DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and LOC108648322

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:XP_017952078.1 Gene:LOC108648322 / 108648322 -ID:- Length:623 Species:Xenopus tropicalis


Alignment Length:736 Identity:147/736 - (19%)
Similarity:250/736 - (33%) Gaps:225/736 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   596 TIICDSSSS---NPPAKLSWWKDGIPIEGINNTSKPGLWGGTVSTLEFRVNVTQEMNGQVYTCQS 657
            |:.|:.|||   .||  ..|:|||:.:|              ....::.:...::.:..||.|:|
 Frog    41 TLTCNVSSSAQGEPP--YFWYKDGVRME--------------TKQQKYTIFNAKKSDSGVYQCKS 89

  Fly   658 ANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEGESLQVSLQTRANPTPVTYKWTKDGTTIPQ 722
            .:.....|....:|.|  |....|||     ...||::||||.        ..|...|..|....
 Frog    90 HSSDRSDSVTLTI
SDD--YLSLKVPP-----FVFEGDNLQVSC--------AGYPGYKADTAKLN 139

  Fly   723 DGDHRI-FADGGSLNFTRLHRDDAGIYSCSAS--------NSQGGATLNITVVVEYGTTIKSVSE 778
            .|:..| .:..|:.||.|:....:|.|.|..:        |.:....:::..:.. ...||..::
 Frog   140 KGNQLIGSSPSGNFNFGRVTMATSGSYICYRAVKHHLIYYNQKSSVYISVKELFS-SPQIKVSTD 203

  Fly   779 NIVVNPGEDAMLSCTVEGKP---LTEEHVKWERVGYDMTVKTSTTFANGTSYLHIKDAKREDVGN 840
            .  |..|:...::|..|..|   .||....:.|.|:::     ..|:....| .:..|:.||.|.
 Frog   204 Q--VTEGDRMTITCDTELSPHRETTELQFAFYRNGHNV-----QGFSLSNQY-GVSSAQLEDSGY 260

  Fly   841 FRC-------VADNRVDNPTNRDILLIVKFAPEIAKTPTLLRAASG---TGERGRLPCRAQ-GSP 894
            :.|       :.:.:.|   .:.|.:..|   ::|.....|..|.|   .||:..:.|..: |..
 Frog   261 YTCEIRAQSGIVNKKSD---RKSIQIRTK---KLAGVRVRLEPAGGQVIAGEKLEILCSVEKGMG 319

  Fly   895 KPQFIWRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGA-YEC-VARNELGEAVE 957
            ..::.|  .|:...|..|.:....|::         .:.:.|: .|||. |:| :.|...||::.
 Frog   320 LLRYSW--CKQPTLICNTKEAAAPEQR---------FVAESVS-EDYGGEYQCIITRTATGESIR 372

  Fly   958 TVRLEITSQPDPPLSLNILNVTHDTVTLAWTPGFDGGLKASYRVRYRMADREQYKYIDGLPNSHK 1022
            :..:.|:.| :|.....|            ||               ..|....|..|.|..:..
 Frog   373 SANISISVQ-EPVADARI------------TP---------------EEDELAVKVEDNLCLTCS 409

  Fly  1023 LTIGGLRMNTLYLFSVMSWNELGQSSYLPDLARAETK----EAPPPSHPASSLGGGPPTTSQTPL 1083
            :..|   .|.|:|: :.:...:|..|.|..: |...|    |:....|                 
 Frog   410 VAKG---TNPLFLW-IHNNKTIGHESVLYQV-RESGKVLCIESAQLQH----------------- 452

  Fly  1084 GGT---------SGMLLVGVGAGIVVVLLNVFVIGCCLHKRNEKRLKRGLELMPAELTEDSSNTP 1139
            .||         |...:..|.:.||.:.:                               |.||.
 Frog   453 AGTYWCEVRNQLSSNRIFTVTSNIVTISI-------------------------------SGNTY 486

  Fly  1140 NLVIIGISLAAFGFLLVNASLVAWFFVHQRRKKVAETTNQPAKTATIEMYAPSSYNDTVTGETLS 1204
            ..|::||.::....|||.|.:|..:          .:|.....|.   .:.|:|...:||     
 Frog   487 RYVVMGIGISLASLLLVTAIVVFKY----------RSTMASCFTC---CHFPTSSGGSVT----- 533

  Fly  1205 SVSEKSESYSNEGSSQPEYIDEVRKKAASTYLVEGSDMPP----PRYQ----KDGTLPVIYPNNV 1261
                     .::..|.|      |::.|:.|:  .:|..|    |.|.    :||.....|.|..
 Frog   534 ---------KDQNGSDP------RQQVANLYI--PNDGKPEEEQPEYGNIVIQDGEDECYYMNYD 581

  Fly  1262 VNACTLPHPRHNNGSAAIHMT 1282
            ..|.:|  |::|....::..|
 Frog   582 PTASSL--PKNNYDKVSVTYT 600

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653
Ig 197..279 CDD:299845
IG_like 296..376 CDD:214653
Ig 300..361 CDD:299845
Ig 380..454 CDD:299845
IG_like 490..573 CDD:214653
Ig 501..560 CDD:299845
Ig 584..666 CDD:299845 16/72 (22%)
IG_like 585..666 CDD:214653 16/72 (22%)
I-set 678..767 CDD:254352 22/97 (23%)
IGc2 692..757 CDD:197706 19/73 (26%)
Ig 788..849 CDD:143165 14/70 (20%)
Ig 885..960 CDD:143165 16/77 (21%)
FN3 967..1051 CDD:238020 14/83 (17%)
LOC108648322XP_017952078.1 Ig 23..102 CDD:386229 17/76 (22%)
Ig 200..283 CDD:386229 18/93 (19%)
Ig_3 398..462 CDD:372822 16/85 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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