DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and hepacam

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_002937565.2	Gene:	hepacam / 100493229	XenbaseID:	XB-GENE-6051119	Length:	415	Species:	Xenopus tropicalis

Alignment Length:	398	Identity:	88/398 - (22%)
Similarity:	147/398 - (36%)	Gaps:	92/398 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   727 RIFADGGSLNFTRLHRDDAGIYSCSASNSQGGATLNITVVVE--YGTTIKSVSENIVVNPGEDAM 789
            |:|:....|:.|.|.....|:..          .:|||..|:  :||.            |:.|:
Frog    10 RVFSSLAVLHVTYLLAIQTGVVE----------VVNITSHVQHIHGTV------------GKSAL 52

  Fly   790 LS----CTVEGKPLTEEHVKWER-------VGYDMTVKTST-------TFANGTSYLHIKDAKRE 836
            ||    .:...||:.:..||.|:       :|.::.....|       .|.||:  |.||:....
Frog    53 LSVQYTSSSSDKPVVKWQVKREKPVTVVQSIGTEIIGNLRTDYKDRIQIFENGS--LLIKNLMLS 115

  Fly   837 DVGNFRCVADNRVDNPTNRDILLIVKFAPEIAKTPTLLRAASGT---GERGRLPCRAQGSPKPQF 898
            |.|.:........|..|....:.:....| |:| |.::.|:|..   .|...|.|..:...|..:
Frog   116 DEGTYEVEVSITDDTFTGEKSINLTVDVP-ISK-PQVIVASSTVLELTENFTLNCFHENGTKTSY 178

  Fly   899 IWRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARNEL--GEAVETVRL 961
            .|.::.| |.||       :.|.|.|..:: .|.:.::..:|...|.|:..|.:  |.:| .::|
Frog   179 TWLKNGK-LLIN-------DSRIIFSPDHK-VLTITRIIMSDDDIYSCMVENSISNGRSV-PIKL 233

  Fly   962 EITSQPDPPLSLN----ILNVTHDTVTLAWTPGFDGGLKASYRVRYRMADREQYKYID--GLPNS 1020
            .:..:....:.|:    .|.||..||...|.|        |.:.:.:.......:|:|  |.|..
Frog   234 TVYRRSSLYIILSTGGIFLLVTLVTVCACWKP--------SRKKKQKYEKHGSSEYLDRIGEPLK 290

  Fly  1021 HKLTIGGLR-----MNTLYLFSVMSWNELGQSSYLPDLARAETKEAPPPSHPASSLGGGPPTTSQ 1080
            :::.|....     .|.:.|:            .|.|....|.:|..|.....:|..|.|...|.
Frog   291 NEVEIISRSGEPECKNPVALY------------ILKDKESVEAEEDSPTESRTASDHGSPSYVST 343

  Fly  1081 TPLGGTSG 1088
            :|.|.:||
Frog   344 SPSGRSSG 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352	9/39 (23%)
		IGc2	692..757	CDD:197706	6/29 (21%)
		Ig	788..849	CDD:143165	18/78 (23%)
		Ig	885..960	CDD:143165	18/76 (24%)
		FN3	967..1051	CDD:238020	16/94 (17%)
hepacam	XP_002937565.2	V-set	43..141	CDD:369466	23/111 (21%)
hepacam	XP_002937565.2	Ig_3	148..221	CDD:372822	19/81 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910