DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and si:ch211-141e20.2

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_009302934.1	Gene:	si:ch211-141e20.2 / 100150732	ZFINID:	ZDB-GENE-070912-75	Length:	424	Species:	Danio rerio

Alignment Length:	291	Identity:	77/291 - (26%)
Similarity:	116/291 - (39%)	Gaps:	93/291 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   322 KNGS-QIR-MAYRTSGRLSENIYTFTAEAGDNKARFRCEASNVMSQNPLKAEVELSVLFAPTHVT 384
            :||| |:| |.:     |.|..||             | ..|:....|:...::.|| ||...||
Zfish   114 RNGSIQLRGMEF-----LDEGTYT-------------C-IFNLFPSGPIATYIKASV-FARPAVT 158

  Fly   385 VMGPTEARVG--DIVPLTCTTAPSNPPAEIKWMVG--GRQVRNATSKTIVSPEGGWTTT------ 439
            |.| .|..:|  :::..:|..:.:.|.||:.|.:|  .:.::..|:.|:.:.|   |.|
Zfish   159 VKG-EEPVIGCLEVILASCFASNARPAAEVTWRLGELEKSLKTRTNHTVNANE---TITVVSYLL 219

  Fly   440 ---------SNITAVVEPNKRSLVVICHGLNMQLTENVVSTHTINVLYPPAPPLISGYMEGQIIP 495
                     .||..||:.|             .|||::|..:||::.|||...:        |||
Zfish   220 GVPFKHLHKKNIQCVVKHN-------------SLTEHLVLNYTIDIHYPPESVI--------IIP 263

  Fly   496 AGS--VQKLLCVSSGGNPLATLTWYKNDKRINSVI------RAADKSVSAEITILANVSDNQAQY 552
            ..|  |.:..|:.. .||..||..| |..|:|...      |....:::.|:..|         |
Zfish   264 DSSTDVNEFRCIVD-SNPQPTLKGY-NWTRVNKSSQFFEGNRLPVPNMTPELNGL---------Y 317

  Fly   553 RCEASN---SATEIPLFQSTTLSVHFAPETV 580
            .|.|||   ||     ..|..::||..|.:|
Zfish   318 ICNASNKYGSA-----LGSLYVNVHAEPSSV 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653	13/55 (24%)
		Ig	300..361	CDD:299845	11/40 (28%)
		Ig	380..454	CDD:299845	22/92 (24%)
		IG_like	490..573	CDD:214653	25/93 (27%)
		Ig	501..560	CDD:299845	17/67 (25%)
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
si:ch211-141e20.2	XP_009302934.1	Ig	52..143	CDD:325142	12/47 (26%)
		Ig	163..250	CDD:325142	22/102 (22%)
		Ig	271..336	CDD:325142	20/80 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910