DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and myom3

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:XP_031752072.1 Gene:myom3 / 101734332 XenbaseID:XB-GENE-490325 Length:1443 Species:Xenopus tropicalis


Alignment Length:1177 Identity:231/1177 - (19%)
Similarity:364/1177 - (30%) Gaps:430/1177 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   521 DKRINSVIRAADKSVSAEITILANVSDNQAQYRCE----------ASNSATEIPLFQSTTLSVHF 575
            :||:.|..:..:.|           ..||.|:..:          :.....:||: .|..||:  
 Frog     2 EKRVTSFNKQEEMS-----------QLNQRQFEMQSRTLKRKFRTSDEELEDIPV-SSIELSI-- 52

  Fly   576 APETVKIRIEPEELRPGMEATIICDSSSSNPPAKLSWWKDGIPIEGINNTSKPGLWGGTVSTLEF 640
                  ||.| :.|:|..|:....||.        ..|.|      .::..:.|          |
 Frog    53 ------IRAE-QTLKPSWESKAQFDSR--------EMWMD------TSDQKREG----------F 86

  Fly   641 RVNVTQEMN-GQVYTCQSANE-----ALQRSAHEAVSLDVLYR-------PKFVPPPSSTAVGVE 692
            | |..:::. |.:..|::..|     :|:|.|.|.......:|       |.|..|..:..|. |
 Frog    87 R-NYMEKLEIGVIQACRALRERSDCKSLRRKAEEKARQQKEFRELCARRAPMFWVPLRAHCVW-E 149

  Fly   693 GESLQVSLQTRANPTPVTYKWTKDGTTIPQD------GDHRIFADGG--SLNFTRLHRDDAGIYS 749
            ..|:.::.....||.| |.:|.|:|  :|.|      |.:||..:.|  :|...|...:|:..||
 Frog   150 RMSVNLTCTIMGNPKP-TVQWIKNG--VPIDLRSSPPGKYRILDEYGMLTLEIRRCTLEDSADYS 211

  Fly   750 CSASNSQGGATLNITVVVE------YGTTI---------------------------KSVSENIV 781
            ...:|..|.||....|:|:      |.|.:                           .|:.:.:.
 Frog   212 VVVTNDFGQATSFANVLVKSKMNKFYFTNVFTEYQGLKSGWDSVSYPSLLPVYEGEFTSLLKPVF 276

  Fly   782 VNPGEDAMLSCTVEGKPLTEEHV---KWERVG--------------------------------Y 811
            ....|..::||.|...  .|.||   :|.|.|                                |
 Frog   277 TREKEPFIMSCVVSSN--IERHVQSIQWYRDGLLLKESQRRKMAINGCDLSLNVAPAFKEDEGLY 339

  Fly   812 DMTVKTSTTFANGTSYLHIKDAKREDVG------NFRCVADNRVDNPTNRDILLIVKFAPEIAKT 870
            .:.:.:|:.....::|:.::|||.|..|      ..||.       ..|||.::       :|.|
 Frog   340 TVQIPSSSGHQEQSAYVFVRDAKPEKYGVPGAPLCVRCY-------DINRDSVM-------LAWT 390

  Fly   871 PTLLRAASGTGERGR-----------------LPCRAQGSPKPQFIWRQDKKDLPINRTYKYEVE 918
            |.       :.:||.                 .||    :..|..|.|.....|....||::.| 
 Frog   391 PP-------SDDRGSHVIGYYVEKCDISIHQWTPC----NEVPTKICRLPVSGLTEGNTYQFRV- 443

  Fly   919 ERKID----SLTYESTLIVDKVAPADYG-----AYE-----CVARNELGEAVETVRLEITSQPDP 969
             |.::    ||..:::..|..:.||:..     .|:     .|:|::|.|:|:        .|.|
 Frog   444 -RAVNQAGISLPSKASQPVTMMDPAEKDRLIVIPYDEQRAITVSRDDLQESVK--------MPLP 499

  Fly   970 PLSLNILNVTHDTVTLAW-TPGFDGGLKASYRVRYRMADREQYKYI--DGLPNSHKLTIGGLRMN 1031
            |.:::...:..|.:.|.| .|...|.....|.|...::....::.|  :...||.:.::..|..|
 Frog   500 PTNVHASEIHEDYIVLCWDEPDPHGKESLFYYVEQAISGTNNWQRIMLETTLNSPRCSLFHLDKN 564

  Fly  1032 TLYLFSVMSWNELGQSSYLPDLARAETKEAPPPSHPASSLGGGPPTTSQTPLGGTSGMLLVGVGA 1096
            ..|.|.|.|.|:.|.||               ||.|:..:  .|..|...|......:.......
 Frog   565 KSYCFRVRSANKFGVSS---------------PSDPSEPI--SPKATLAIPPAPGHIIAFRDTNK 612

  Fly  1097 GIVV----VLLNVFVIGCCLHKR----------NEKRLKRGLELMP-----------------AE 1130
            ..||    |..:..::|..|:.|          |.|.||.....:|                 |.
 Frog   613 SAVVQWQMVEDDPDILGYYLYSRLSGEEEWQTVNNKPLKGTRFTVPELQTGKQYEFCVRAVNEAG 677

  Fly  1131 LTEDSSNTPNLVI---IGISLAAFGFLLV----NASLVAW-------------FFVHQRRKKVA- 1174
            |:|.|..:..:.|   |....|.:||.|:    :...::|             :|:.|...... 
 Frog   678 LSERSPPSEPITISEAIYCPTAPYGFALLCCGKDEMTISWKAPKFTAGREVLGYFLDQHDSLEVT 742

  Fly  1175 --ETTNQPAKTATIEM----------YAPSSYNDTVTGETLSSVSEKSESYSNEGSSQPEYIDEV 1227
              |..:||......::          :...:.|.:..|:    :||.|:.:..|..:.||     
 Frog   743 WQEVNSQPIPKRLCKVPDLTEGHFYEFRAKALNSSGVGK----MSEPSDLFKCEEWTMPE----- 798

  Fly  1228 RKKAASTYLVEGSDMPPPRYQKDGT------------LPVIYPNNVVNACTLPHPRHNNG----S 1276
                           |.|.|....|            .|:......|....:....|.:|    .
 Frog   799 ---------------PGPPYDVRSTEVRNTSLMLQWEAPIYTGIGPVTGYIIEIREHGSGLDWKR 848

  Fly  1277 AAIHMTRDDQMLISK------------GVYIPSPS----PAPP------PDGSYYNMNSDRY-LS 1318
            ...::..|..|.||.            ||....|.    |..|      |..:...:..|.. |.
 Frog   849 INENIVADTHMRISDLETGKCYELRVLGVNAAGPGLPSLPCDPVVAETKPGTNEIEVGVDEEGLI 913

  Fly  1319 YPPMEYPAALDFTAQPMPMAHLQPMTVTSLATNGGPTL-------IGNGSVAAVAGGS----GTL 1372
            |...|.|..:|           .|..:.|....|.|.|       .||.|...:...|    ||.
 Frog   914 YLAFENPEPID-----------SPQFIWSKDYKGAPDLERTEISTDGNRSKLVLTNPSEKDLGTY 967

  Fly  1373 RRGILRGVVGVPQPDVTHHTSTVGGSPMQMLHDLHPVNLSASTLTTSTTLNGSLPTATATLPRQP 1437
                   .|.||..|                      .:|||.:.|...|        |.|.|:.
 Frog   968 -------AVEVPNTD----------------------GISASHILTEKEL--------ADLLRRS 995

  Fly  1438 HGILKDP 1444
            |.| |.|
 Frog   996 HDI-KHP 1001

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653
Ig 197..279 CDD:299845
IG_like 296..376 CDD:214653
Ig 300..361 CDD:299845
Ig 380..454 CDD:299845
IG_like 490..573 CDD:214653 11/61 (18%)
Ig 501..560 CDD:299845 7/48 (15%)
Ig 584..666 CDD:299845 17/87 (20%)
IG_like 585..666 CDD:214653 17/86 (20%)
I-set 678..767 CDD:254352 29/96 (30%)
IGc2 692..757 CDD:197706 21/72 (29%)
Ig 788..849 CDD:143165 19/101 (19%)
Ig 885..960 CDD:143165 21/105 (20%)
FN3 967..1051 CDD:238020 23/86 (27%)
myom3XP_031752072.1 Ig strand D 315..320 CDD:409353 0/4 (0%)
Ig strand E 323..328 CDD:409353 0/4 (0%)
Ig strand F 337..345 CDD:409353 1/7 (14%)
Ig strand G 348..358 CDD:409353 1/9 (11%)
FN3 369..462 CDD:238020 22/119 (18%)
FN3 497..589 CDD:238020 26/106 (25%)
FN3 598..689 CDD:238020 16/90 (18%)
FN3 697..786 CDD:238020 14/92 (15%)
FN3 799..896 CDD:238020 17/96 (18%)
Ig 926..983 CDD:409353 18/85 (21%)
Ig strand C 927..931 CDD:409353 0/3 (0%)
Ig strand E 952..956 CDD:409353 1/3 (33%)
Ig strand F 966..971 CDD:409353 2/11 (18%)
Ig strand G 980..983 CDD:409353 1/2 (50%)
Ig 1117..1201 CDD:416386
Ig strand A 1117..1120 CDD:409353
Ig strand A' 1123..1127 CDD:409353
Ig strand B 1132..1139 CDD:409353
Ig strand C 1147..1153 CDD:409353
Ig strand C' 1154..1157 CDD:409353
Ig strand D 1159..1165 CDD:409353
Ig strand E 1168..1178 CDD:409353
Ig strand F 1182..1190 CDD:409353
Ig strand G 1192..1201 CDD:409353
Ig 1330..1420 CDD:416386
Ig strand A 1330..1333 CDD:409353
Ig strand A' 1338..1343 CDD:409353
BAR <15..>120 CDD:416402 29/150 (19%)
Ig 136..230 CDD:416386 29/97 (30%)
Ig strand A 136..138 CDD:409353 1/1 (100%)
Ig strand A' 140..146 CDD:409353 1/5 (20%)
Ig strand B 153..160 CDD:409353 0/6 (0%)
Ig strand C 166..171 CDD:409353 2/4 (50%)
Ig strand C' 173..176 CDD:409353 1/4 (25%)
Ig strand D 185..189 CDD:409353 1/3 (33%)
Ig strand E 194..201 CDD:409353 1/6 (17%)
Ig strand F 208..216 CDD:409353 2/7 (29%)
Ig strand G 219..230 CDD:409353 4/10 (40%)
Ig 267..358 CDD:416386 14/92 (15%)
Ig strand A' 271..275 CDD:409353 0/3 (0%)
Ig strand B 283..291 CDD:409353 3/7 (43%)
Ig strand C 299..304 CDD:409353 1/4 (25%)
Ig strand C' 307..309 CDD:409353 0/1 (0%)
Ig strand B 1347..1354 CDD:409353
Ig strand C 1361..1366 CDD:409353
Ig strand C' 1369..1371 CDD:409353
Ig strand D 1376..1382 CDD:409353
Ig strand E 1385..1390 CDD:409353
Ig strand F 1400..1407 CDD:409353
Ig strand G 1410..1420 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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