DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP010748

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_318565.4	Gene:	AgaP_AGAP010748 / 1278920	VectorBaseID:	AGAP010748	Length:	152	Species:	Anopheles gambiae

Alignment Length:	188	Identity:	63/188 - (33%)
Similarity:	77/188 - (40%)	Gaps:	45/188 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1361 SVAAVAGGSGTLRRGILRGVVGVPQPDVTHHT-STVGGSPMQMLHDLHPVNLSASTLTTSTTLNG 1424
            ||......|.|||| :.|.:  ||.||||||| ...||..    ||    :.|.||.....:||.
Mosquito     4 SVGPTESSSETLRR-VARTM--VPPPDVTHHTHHRTGGQQ----HD----SSSLSTTLPFGSLNA 57

  Fly  1425 SLPTATATLPRQPHGILKDPNRNKQQQQQQQQQ-----QQQQQLQHQQQLLNASLVGVGVPVSAP 1484
            |:..|..:.|:||.|||||..|:..........     ||||||   ..:.|.|.:.....|:.|
Mosquito    58 SISQAVQSTPKQPQGILKDAKRSNSSASGSHTYSSLPLQQQQQL---YSIHNPSPIPSDQYVAGP 119

  Fly  1485 LGSLQILNLPPASGGLGNNLLMTTNAFDPTTVGLSSFGAVSQAGGIPVAYTDADGHLV 1542
            .|.|.....||||..|.:.                         .:.|.|||:|||||
Mosquito   120 SGLLMGAYDPPASSSLASY-------------------------NVSVGYTDSDGHLV 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
AgaP_AGAP010748	XP_318565.4	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910