DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and LOC101734363

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:XP_031749262.1 Gene:LOC101734363 / 101734363 -ID:- Length:829 Species:Xenopus tropicalis


Alignment Length:971 Identity:201/971 - (20%)
Similarity:315/971 - (32%) Gaps:309/971 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 FRTTPHDLQVLE-----------GAEAMMRCEVANVAGAVQWTKDGFALGFSAVIPGFP------ 121
            |...|..:.|||           |:..::.|.              |.:..|.::|.|.      
 Frog     9 FLLVPGAVSVLEVFAPPTQQTFLGSNVLLPCT--------------FQVENSQILPNFLAVFWYI 59

  Fly   122 ------RYS----------VLGDRK---QGIYNLRISNASINDDADYQCQVGPARLNSAIRANAK 167
                  ||.          |..|.|   ||..::.:||.:|:|...|:|.|    ::|..|....
 Frog    60 GDKEIFRYDNKGKSISHSRVTADEKGFPQGNASITLSNVAISDQGTYRCLV----IHSPSRKEKD 120

  Fly   168 LTVISPPASIE-IKGYSHNSKVEVRENQDLQLKCIVANAKPAAQIVWYRGNVEYKPEKREDTVEE 231
            :||     .:: |.|.....|..:::.:.: |:|:|.:..|....|.:..|.:..|.....|..|
 Frog   121 ITV-----KVQAIPGVHIMKKALIKQEEGV-LQCLVTDYYPPLVTVTWLLNGKPSPGSVLGTPRE 179

  Fly   232 STAKRFTTTSSLKLKPGPDDDYTEYTCQARHKALSPDMPMRATVQLSVLYPPGPPYIEGYSAGET 296
            :....|...|:|.|.|..........||.:|::    .|........|:|               
 Frog   180 NMDGTFRVNSTLTLSPSETQSDLVIGCQVQHES----HPQPLADSFKVVY--------------- 225

  Fly   297 LRRGQTVELMCRSRGGNPPAQLIWYKNGSQIRM-AYRTSGRLSENIYTFTAEAGDNKARFRCEAS 360
                           |.||:          :|| :.:..|.| |.|             |.||||
 Frog   226 ---------------GVPPS----------VRMFSSKVEGHL-EQI-------------FVCEAS 251

  Fly   361 NVMSQNPLKAEVELSVLFAPTHVTVMGPTEARVGDIVPLTCTTAPSNPPAEIKWMVGGRQVRNAT 425
            .                |:|                           .|.:|||:|.|.:|....
 Frog   252 G----------------FSP---------------------------EPVQIKWLVDGMRVEEPK 273

  Fly   426 SKTIVSPEGGWTTTSNITAVVEPNKRSLVVICHGLNMQLTENVVSTHTINVLYPPAPPLISGYME 490
            .    |..||:...|:......|..:...:.|...:..|.:.|  |.|:.:              
 Frog   274 K----SESGGFIKESHYRIPSGPGNQLAKITCEAYHETLHQPV--TETLQI-------------- 318

  Fly   491 GQIIPAGSVQKLLCVSSGGNPLATLTWYKNDKRINSVIRAADKS-----VSAEITILANVSDNQA 550
                 |.|.:...|  :|...|..|.          ||....||     ||:..|::::..:...
 Frog   319 -----AKSYRHYYC--TGAAILFILL----------VILCLVKSLQNFPVSSIHTLMSDDGEKVT 366

  Fly   551 QYRCEASNSATEIPLFQSTTLSVHFAPETVK--IRIEPEELR-PGMEATIICDSSSSNPPAKLSW 612
            .| |.||:...|    ...|.:|....||.|  ||...|..| .|...|.:..|..|.  |.|| 
 Frog   367 LY-CVASDCPEE----PRVTWTVTEGSETKKKVIRTGTETRREKGSVPTSLTQSGESE--ALLS- 423

  Fly   613 WKDGIPIEGINNTSKPGLWGGTVSTLEFRVNVTQEMNGQVYTCQSANEALQRSAHEAVSLDVLYR 677
              :| |....::....|...|.:|||.|:.:..:..|.: ::||.......|....:.   :|.|
 Frog   424 --EG-PYTMRSDRLAAGGLHGVLSTLSFKPDAQKHKNIE-FSCQFVCGGKIRERKYSF---ILRR 481

  Fly   678 PKFVPPPSSTAVGVEGESLQVSLQTRANPTPVTYKWTKDGTTIPQDGDHRIFADGGSLNFTRLHR 742
            ||...|...:.:..|.....|:|| ...|.|:..||: .|....||.:.:          |::: 
 Frog   482 PKASGPIQMSIIENEVVLCSVALQ-EFYPKPIQIKWS-CGVGCYQDLESK----------TQIN- 533

  Fly   743 DDAGIYSCSASNSQGGATLNITVVVEYGTTIKSVSENIVVNPGEDAMLSCTVEG---KPLTEEHV 804
               .|.|..|.|::....:....:.:.|..::...|:..:...|...||....|   :|..||.:
 Frog   534 ---PISSTQAFNAESECKIPAQRLKDPGFKVRVTWEHESMTGPEQKELSVRDGGFQWRPFMEEII 595

  Fly   805 K---------------WERVGY---DMTVKTSTTFANGTSYLHIK----------DAKREDVGNF 841
            .               |   ||   .:.||.....|.|...|.:.          :.|||..|.|
 Frog   596 TPTLRHGTEGRFQCKIW---GYFPDALEVKWLRREAGGQELLSVSPSEKYKIPEMEQKREADGTF 657

  Fly   842 RCVA----------DN------RVDNPTNRDILLIVKFAPEIAKTPTLLRAASGTGERGRLPCRA 890
            .|.|          ||      ||.:.:.|:.|.....|..:...| ::|:.:.||  |::....
 Frog   658 SCTAALIVSVSGKSDNETEFICRVGHSSLREPLEKSTGALSVGGAP-VIRSITRTG--GKITAEI 719

  Fly   891 QGSPKPQFI---WRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVA 948
            . ...||.|   |.:.|:    .:..|||         .||:..|..:......|.|..::
 Frog   720 D-QFYPQGITVTWSRTKE----GKDDKYE---------EYEAPRISTEPPTNSDGTYRIIS 766

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352 27/131 (21%)
Ig 76..155 CDD:299845 24/114 (21%)
IG_like 186..279 CDD:214653 19/92 (21%)
Ig 197..279 CDD:299845 18/81 (22%)
IG_like 296..376 CDD:214653 14/80 (18%)
Ig 300..361 CDD:299845 13/61 (21%)
Ig 380..454 CDD:299845 13/73 (18%)
IG_like 490..573 CDD:214653 19/87 (22%)
Ig 501..560 CDD:299845 15/63 (24%)
Ig 584..666 CDD:299845 21/82 (26%)
IG_like 585..666 CDD:214653 21/81 (26%)
I-set 678..767 CDD:254352 19/88 (22%)
IGc2 692..757 CDD:197706 16/64 (25%)
Ig 788..849 CDD:143165 23/107 (21%)
Ig 885..960 CDD:143165 13/67 (19%)
FN3 967..1051 CDD:238020
LOC101734363XP_031749262.1 FR1 25..39 CDD:409353 1/13 (8%)
Ig strand A 25..30 CDD:409353 0/4 (0%)
V-set 31..125 CDD:400157 24/116 (21%)
Ig strand B 33..39 CDD:409353 0/5 (0%)
CDR1 40..52 CDD:409353 3/25 (12%)
FR2 53..60 CDD:409353 0/6 (0%)
Ig strand C 53..59 CDD:409353 0/5 (0%)
CDR2 62..83 CDD:409353 3/20 (15%)
Ig strand C' 64..69 CDD:409353 2/4 (50%)
Ig strand C' 72..74 CDD:409353 0/1 (0%)
FR3 84..113 CDD:409353 10/32 (31%)
Ig strand E 91..97 CDD:409353 0/5 (0%)
Ig strand F 104..112 CDD:409353 3/11 (27%)
CDR3 114..116 CDD:409353 0/1 (0%)
IgC1 140..221 CDD:409354 18/85 (21%)
Ig strand B 144..148 CDD:409354 1/4 (25%)
Ig strand C 159..163 CDD:409354 1/3 (33%)
Ig strand E 189..193 CDD:409354 2/3 (67%)
Ig strand F 203..208 CDD:409354 1/4 (25%)
Ig strand G 218..221 CDD:409354 0/2 (0%)
IgC1 230..316 CDD:409354 29/158 (18%)
Ig strand C 259..263 CDD:409354 2/3 (67%)
Ig strand E 284..288 CDD:409354 1/3 (33%)
Ig strand F 298..303 CDD:409354 1/4 (25%)
Ig strand G 313..316 CDD:409354 1/2 (50%)
IgC1 <609..694 CDD:409354 21/87 (24%)
Ig strand C 620..624 CDD:409354 2/3 (67%)
Ig strand E 661..665 CDD:409354 1/3 (33%)
Ig strand F 676..681 CDD:409354 0/4 (0%)
Ig strand G 691..694 CDD:409354 0/2 (0%)
Ig <722..797 CDD:416386 13/58 (22%)
Ig strand C 726..732 CDD:409353 1/5 (20%)
Ig strand C' 741..744 CDD:409353 3/11 (27%)
Ig strand D 752..755 CDD:409353 0/2 (0%)
Ig strand E 762..769 CDD:409353 1/5 (20%)
Ig strand F 779..786 CDD:409353
Ig strand G 794..797 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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