DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and si:ch211-222f23.6

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	NP_001120876.1	Gene:	si:ch211-222f23.6 / 100141493	ZFINID:	ZDB-GENE-070912-208	Length:	367	Species:	Danio rerio

Alignment Length:	318	Identity:	71/318 - (22%)
Similarity:	110/318 - (34%)	Gaps:	65/318 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 RTTPHDLQVLEGAEAMMRCEVANV---AGAVQWTK--------DGFALGFSAVIPGFPRYSVLGD 128
            :.:.|:..|:.|.:|.:.|::...   ...|.|.|        :.|   |.....|...:..|.|
Zfish    26 KNSVHNKAVMIGEDATLFCDLTATQENTSRVVWQKQTSENHQPETF---FIIHKDGRTEHRDLQD 87

  Fly   129 RKQGIYNLRISNASIN-------DDADYQC--QVGPARLNSAIRANAKLTVISPPASIEIKGYSH 184
            ..:.:.||..:|.||.       ||..|.|  .:...:....|    .:||:.||.. .:.|.:|
Zfish    88 HVRFVGNLMENNGSIQLMGLKLVDDGIYTCIFTINEQQAQKVI----SVTVLVPPVG-SVMGSTH 147

  Fly   185 NSKVEVRENQDLQLKCIVANAKPAAQIVWYRGNVEYKPEKREDTVEESTAKRFTTTSSLKLKPGP 249
               |....:.|| ..|:.:.|:|||::.|..|.:.........:.|.|.. .||..|.:...|..
Zfish   148 ---VSGAFSVDL-ASCMASGARPAARVFWRLGALNTSLNTHTSSTEHSDG-TFTVQSHIYGVPSK 207

  Fly   250 DDDYTEYTCQARHKALSPDMPMRATVQLSVLYPP-----------GPPYIEGYSAGETLRRGQTV 303
            .....:..|..:|...:.|:.:.  .|::|.|||           .|...|.|..
Zfish   208 HLHQKKIQCVVQHITFTEDLELE--YQINVHYPPDLVIISPDDPNNPAEAEEYHC---------- 260

  Fly   304 ELMCRSRGGNPPAQLIWYKNGSQIRMAYRTSGRLSENIYTFTAEAGDNKARFRCEASN 361
            |:.|     ||....||.:.......|.|..|    |.......:.|....:.|.|||
Zfish   261 EVDC-----NPTPTYIWKRMNESEGRAPRYEG----NKLFLPKSSVDLNGVYICTASN 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352	23/114 (20%)
		Ig	76..155	CDD:299845	22/98 (22%)
		IG_like	186..279	CDD:214653	20/92 (22%)
		Ig	197..279	CDD:299845	17/81 (21%)
		IG_like	296..376	CDD:214653	15/66 (23%)
		Ig	300..361	CDD:299845	13/60 (22%)
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
si:ch211-222f23.6	NP_001120876.1	V-set	34..135	CDD:284989	23/107 (21%)
		IG_like	34..134	CDD:214653	22/106 (21%)
		Ig	138..235	CDD:299845	23/104 (22%)
		Ig	257..317	CDD:299845	16/72 (22%)
		IG_like	259..321	CDD:214653	15/70 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910