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
AgaP_AGAP009829	XP_318941.4	IG_like	19..102	CDD:214653	26/87 (30%)
		Ig	28..102	CDD:143165	22/78 (28%)
		Ig	141..211	CDD:299845	11/34 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910