DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wit and XIP1

DIOPT Version :9

Sequence 1:	NP_001261395.1	Gene:	wit / 44096	FlyBaseID:	FBgn0024179	Length:	913	Species:	Drosophila melanogaster
Sequence 2:	NP_199777.1	Gene:	XIP1 / 835028	AraportID:	AT5G49660	Length:	966	Species:	Arabidopsis thaliana

Alignment Length:	392	Identity:	84/392 - (21%)
Similarity:	144/392 - (36%)	Gaps:	120/392 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 VVKQGCWKDNTDRTSICSQSECTSSAPTSKTSSLYYCCCSGGVCNAQYSVVEPAPLELGSNEGRT 153
            :::.|..:..:|..::|       ..||:.:|.|.:..|.           ||
plant   551 LIRGGLVESFSDNPNLC-------IPPTAGSSDLKFPMCQ-----------EP------------ 585

  Fly   154 SITNRATEKQHQSFLASTMLGLAGGLTALTIGIFLAVQYCRTAKEKP--EPEESPLAPSGPGYSS 216
                      |.....|::..:...:..|.:|:.:.....|.:|.:.  |.:|: ||.|...|..
plant   586 ----------HGKKKLSSIWAILVSVFILVLGVIMFYLRQRMSKNRAVIEQDET-LASSFFSYDV 639

  Fly   217 N------------LRNVDNMNLIGMLGSGKYGTVMKGLLHDQE-VAVKIYPEEHHQYYVNERNIY 268
            .            |.::.:.|::|..||   |||.:..|...| ||||....:.::...:|..::
plant   640 KSFHRISFDQREILESLVDKNIVGHGGS---GTVYRVELKSGEVVAVKKLWSQSNKDSASEDKMH 701

  Fly   269 -------------ALPLMECPALLSYFGYDERCTMDGRMEYQLVLSLAPLGCLQD---------- 310
                         ::.......|.|||...: |::       ||....|.|.|.|
plant   702 LNKELKTEVETLGSIRHKNIVKLFSYFSSLD-CSL-------LVYEYMPNGNLWDALHKGFVHLE 758

  Fly   311 WLIANTLTFSECCGMLRSITRGISHLHTELRLGDQHKPCVAHRDINTRNVLVQADLSCCIADFGF 375
            |...:.:..        .:.:|:::||.:|      .|.:.||||.:.|:|:..:....:||||.
plant   759 WRTRHQIAV--------GVAQGLAYLHHDL------SPPIIHRDIKSTNILLDVNYQPKVADFGI 809

  Fly   376 ALKVFGSKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAVNLRDCETSLKQMDVYALGLVLWEV 440
            | ||..::.:......||        ||..|:|||....:.....|       |||:.|:||.|:
plant   810 A-KVLQARGKDSTTTVMA--------GTYGYLAPEYAYSSKATIKC-------DVYSFGVVLMEL 858

  Fly   441 AT 442
            .|
plant   859 IT 860

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wit	NP_001261395.1	snake_toxin	57..133	CDD:264434	8/43 (19%)
		STYKc	226..517	CDD:214568	60/241 (25%)
		STKc_BMPR2_AMHR2	228..528	CDD:270956	60/239 (25%)
XIP1	NP_199777.1	PLN00113	47..933	CDD:331614	84/392 (21%)
		leucine-rich repeat	73..97	CDD:275380
		leucine-rich repeat	98..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..196	CDD:275380
		leucine-rich repeat	197..220	CDD:275380
		leucine-rich repeat	221..244	CDD:275380
		leucine-rich repeat	245..269	CDD:275380
		leucine-rich repeat	270..293	CDD:275380
		leucine-rich repeat	294..317	CDD:275380
		leucine-rich repeat	318..389	CDD:275380
		leucine-rich repeat	342..366	CDD:275380
		leucine-rich repeat	367..386	CDD:275380
		leucine-rich repeat	390..413	CDD:275380
		leucine-rich repeat	414..437	CDD:275380
		leucine-rich repeat	438..461	CDD:275380
		leucine-rich repeat	462..485	CDD:275380
		leucine-rich repeat	486..509	CDD:275380
		leucine-rich repeat	510..531	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000