Protein Alignment wit and bmpr1aa

DIOPT Version :10

• Sequence 1: NP_001261395.1
• Gene: wit / 44096
• FlyBaseID: FBgn0024179
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_571696.2
• Gene: bmpr1aa / 58145
• ZFINID: ZDB-GENE-000502-1
• Length: 527
• Species: Danio rerio
• Alignment Length: 500
• Identity: 132/500 - (26%)
• Similarity: 211/500 - (42%)
• Gaps: 80/500 - (16%)

  Fly    61 PSEPHRRTC-PDGYTFCFTIWNQTANGARVVKQGCWKDNTDRTSICSQSECTSS--APTSKTSSL 122
            |.:....|| .:|.  ||.|..:..||..::..||.|...      |..:|..|  |.|.:|..
Zfish    68 PDDAKNNTCETNGQ--CFAIIEEDENGDVILSSGCMKYEG------SHFQCKDSQFAQTRRTIE- 123

  Fly   123 YYCCCSGGVCNAQYSVVEPAPLELGSNEGRTSITNRATEKQHQSFLASTMLGLAGGLTALTIGIF 187
               ||....||..   ::|   ||...:      :...:....:||.|..:... .|..:|:..:
Zfish   124 ---CCQFDFCNQD---LKP---ELPPRD------SEPPDPHWLAFLISVTVCFC-ALICVTVICY 172

  Fly   188 LAVQYCRTAKEK------------PEPE-------ESPLAPSGPGYSSNLRN--VDNMNLIGMLG 231
            ...:: :|.:::            |..|       :|..:.||.|....::.  ...:..:.|:|
Zfish   173 YRYKW-QTERQRYHRDLEQDEAFIPAGESLKDLINQSQTSGSGSGLPLLVQRTIAKQIQTVRMIG 236

  Fly   232 SGKYGTVMKGLLHDQEVAVKIYPEEHHQYYVNERNIYALPLMECPALLSYFGYDERCTMDGRMEY 296
            .|:||.|..|....::||||::.......:..|..||...||....:|.:...|...|......|
Zfish   237 KGRYGEVWLGRWRGEKVAVKVFFTREEASWFRETEIYQTVLMRHENILGFIAADINGTGASTQLY 301

  Fly   297 QLVLSLAPLGCLQDWLIANT--------LTFSECCGMLRSITRGISHLHTELRLGDQHKPCVAHR 353
             |:......|.|.|:|...|        |.||..|        |:.|||||: .|.|.||.:|||
Zfish   302 -LITDYHENGSLYDYLKFTTLDTQALLRLAFSAAC--------GLCHLHTEI-YGTQGKPAIAHR 356

  Fly   354 DINTRNVLVQADLSCCIADFGFALKVFGSKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAVNL 418
            |:.::|:|::.:.:|||||.|.|:|       :..:....:......:||.||||||:|:..:|.
Zfish   357 DLKSKNILIKKNGTCCIADLGLAVK-------FNSDTNEVDLPLSTRMGTRRYMAPEVLDETLNK 414

  Fly   419 RDCETSLKQMDVYALGLVLWEVATRCSDFYAPGQATPPYKAPYEQEVGSHPSFDQMQALVVRHKA 483
            ...:..: ..|:|:.|||:||:|.||    ..|.....|:.||.:.|.|.||::.|..:|.....
Zfish   415 NHFQAYI-MADIYSYGLVIWEMARRC----VTGGIVEEYQLPYYEMVPSDPSYEDMLEVVCVKGL 474

  Fly   484 RPLFPTGWGGGAAAKVVRDTCEDCWDHDADARLTSLCAEERMQEM 528
            ||.....|......:.:.....:||.|:..:|||.|..::.:.:|
Zfish   475 RPTVSNRWNSDECLRAMLKLMSECWAHNPASRLTILRVKKTLAKM 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wit	NP_001261395.1	TFP_LU_ECD_Wit	25..138	CDD:467138	22/79 (28%)
		STKc_BMPR2_AMHR2	228..528	CDD:270956	94/307 (31%)
bmpr1aa	NP_571696.2	TFP_LU_ECD_BMPR1A	57..140	CDD:467132	25/89 (28%)
		TGF_beta_GS	200..227	CDD:462503	4/26 (15%)
		STKc_BMPR1a	233..519	CDD:271122	94/307 (31%)