DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sns and mhc1lca

DIOPT Version :9

Sequence 1:	NP_001036532.1	Gene:	sns / 44097	FlyBaseID:	FBgn0024189	Length:	1542	Species:	Drosophila melanogaster
Sequence 2:	XP_021329207.1	Gene:	mhc1lca / 100000140	ZFINID:	ZDB-GENE-140820-4	Length:	356	Species:	Danio rerio

Alignment Length:	173	Identity:	38/173 - (21%)
Similarity:	60/173 - (34%)	Gaps:	39/173 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 LKAEVELSVLFAPTHVTVMGPTEARVGDIVPLTC------------TTAPSNPPAEIKWMVGGRQ 420
            ||.|.:..:......|.|:..|.::.|.| .:||            |......|...:.::||..
Zfish   193 LKKEKKRVMARVKPRVRVIQRTCSKTGKI-QMTCLATGFYPRHINLTLLQDGQPVNEERVMGGEL 256

  Fly   421 VRNATSKTIVSPEGGWTTTSNITAVVEPNKRSLVVICHGLNMQLTENV-VSTHTINVLYPPAPPL 484
            :.||        :|.:....::....|..:......|...::.|...: :|      :.|...|:
Zfish   257 LPNA--------DGTYQMRKSVELSAEEQRERRTYTCTVNHLSLDNKLDIS------IEPGLDPV 307

  Fly   485 ISGYMEGQIIPAGSVQKLLCVSSGGNPLATLTWYKNDKRINSV 527
            |       |.|  ||..||||.  |.....|.|.|..|:...|
Zfish   308 I-------IFP--SVLLLLCVF--GVLAGFLMWRKKYKQPEQV 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sns	NP_001036532.1	I-set	73..170	CDD:254352
		Ig	76..155	CDD:299845
		IG_like	186..279	CDD:214653
		Ig	197..279	CDD:299845
		IG_like	296..376	CDD:214653	3/7 (43%)
		Ig	300..361	CDD:299845
		Ig	380..454	CDD:299845	15/85 (18%)
		IG_like	490..573	CDD:214653	14/38 (37%)
		Ig	501..560	CDD:299845	10/27 (37%)
		Ig	584..666	CDD:299845
		IG_like	585..666	CDD:214653
		I-set	678..767	CDD:254352
		IGc2	692..757	CDD:197706
		Ig	788..849	CDD:143165
		Ig	885..960	CDD:143165
		FN3	967..1051	CDD:238020
mhc1lca	XP_021329207.1	IgC_MHC_I_alpha3	204..301	CDD:143322	18/111 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910