DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wit and AT2G19210

DIOPT Version :9

Sequence 1:	NP_001261395.1	Gene:	wit / 44096	FlyBaseID:	FBgn0024179	Length:	913	Species:	Drosophila melanogaster
Sequence 2:	NP_179511.1	Gene:	AT2G19210 / 816438	AraportID:	AT2G19210	Length:	881	Species:	Arabidopsis thaliana

Alignment Length:	300	Identity:	75/300 - (25%)
Similarity:	122/300 - (40%)	Gaps:	75/300 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 LASTMLGLAGGLTALTIGIFLAVQYCRTAKEKPEPEESPLAPSGP--------GYSSNLRNVDNM 224
            |.::::|:.|  ..|.|.:||..      |::.....|....:||        .||..::..:|.
plant   522 LVASVVGVLG--LVLAIALFLLY------KKRHRRGGSGGVRAGPLDTTKRYYKYSEVVKVTNNF 578

  Fly   225 NLIGMLGSGKYGTVMKGLLHDQEVAVKIYPEEHHQYY------------VNERNIYALPLMECPA 277
            ..:  ||.|.:|.|..|:|:|.:|||||..|...|.|            |:.:|:.||
plant   579 ERV--LGQGGFGKVYHGVLNDDQVAVKILSESSAQGYKEFRAEVELLLRVHHKNLTAL------- 634

  Fly   278 LLSYFGYDERCTMDGRMEYQLVLSLAPLGCLQDWLIAN---TLTFSECCGMLRSITRGISHLHTE 339
                .||   |....:|  .|:......|.|.|:|...   .|::.|...:.....:|:.:||..
plant   635 ----IGY---CHEGKKM--ALIYEFMANGTLGDYLSGEKSYVLSWEERLQISLDAAQGLEYLHNG 690

  Fly   340 LRLGDQHKPCVAHRDINTRNVLVQADLSCCIADFGFALKVF--GSKYEYKGEVAMAETKSINEVG 402
            .      ||.:..||:...|:|:...|...|||||.:..|.  |:.         .:|.::  .|
plant   691 C------KPPIVQRDVKPANILINEKLQAKIADFGLSRSVALDGNN---------QDTTAV--AG 738

  Fly   403 TLRYMAPELLEGAVNLRDCETSLKQMDVYALGLVLWEVAT 442
            |:.|:.||       ....:...::.|:|:.|:||.||.:
plant   739 TIGYLDPE-------YHLTQKLSEKSDIYSFGVVLLEVVS 771

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wit	NP_001261395.1	snake_toxin	57..133	CDD:264434
		STYKc	226..517	CDD:214568	61/233 (26%)
		STKc_BMPR2_AMHR2	228..528	CDD:270956	61/231 (26%)
AT2G19210	NP_179511.1	Malectin_like	34..357	CDD:289580
		leucine-rich repeat	415..438	CDD:275380
		LRR_8	417..473	CDD:290566
		leucine-rich repeat	439..462	CDD:275380
		leucine-rich repeat	463..488	CDD:275380
		STKc_IRAK	582..848	CDD:270968	61/229 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910