DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and jam2b

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	NP_001121766.1	Gene:	jam2b / 100005301	ZFINID:	ZDB-GENE-080229-3	Length:	306	Species:	Danio rerio

Alignment Length:	294	Identity:	74/294 - (25%)
Similarity:	116/294 - (39%)	Gaps:	66/294 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   577 PETVKIRIEPEELRPGMEATIICD---SSSSNPPAKLSWWKDG-----IPIEGINNTSKPGLWGG 633
            |.||.......::.....|.:.|:   ...:||  ::.|.|.|     :..||....|..|....
Zfish    32 PVTVTTSKAKMDVHENTNAVLSCEFRTEKETNP--RVEWKKRGKDVSYVYFEGDFTGSYKGRASI 94

  Fly   634 TVSTLEFRVNVTQEMNGQVYTCQ-SANEALQRSAHEAVSLDVLYRPKFVPPPSST-----AVGVE 692
            ..:||..| .|||:.:| ||.|: :|.:...:....:|:|.||     |||.:.|     || :.
Zfish    95 DGATLTLR-GVTQKDSG-VYHCEVTARQDKIKLGEVSVTLSVL-----VPPHAPTCEVPEAV-MR 151

  Fly   693 GESLQVSLQTRANPTPVTYKWTKD----GTTIPQDGDHRIFADGGSLNFTRLHRDDAGIYSCSAS 753
            |.|.::..:.:.:....||.|.||    .|..|.|..:.:....|||.|..:.:.|.|.|.|.||
Zfish   152 GFSAELHCKDKLSVPAATYSWYKDNKPLNTANPHDVHYTLDTKTGSLKFKSVSKSDEGQYRCEAS 216

  Fly   754 NSQGGA-------------TLNITVV--VEYGTTIKSVSENIVVNPGEDAMLSCTVEG-----KP 798
            |..|..             .||:|::  :|.|..:..||..:       ::..|...|     :.
Zfish   217 NGVGAPKSCAGHHMKITEFELNMTMIIAIEVGAFLLLVSCCV-------SICLCCRRGCCHCCRR 274

  Fly   799 LTEEHVKWERVGYDMTVKTSTTFANGTS---YLH 829
            .::|.:|..        ||.|::...|.   |.|
Zfish   275 QSKEEIKQS--------KTKTSYNQPTDPRRYKH 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845	22/90 (24%)
		IG_like	585..666	CDD:214653	22/89 (25%)
		I-set	678..767	CDD:254352	31/112 (28%)
		IGc2	692..757	CDD:197706	21/68 (31%)
		Ig	788..849	CDD:143165	10/50 (20%)
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
jam2b	NP_001121766.1	Ig	44..135	CDD:299845	24/94 (26%)
		IG_like	44..134	CDD:214653	24/93 (26%)
		IGc2	154..220	CDD:197706	20/65 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910