Protein Alignment wit and acvr2aa

DIOPT Version :9

• Sequence 1: NP_001261395.1
• Gene: wit / 44096
• FlyBaseID: FBgn0024179
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: XP_021334336.1
• Gene: acvr2aa / 553359
• ZFINID: ZDB-GENE-980526-227
• Length: 538
• Species: Danio rerio
• Alignment Length: 524
• Identity: 166/524 - (31%)
• Similarity: 262/524 - (50%)
• Gaps: 90/524 - (17%)

  Fly    76 CFTIWNQTANGARVVKQGCWKDNTDRTSICSQS-ECTSSAPTSKTSSLYYCCCSGGVCNAQY--- 136
            ||..|...:....:||||||.|:.:    |..| ||...   .:...:::|||.|.:||.::
Zfish    61 CFATWRNVSGTVEIVKQGCWLDDVN----CYDSTECVEK---KEDPDVFFCCCEGNMCNEKFFYN 118

  Fly   137 ----SVVEPAPLELGSNEGRT--SITNRATEKQHQSFLASTMLGL---AGGLTALTIGIFLAVQY 192
                .|...||.....::.:.  :.:|..|:|..   |.||:|..   ..|:.|:.:..|...::
Zfish   119 PNTAPVQSKAPFSDTKSDTKVFKATSNPLTQKPP---LFSTLLYSIVPIMGIAAIVLLSFWMYRH 180

  Fly   193 CRTAK---------------EKPEP-EESPLAPSGPGYSSNLRNVDNMNLIGMLGSGKYGTVMKG 241
            .:.|.               |.|.| ..||.....|           :.|:.:...|::|.|.|.
Zfish   181 HKLAYPPVLVPTQHAFHIMIEDPGPMPPSPTLVQKP-----------LQLLEIKARGRFGCVWKA 234

  Fly   242 LLHDQEVAVKIYPEEHHQYYVNERNIYALPLMECPALLSYFGYDER-CTMDGRMEYQLVLSLAPL 305
            .|.:..|||||:|.:....:.||.:||.:|.|....:|.:.|.::| ..:|  :|..|:.:....
Zfish   235 QLLNDYVAVKIFPIQDKLSWQNEYDIYNIPGMRHENILQFIGAEKRGSNLD--IELWLITAYHEK 297

  Fly   306 GCLQDWLIANTLTFSECCGMLRSITRGISHLHTELRLG--DQHKPCVAHRDINTRNVLVQADLSC 368
            ..|.|:|.||.:|::|.|.:.:::.||:::||::.. |  |.|||.:||||..::|||::.:|:.
Zfish   298 SSLTDYLKANVVTWNELCHIAQTMARGLAYLHSDFP-GHRDGHKPAIAHRDFKSKNVLLKTNLTA 361

  Fly   369 CIADFGFALKVFGSKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAVNL-RDCETSLKQMDVYA 432
            ||||||.|||.         |...:...:..:|||.||||||:||||:|. ||   :..::|:||
Zfish   362 CIADFGLALKF---------EAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRD---AFLRIDMYA 414

  Fly   433 LGLVLWEVATRCSDFYAPGQATPPYKAPYEQEVGSHPSFDQMQALVVRHKARPLFPTGWGGGAAA 497
            :||||||:|.||:....|   ...|..|:|:|||.||:.:.||.:||..|.||.....|......
Zfish   415 VGLVLWELAARCTASDGP---VDEYMLPFEEEVGQHPTLEDMQEVVVHKKLRPTLRECWQKHPGL 476

  Fly   498 KVVRDTCEDCWDHDADARLTSLCAEERMQEMSTLRPRAQAQPSSPLLNTNNLVASPTAEQGINII 562
            .::.:|.|:||||:|:|||::.|.|||:.:|       |.|.|         |::|  |:.:.::
Zfish   477 AMLCETIEECWDHEAEARLSAGCVEERVVQM-------QRQTS---------VSAP--EEIVTVV 523

  Fly   563 ATTT 566
            ...|
Zfish   524 TMVT 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wit	NP_001261395.1	snake_toxin	57..133	CDD:264434	18/57 (32%)
		STYKc	226..517	CDD:214568	113/294 (38%)
		STKc_BMPR2_AMHR2	228..528	CDD:270956	117/303 (39%)
acvr2aa	XP_021334336.1	Activin_recp	43..115	CDD:307282	20/60 (33%)
		STKc_ACVR2a	221..510	CDD:271043	119/313 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG3653
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D191771at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820