DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP005849

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_315876.4	Gene:	AgaP_AGAP005849 / 1276518	VectorBaseID:	AGAP005849	Length:	828	Species:	Anopheles gambiae

Alignment Length:	182	Identity:	50/182 - (27%)
Similarity:	76/182 - (41%)	Gaps:	20/182 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   780 IVVNPGEDAMLSCTVEGKPLTEEHVKWERVGYDMTVKTSTTFANG----TSY----LHIKDAKRE 836
            |:|:.|....|.|...|.|  ..||:|.|.       ...|.:||    ||.    |:|....|.
Mosquito   279 IIVHEGTHLRLRCAATGTP--RPHVEWRRA-------DGKTISNGAWEATSMAGHTLNITKINRV 334

  Fly   837 DVGNFRCVADNRVDNPTNRDILLIVKFAPEIAKTPTLLRAASGTGERGRLPCRAQGSPKPQFIWR 901
            .:|.:.|:|||.:..|.|:...:.|.|.|.|.....:..|.:|:  .....|..:..|:....|.
Mosquito   335 HMGAYHCLADNGISPPANQTFNIEVHFPPLIRVRNQMAYAVNGS--TVTFVCEIEAFPEALKYWE 397

  Fly   902 QDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARNELG 953
            :......:....|:::|.. .|.......|.:..:.|:|:|.|.|||:||||
Mosquito   398 RFPGGRLLEPGDKFQMETH-YDGYKSVMRLNITNIRPSDFGEYHCVAKNELG 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165	21/68 (31%)
		Ig	885..960	CDD:143165	18/69 (26%)
		FN3	967..1051	CDD:238020
AgaP_AGAP005849	XP_315876.4	Collagen	140..200	CDD:189968
		IG_like	277..359	CDD:214653	26/88 (30%)
		IGc2	283..348	CDD:197706	22/73 (30%)
		Ig	362..456	CDD:299845	22/90 (24%)
		IG_like	373..456	CDD:214653	20/79 (25%)
		OLF	542..787	CDD:280371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910