DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sns and AgaP_AGAP007759

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_317756.4	Gene:	AgaP_AGAP007759 / 1278206	VectorBaseID:	AGAP007759	Length:	238	Species:	Anopheles gambiae

Alignment Length:	191	Identity:	46/191 - (24%)
Similarity:	71/191 - (37%)	Gaps:	32/191 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 PHDLQVLEGAEAMMRCEVANVAG-AVQWTKDG----FALGFSAVIPGFPRYSVLGDRKQGIYNLR 137
            |.::....|..|.:.|.|..:.. :|.|.:..    .:.| :||.....|:.|:...|...:.|:
Mosquito     9 PRNITTRVGQTAFINCRVEQMGDKSVSWIRKRDLHILSAG-TAVYTSDERFQVIRSDKAENWTLQ 72

  Fly   138 ISNASINDDADYQCQVG-PARLNSAIRAN---AKLTVISPPASIEIKGYSHNSKVEVRENQDLQL 198
            |..|...|...|:|||. ..:::.|.|.|   ||..::.|            :.:.|:....:.|
Mosquito    73 IKFAQQRDSGIYECQVNTEPKMSMAFRLNVVEAKAIILGP------------TDLYVKMGSVVTL 125

  Fly   199 KCIVANA-KPAAQIVWYRGNVEYKPEKREDTVEESTAKRFTTTSSLKLKPGPDDDYTEYTC 258
            .||::.. .....|.||||       |..|.  .....|....|.||:......|...|||
Mosquito   126 TCIISQGPHDLGTIYWYRG-------KYADA--GHVLWRSNYCSMLKILDAKLSDSGNYTC 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352	26/100 (26%)
		Ig	76..155	CDD:299845	21/82 (26%)
		IG_like	186..279	CDD:214653	19/74 (26%)
		Ig	197..279	CDD:299845	18/63 (29%)
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
AgaP_AGAP007759	XP_317756.4	IG_like	9..102	CDD:214653	23/93 (25%)
		Ig	12..88	CDD:299845	18/76 (24%)
		IG_like	112..191	CDD:214653	20/87 (23%)
		Ig_3	117..177	CDD:290638	17/68 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910