DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and Il1r2

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:NP_446405.1 Gene:Il1r2 / 117022 RGDID:621147 Length:416 Species:Rattus norvegicus


Alignment Length:388 Identity:81/388 - (20%)
Similarity:142/388 - (36%) Gaps:92/388 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   652 VYTCQSANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEGESL----------QVSLQTRANP 706
            |:|.:.:...:....|..:..|..:|.:    ...:.:.:|||.:          ..|..:|:..
  Rat    20 VHTGRVSESPVTSEKHPVLGDDCWFRGR----DFKSELRLEGEPVVLRCPLVPHSDTSSSSRSLL 80

  Fly   707 TPVTYKWTKDGTT--IPQDGDHRIFADGGSLNFTRLHRDDAGIYSCSASNSQGGATLNITV---- 765
            |     |:|..::  ||.| :.|::....:|......:.|:|.|.|:..|:.....:::.:    
  Rat    81 T-----WSKSDSSQLIPGD-EPRMWVKDDTLWVLPAVQQDSGTYICTFRNASHCEQMSLELKVFK 139

  Fly   766 -------VVEYGTTIKSVSENIVVNPGEDAMLSCTVEGKPLTEEHVKWERVGYDMTVKTSTTF-- 821
                   :|.|.......|..::|.|.....:|...:||      ::|.: |..:..|.:..|  
  Rat   140 NTEASFPLVSYLQISALSSTGLLVCPDLKEFISSRTDGK------IQWYK-GSILLDKGNKKFLS 197

  Fly   822 ANGTSYLHIKDAKREDVGNFRCV---------------ADNRVDNPTNRDILLIVKFAPEIAKTP 871
            |...:.|.|.:....|.|.:|||               .:.||...|...|.:|:.   .:...|
  Rat   198 AGDPTRLLISNTSMGDAGYYRCVMTFTYEGKEYNITRNIELRVKGITTEPIPVIIS---PLETIP 259

  Fly   872 TLLRAASGTGERGRLPCR---AQGSPKPQFIWRQDKKDL-----PINRT-----YKY-EVEERKI 922
            ..|      |.|..:||:   ..|:.....:|.......     |..|.     ::| |.:|..:
  Rat   260 ASL------GSRLIVPCKVFLGTGTSSNTIVWWMANSTFISVAYPRGRVTEGLHHQYSENDENYV 318

  Fly   923 DSLTYESTLIVDKVAPADYGA-YECVARNELG-EAVETVRLEITSQPD-----PPLSLNILNV 978
                 |.:||.|.|...|... ::|||.|... :::.|...|::|...     .||||.||.|
  Rat   319 -----EVSLIFDPVTKEDLNTDFKCVATNPRSFQSLHTTVKEVSSTFSWGIALAPLSLIILVV 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653
Ig 197..279 CDD:299845
IG_like 296..376 CDD:214653
Ig 300..361 CDD:299845
Ig 380..454 CDD:299845
IG_like 490..573 CDD:214653
Ig 501..560 CDD:299845
Ig 584..666 CDD:299845 2/13 (15%)
IG_like 585..666 CDD:214653 2/13 (15%)
I-set 678..767 CDD:254352 18/111 (16%)
IGc2 692..757 CDD:197706 18/76 (24%)
Ig 788..849 CDD:143165 15/77 (19%)
Ig 885..960 CDD:143165 20/90 (22%)
FN3 967..1051 CDD:238020 7/17 (41%)
Il1r2NP_446405.1 PHA02826 38..240 CDD:165173 40/218 (18%)
Ig 44..137 CDD:299845 19/102 (19%)
Ig 148..242 CDD:299845 22/100 (22%)
I-set 249..343 CDD:254352 23/107 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 396..416
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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