DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and AgaP_AGAP013021

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_003437195.1	Gene:	AgaP_AGAP013021 / 11175855	VectorBaseID:	AGAP013021	Length:	275	Species:	Anopheles gambiae

Alignment Length:	262	Identity:	58/262 - (22%)
Similarity:	90/262 - (34%)	Gaps:	60/262 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   473 TINV-----LYPPAPPLISGYMEGQIIPAGSVQKLLCVSSGGNPLATLTWYKNDKRINSVIRAAD 532
            |:||     .|......::.|.|..::|    ..|..||.      .:|:.|.|.:|...|:...
Mosquito     4 TVNVQLVLRKYVERGSAVALYCENDVLP----DILYKVSD------HVTFLKEDNKIFEYIKGRS 58

  Fly   533 ---------------KSVSAEITILANVS-DNQAQYRCEASNSATEIPLFQSTT----LSVHF-- 575
                           |.|:.....|.|:. |....|.||.|   |:.|:|...:    |.|..
Mosquito    59 PPYRNFSIPGAEIDWKKVTPSTLTLKNLDYDASGSYYCEVS---TDTPIFTKASNDEVLHVMLPQ 120

  Fly   576 -APETVKIRIEPEELRPGMEATIICDSSSSNPPAKLSWWKDGIPIEGINNTSKPGLWGGTVSTLE 639
             .|.|  |....::|..|......|.:|.:.|...::|..:|.|.|    |.|......:.|.|.
Mosquito   121 KGPPT--IEFAKKQLYYGDMLIANCTTSRARPSPHITWLINGKPGE----TRKSHRVFASYSQLS 179

  Fly   640 FRVNVTQEMNGQV----YTCQSANEALQRSAHE-------AVSLDVLYRPKFVPPPSSTAVGVEG 693
            .|  :|:.:...|    .||.:...|......:       .:.||:....:..|.||.:.:...|
Mosquito   180 IR--ITEALTNNVGRIEITCLATIPAHVEPGEQYADYKTSLIKLDIEQNDQTSPQPSMSGMAAFG 242

  Fly   694 ES 695
            .|
Mosquito   243 NS 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653	23/102 (23%)
		Ig	501..560	CDD:299845	17/74 (23%)
		Ig	584..666	CDD:299845	19/85 (22%)
		IG_like	585..666	CDD:214653	19/84 (23%)
		I-set	678..767	CDD:254352	5/18 (28%)
		IGc2	692..757	CDD:197706	2/4 (50%)
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
AgaP_AGAP013021	XP_003437195.1	Ig	124..204	CDD:299845	20/87 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910