DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and si:ch211-286b5.8

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_017212152.1	Gene:	si:ch211-286b5.8 / 100003760	ZFINID:	ZDB-GENE-121214-73	Length:	357	Species:	Danio rerio

Alignment Length:	210	Identity:	54/210 - (25%)
Similarity:	99/210 - (47%)	Gaps:	29/210 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   582 IRIE-PEELRPGMEATIICDSSSSNPPAKLSWWKDGIPIEGINNTSKPGLWGGTVSTLEFRVNVT 645
            :|:| |.|:..|....:.|.||.:...:..||:::|   |..:.:.:.       :.|..: :|:
Zfish    92 LRVETPAEVVEGDSPVLTCKSSCNLGSSIFSWYRNG---ESFSESVRQ-------NQLILQ-SVS 145

  Fly   646 QEMNGQVYTCQSANEALQRSAHEAVSLDVLYRPKFVP-PPSSTAVGVEGESLQVSLQTRANPTPV 709
            :|.:|. |:|  |...|:.....|::|:|.|.||.|. ..|.:||.|.|:|:.:|..:.:||..:
Zfish   146 REDSGN-YSC--AVRDLKNLPSPALTLNVRYPPKSVSVSVSGSAVIVSGDSVTLSCSSDSNPPAL 207

  Fly   710 TYKWTKDGTTIPQDGDHRIFADGGSLNFTRLHRDDAGIYSCSASNSQGG-ATLNITVVVEYGTTI 773
            .:.|.|:..::       ....|.|.:.:..:...:|.|.|.|.|..|. .:.:|:|.||
Zfish   208 NFTWFKENQSL-------AVGSGQSFSISSFNSSHSGRYYCKAHNKYGSQRSESISVTVE----- 260

  Fly   774 KSVSENIVVNPGEDA 788
            :|.|..:::..|..|
Zfish   261 ESSSSWVLITAGVTA 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845
		IG_like	490..573	CDD:214653
		Ig	501..560	CDD:299845
		Ig	584..666	CDD:299845	19/82 (23%)
		IG_like	585..666	CDD:214653	19/81 (23%)
		I-set	678..767	CDD:254352	24/90 (27%)
		IGc2	692..757	CDD:197706	14/64 (22%)
		Ig	788..849	CDD:143165	1/1 (100%)
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
si:ch211-286b5.8	XP_017212152.1	IG_like	<36..89	CDD:214653
		ig	94..158	CDD:278476	18/77 (23%)
		IG_like	99..171	CDD:214653	19/85 (22%)
		Ig_2	191..255	CDD:290606	15/70 (21%)
		IG_like	191..253	CDD:214653	15/68 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910