DRSC/TRiP Functional Genomics Resources

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Protein Alignment sns and Kirrel2

DIOPT Version :9

Sequence 1:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster
Sequence 2:XP_038957463.1 Gene:Kirrel2 / 100359836 RGDID:1308456 Length:711 Species:Rattus norvegicus


Alignment Length:757 Identity:186/757 - (24%)
Similarity:281/757 - (37%) Gaps:159/757 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 WIKH--LQLLRLLAVIVLASAPVPSHAQQQKFRTTPHDLQVLEGAEAMMRCEVANVAGAVQWTKD 107
            |:.|  :..|.....::|.|:|   |..||     |.|:.||.|.||.:.|.:....|.||||||
  Rat    11 WVLHKGIPFLSSAIPLLLGSSP---HFLQQ-----PEDMVVLLGQEARLPCALGAYRGLVQWTKD 67

  Fly   108 GFALGFSAVIPGFPRYSVLGDRKQGIYNLRISNASINDDADYQCQVGPARLNSAIRANAKLTVIS 172
            |.|||....:||:.||.:.|:...|.::|.|....:.|:|.|:||...|.|.|   ..|:|.|:.
  Rat    68 GLALGGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQASQAGLRS---RPAQLHVMV 129

  Fly   173 PPASIEIKGYSHNSKVEVRENQDLQLKC-IVANAKPAAQIVWYRGNVEYK---------PEKRED 227
            ||.:.::.|   ...|.:.......|.| ...:|:||.:::|:|..:...         .:|...
  Rat   130 PPEAPQVLG---GPSVSLVAGVPGNLTCRSRGDARPAPELLWFRDGIRLDGTSFHQITLRDKATG 191

  Fly   228 TVEESTAKRFTTTSSLKLKPGPDDDYTEYTCQARHKALSPDMPMRATVQLSVLYPPGPPYIEGYS 292
            |||          ::|.|.|...||.....|:||.:||.....  ..|.||:.|   ||.:...:
  Rat   192 TVE----------NTLFLTPSSQDDGATLICRARSQALPTGRD--TAVTLSLQY---PPMVTLSA 241

  Fly   293 AGETLRRGQTVELMCRSRGGNPPAQLIWYKNGSQIRMAYRTSGRLSENI--YTFTAEAGDNKARF 355
            ..:|.:.|:.|..:|::....|.....|.|.||.:..|   .|...|.:  .||..|.      .
  Rat   242 EPQTAQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGA---RGPRLEVVADATFLTEP------V 297

  Fly   356 RCEASN-VMSQNPLKAEVELSVLFAPTHVTVMGPTEARVGDIVPLTCTTAPSNPPAEIKW-MVGG 418
            .||.|| |.|.|...|   |.||:.|.......|....||.....:|... .||...|.| .:||
  Rat   298 SCEVSNAVGSANRSTA---LEVLYGPILQAKPKPVSVDVGKDASFSCVWR-GNPLPRISWTRLGG 358

  Fly   419 RQVRNATSKTIVSPEGGWTTTSNITAVVEPNKRSLVVICHGLNMQLTENVVSTHTINVLYPPAPP 483
            .||. ::..|:..|........:.....||.:..:    .|...|....|.:...:..|: |||.
  Rat   359 SQVL-SSGPTLRLPSVALEDAGDYVCRAEPRRTGV----GGGTAQARLTVNAPPVVTALH-PAPA 417

  Fly   484 LISGYMEGQIIPAGSVQKLLCV--SSGGNPLATLTWYKNDKRINSVIRAADKSVSAE-------- 538
            .:.|       ||    :|.||  :|........:|.:......|:.|...::..|.        
  Rat   418 FLRG-------PA----RLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGP 471

  Fly   539 --ITIL----ANVSDNQAQYRCEASNSATEIPLFQSTTLSVHFAPETVKIRIEPEELRPGMEATI 597
              |::|    ...||....:.|.|.|...|               ..|:|.:...:|.|.:....
  Rat   472 GLISVLHISGTQESDFTTGFNCSARNRLGE---------------GRVQIHLGRRDLLPTVRLVA 521

  Fly   598 ICDSSSSN-----PPAKLSWWKDGIPIEGINNTSKPG-LWGGTVSTLEFRVNVTQEMNGQVYTCQ 656
            ...|::::     ....|..|:.|...:..|....|| ..|.:....|.....:::....|:|..
  Rat   522 GAASAATSLFMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSAHGPEEETGSSEDRGPIVHTDH 586

  Fly   657 S-----ANEALQ---------RSAHEAVSLDVLYRP---KFVPPPSSTAVGVEGESLQVSLQTRA 704
            :     .||||:         :....:|||.:...|   .|:||||  .:|:.|           
  Rat   587 NDLVLEENEALETKDPTNGYYKVRGVSVSLSLGEAPGGGLFLPPPS--PMGLPG----------- 638

  Fly   705 NPTPVTYKWTKDGTTIPQDGDHRIFADGGSLNFTRLHRDDAG 746
              ||..|.:......:|.               .||:|..||
  Rat   639 --TPTYYDFKPHLDLVPP---------------CRLYRARAG 663

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snsNP_001036532.1 I-set 73..170 CDD:254352 37/96 (39%)
Ig 76..155 CDD:299845 32/78 (41%)
IG_like 186..279 CDD:214653 24/102 (24%)
Ig 197..279 CDD:299845 23/91 (25%)
IG_like 296..376 CDD:214653 24/82 (29%)
Ig 300..361 CDD:299845 16/62 (26%)
Ig 380..454 CDD:299845 17/74 (23%)
IG_like 490..573 CDD:214653 18/98 (18%)
Ig 501..560 CDD:299845 15/74 (20%)
Ig 584..666 CDD:299845 17/101 (17%)
IG_like 585..666 CDD:214653 17/100 (17%)
I-set 678..767 CDD:254352 17/72 (24%)
IGc2 692..757 CDD:197706 10/55 (18%)
Ig 788..849 CDD:143165
Ig 885..960 CDD:143165
FN3 967..1051 CDD:238020
Kirrel2XP_038957463.1 IG_like 38..127 CDD:214653 37/91 (41%)
Ig strand A' 40..44 CDD:409353 1/3 (33%)
Ig strand B 48..57 CDD:409353 3/8 (38%)
Ig strand C 62..66 CDD:409353 3/3 (100%)
Ig strand D 75..85 CDD:409353 4/9 (44%)
Ig strand E 88..100 CDD:409353 3/11 (27%)
Ig strand F 107..115 CDD:409353 4/7 (57%)
Ig strand G 117..127 CDD:409353 4/12 (33%)
Ig 133..231 CDD:416386 25/112 (22%)
Ig strand A 134..137 CDD:409353 0/2 (0%)
Ig strand A' 140..144 CDD:409353 1/3 (33%)
Ig strand B 151..158 CDD:409353 2/6 (33%)
Ig strand C 164..169 CDD:409353 0/4 (0%)
Ig strand C' 172..174 CDD:409353 0/1 (0%)
Ig strand D 177..184 CDD:409353 0/6 (0%)
Ig strand E 191..199 CDD:409353 4/17 (24%)
Ig strand F 208..216 CDD:409353 2/7 (29%)
Ig strand G 222..228 CDD:409353 0/7 (0%)
Ig_3 234..303 CDD:404760 19/77 (25%)
Ig strand B 252..256 CDD:409353 1/3 (33%)
Ig strand C 266..270 CDD:409353 0/3 (0%)
Ig strand E 283..286 CDD:409353 0/2 (0%)
Ig strand F 292..301 CDD:409353 3/14 (21%)
Ig strand G 309..312 CDD:409353 1/2 (50%)
Ig 326..403 CDD:416386 18/82 (22%)
Ig strand A' 327..332 CDD:409353 1/4 (25%)
Ig strand B 335..344 CDD:409353 1/8 (13%)
Ig strand C 350..354 CDD:409353 1/3 (33%)
Ig strand C' 357..359 CDD:409353 1/1 (100%)
Ig strand D 362..365 CDD:409353 0/3 (0%)
Ig strand E 366..371 CDD:409353 1/4 (25%)
Ig strand F 379..387 CDD:409353 0/7 (0%)
Ig strand G 393..403 CDD:409353 2/9 (22%)
Ig 405..509 CDD:416386 25/130 (19%)
Ig strand A 406..410 CDD:409353 0/3 (0%)
Ig strand A' 412..415 CDD:409353 1/3 (33%)
Ig strand B 423..430 CDD:409353 4/10 (40%)
Ig strand C 437..442 CDD:409353 0/4 (0%)
Ig strand C' 444..447 CDD:409353 0/2 (0%)
Ig strand D 455..462 CDD:409353 0/6 (0%)
Ig strand E 472..479 CDD:409353 2/6 (33%)
Ig strand F 490..497 CDD:409353 2/6 (33%)
Ig strand G 500..507 CDD:409353 2/21 (10%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D141865at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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